Mariners vs Cubs Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 22

Odds updated as of 4:12 a.m.

The Seattle Mariners will take on the Chicago Cubs in MLB action on Saturday.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Mariners vs Cubs Game Info

• Seattle Mariners (61-68) vs. Chicago Cubs (74-55)
• Date: Saturday, August 22, 2026
• Time: 7:15 p.m. ET
• Venue: T-Mobile Park -- Seattle, Washington
• Coverage: FOX

Mariners vs Cubs Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-108) | CHC: (+100)
• Spread: SEA: +1.5 (-192) | CHC: -1.5 (+158)
• Total: 7.5 -- Over: (-124) | Under: (+102)

Mariners vs Cubs Probable Starting Pitchers

Probable Pitchers: Kade Anderson (Mariners) - 0-0, 0.00 ERA vs David Peterson (Cubs) - 7-7, 5.29 ERA

This contest's pitching matchup is set, as the Mariners will send Kade Anderson to the mound, while David Peterson (7-7) will get the nod for the Cubs. Anderson did not appear in a game when his team was the moneyline favorite last season. The Cubs have gone 7-8-0 ATS in Peterson's 15 starts that had a set spread. The Cubs have a 2-4 record in Peterson's six starts this season when they were the underdog on the moneyline.

Mariners vs Cubs Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (57.9%)

Mariners vs Cubs Moneyline

• Chicago is a +100 underdog on the moneyline, while Seattle is a -108 favorite at home.

Mariners vs Cubs Spread

• The Cubs are 1.5-run favorites against the spread for this matchup with the Mariners. The Cubs are +158 to cover, while the Mariners are -192 to cover as a 1.5-run underdog on the runline.

Mariners vs Cubs Over/Under

• Mariners versus Cubs, on Aug. 22, has an over/under of 7.5, with the over being -124 and the under +102.

Bet on Seattle Mariners vs. Chicago Cubs on FanDuel today!

Mariners vs Cubs Betting Trends

• The Mariners have been favorites in 100 games this season and have come away with the win 50 times (50%) in those contests.
• This year Seattle has won 51 of 101 games when listed as at least -108 on the moneyline.
• The Mariners and their opponents have gone over the total this season in 64 of their 128 opportunities.
• The Mariners are 46-82-0 against the spread in their 128 games with a line set by sportsbooks this season.
• The Cubs have won 21 of the 38 games they were listed as the moneyline underdog this season (55.3%).
• Chicago has a 14-13 record (winning 51.9% of its games) when it has played as a moneyline underdog of +100 or longer.
• The Cubs have combined with opponents to hit the over on the total 67 times this season for a 67-57-0 record against the over/under.
• The Cubs have covered 49.2% of their games this season, going 61-63-0 ATS.

Mariners Player Leaders

• Randy Arozarena leads Seattle with 122 hits, batting .271 this season with 44 extra-base hits. He has an on-base percentage of .365 and a slugging percentage of .447.
• Among qualifying hitters in baseball, his batting average ranks 39th, his on-base percentage ranks 22nd, and he is 46th in slugging.
• Josh Naylor has an OPS of .701, fueled by an OBP of .331 and a team-best slugging percentage of .370 this season. He's batting .268.
• His batting average is 45th among qualified players, his on-base percentage 73rd, and his slugging percentage 119th.
• Cole Young has collected 120 base hits, an OBP of .315 and a slugging percentage of .395 this season.
• Julio Rodriguez has been key for Seattle with 117 hits, an OBP of .316 plus a slugging percentage of .414.
• Rodriguez takes a two-game hitting streak into this game. During his last five outings he is batting .130 with a double and an RBI.

Cubs Player Leaders

• Pete Crow-Armstrong has put up a team-best OBP (.378) and slugging percentage (.554), and leads the Cubs in hits (137, while batting .279).
• Including all the qualifying hitters in the majors, his batting average puts him 27th, his on-base percentage is 11th, and he is second in slugging.
• Alex Bregman is batting .258 with 24 doubles, a triple, 18 home runs and 63 walks. He's slugging .418 with an on-base percentage of .347.
• His batting average ranks 68th among all qualified players, his on-base percentage is 50th, and he is 77th in slugging.
• Nico Hoerner is hitting .263 with 26 doubles, a triple, seven home runs and 40 walks.
• Seiya Suzuki is batting .267 with 24 doubles, 22 home runs and 58 walks.

Mariners vs Cubs Head to Head

• 8/21/2026: 6-5 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: +100)
• 6/22/2025: 14-6 SEA (Favorite: Mariners, Spread: -1.5, Total: 11.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 6/21/2025: 10-7 CHC (Favorite: Cubs, Spread: -1.5, Total: 12.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 6/20/2025: 9-4 SEA (Favorite: Cubs, Spread: -1.5, Total: 9.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 4/14/2024: 3-2 CHC (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/13/2024: 4-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 4/12/2024: 4-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/12/2023: 5-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 11, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/11/2023: 14-9 CHC (Favorite: Cubs, Spread: -1.5, Total: 10.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 4/10/2023: 3-2 CHC (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)

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