Nationals vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for July 22

Odds updated as of 11:12 p.m.

Wednesday's slate in the MLB includes a matchup between the Washington Nationals and the Colorado Rockies.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information about this matchup.

Nationals vs Rockies Game Info

• Washington Nationals (51-50) vs. Colorado Rockies (40-62)
• Date: Wednesday, July 22, 2026
• Time: 3:10 p.m. ET
• Venue: Coors Field -- Denver, Colorado
• Coverage: Rockies.TV and Nationals.TV

Nationals vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: WSH: (-132) | COL: (+112)
• Spread: WSH: -1.5 (+116) | COL: +1.5 (-140)
• Total: 11.5 -- Over: (-105) | Under: (-115)

Nationals vs Rockies Probable Starting Pitchers

Probable Pitchers: Cade Cavalli (Nationals) - 6-4, 3.78 ERA vs Gabriel Hughes (Rockies) - 0-1, 3.14 ERA

The Nationals will look to Cade Cavalli (6-4) versus the Rockies and Gabriel Hughes (0-1). When Cavalli starts, his team is 11-10-0 against the spread this season. Cavalli's team has been victorious in 33.3% of the games he's started as the moneyline favorite with a record of 2-4. Hughes has started two games with set spreads, and the Rockies went 1-1-0. The Rockies were the moneyline underdog for one Hughes start this season -- they lost.

Nationals vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Nationals win (67.8%)

Nationals vs Rockies Moneyline

• Looking at the moneyline for Rockies-Nationals, Colorado is the underdog at +112, and Washington is -132 playing on the road.

Nationals vs Rockies Spread

• The Rockies are +1.5 on the spread (-140 to cover), and Washington is +116 to cover the runline.

Nationals vs Rockies Over/Under

• An over/under of 11.5 has been set for Nationals-Rockies on July 22, with the over being -105 and the under -115.

Bet on Washington Nationals vs. Colorado Rockies on FanDuel today!

Nationals vs Rockies Betting Trends

• The Nationals have been victorious in 10, or 52.6%, of the 19 contests they have been chosen as favorites in this season.
• This season Washington has been victorious six times in eight chances when named as a favorite of at least -132 on the moneyline.
• The Nationals and their opponents have gone over the total this season in 56 of their 99 opportunities.
• The Nationals have posted a record of 57-42-0 against the spread this season.
• The Rockies have won 40 of the 98 games they were listed as the moneyline underdog this season (40.8%).
• Colorado has a record of 37-53 when it has played as a moneyline underdog with odds of +112 or longer (41.1%).
• In the 100 games bookmakers have set an over/under for the Rockies, they have combined with opponents to go over the total 46 times (46-51-3).
• The Rockies have a 54-46-0 record against the spread this season (covering 54% of the time).

Nationals Player Leaders

• James Wood leads Washington in OBP (.401), slugging percentage (.553) and total hits (105) this season. He has a .271 batting average.
• Among all qualifying hitters in MLB, he is 49th in batting average, fourth in on-base percentage, and eighth in slugging.
• C.J. Abrams has 19 doubles, two triples, 22 home runs and 35 walks. He's batting .275 and slugging .521 with an on-base percentage of .350.
• Among all qualifying hitters, he is 42nd in batting average, 48th in on-base percentage and 15th in slugging percentage.
• Abrams has picked up at least one hit in two straight games. In his last five games he is batting .273 with two doubles, two home runs, a walk and five RBIs.
• Luis Garcia has collected 87 base hits, an OBP of .311 and a slugging percentage of .542 this season.
• Curtis Mead is batting .262 with a .354 OBP and 48 RBI for Washington this season.
• Mead has safely hit in two straight games. During his last five outings he is hitting .500 with four doubles, a home run, two walks and five RBIs.

Rockies Player Leaders

• T.J. Rumfield has an on-base percentage of .379 and a slugging percentage of .476. Both lead the Rockies. He's batting .296.
• Including all qualifying players in the big leagues, his batting average puts him 10th, his on-base percentage is 14th, and he is 34th in slugging.
• Jake McCarthy is batting .305 with 19 doubles, six triples, 10 home runs and 18 walks. He's slugging .512 with an on-base percentage of .350.
• Including all qualified players, he ranks sixth in batting average, 48th in on-base percentage and 18th in slugging percentage.
• Hunter Goodman has racked up 89 hits, a team-best for the Rockies.
• Kyle Karros is hitting .260 with 18 doubles, two triples, nine home runs and 41 walks.

Nationals vs Rockies Head to Head

• 7/20/2026: 7-3 WSH (Favorite: Nationals, Spread: -1.5, Total: 12, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/19/2025: 4-3 WSH (Favorite: Nationals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 6/17/2025: 10-6 COL (Favorite: Nationals, Spread: -1.5, Total: 9, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 6/16/2025: 6-4 COL (Favorite: Nationals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 4/20/2025: 3-1 COL (Favorite: Nationals, Spread: -1.5, Total: 10.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 4/20/2025: 3-2 WSH (Favorite: Rockies, Spread: -1.5, Total: 10.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/19/2025: 12-11 WSH (Favorite: Nationals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 8/22/2024: 8-3 WSH (Favorite: Nationals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 8/21/2024: 6-1 WSH (Favorite: Nationals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 8/20/2024: 3-1 COL (Favorite: Nationals, Spread: -1.5, Total: 8, Favorite Moneyline: -156, Underdog Moneyline: +132)

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