Dodgers vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 12

Odds updated as of 7:12 a.m.

The Los Angeles Dodgers versus the San Francisco Giants is on the MLB schedule for Friday.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Dodgers vs Giants Game Info

• Los Angeles Dodgers (82-64) vs. San Francisco Giants (74-72)
• Date: Friday, September 12, 2025
• Time: 10:15 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: MLB Network, NBCS-BA, and SportsNet LA

Dodgers vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAD: (-154) | SF: (+130)
• Spread: LAD: -1.5 (+116) | SF: +1.5 (-140)
• Total: 7.5 -- Over: (-114) | Under: (-106)

Dodgers vs Giants Probable Starting Pitchers

Probable Pitchers: Yoshinobu Yamamoto (Dodgers) - 11-8, 2.72 ERA vs Justin Verlander (Giants) - 3-10, 4.09 ERA

The Dodgers will call on Yoshinobu Yamamoto (11-8) against the Giants and Justin Verlander (3-10). Yamamoto and his team have a record of 12-15-0 against the spread when he starts. Yamamoto's team has won 53.8% of his starts when they are favored on the moneyline (14-12). The Giants are 7-18-0 against the spread when Verlander starts. The Giants are 3-8 in Verlander's 11 starts this season that they were the underdog on the moneyline.

Dodgers vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Dodgers win (55.4%)

Dodgers vs Giants Moneyline

• The Dodgers vs Giants moneyline has Los Angeles as a -154 favorite, while San Francisco is a +130 underdog at home.

Dodgers vs Giants Spread

• The Dodgers are at the Giants and are favored by 1.5 runs (+116 to cover) on the runline. San Francisco is -140 to cover.

Dodgers vs Giants Over/Under

• An over/under of 7.5 has been set for Dodgers-Giants on Sept. 12, with the over being -114 and the under -106.

Bet on Los Angeles Dodgers vs. San Francisco Giants on FanDuel today!

Dodgers vs Giants Betting Trends

• The Dodgers have been chosen as favorites in 128 games this year and have walked away with the win 73 times (57%) in those games.
• This year Los Angeles has won 54 of 93 games when listed as at least -154 on the moneyline.
• The Dodgers and their opponents have hit the over in 68 of their 144 games with a total set by oddsmakers this season.
• The Dodgers have an against the spread record of 60-84-0 in 144 games with a line this season.
• The Giants have been the underdog on the moneyline 56 total times this season. They've finished 26-30 in those games.
• San Francisco has a 6-11 record (winning just 35.3% of its games) when it has played as a moneyline underdog of +130 or longer.
• The Giants have combined with opponents to hit the over on the total 69 times this season for a 69-69-7 record against the over/under.
• The Giants have a 68-77-0 record against the spread this season.

Dodgers Player Leaders

• Shohei Ohtani leads Los Angeles in OBP (.391), slugging percentage (.609) and total hits (154) this season. He has a .280 batting average.
• He is 24th in batting average, fourth in on-base percentage, and second in slugging among all qualified hitters in the majors.
• Ohtani hopes to build on a five-game hitting streak in this matchup. During his last five outings he is batting .375 with a double, two home runs, six walks and five RBIs.
• Mookie Betts is hitting .260 with 21 doubles, two triples, 18 home runs and 54 walks. He's slugging .409 with an on-base percentage of .328.
• Among qualifying hitters, he is 74th in batting average, 77th in on-base percentage and 89th in slugging percentage.
• Betts has picked up at least one hit in seven straight games. During his last 10 outings he is batting .395 with three doubles, a triple, four home runs, a walk and 15 RBIs.
• Freddie Freeman has collected 145 base hits, an OBP of .364 and a slugging percentage of .495 this season.
• Andy Pages has 24 home runs, 80 RBI and a batting average of .273 this season.
• Pages has safely hit in two straight games. In his last five games he is hitting .294 with a double and an RBI.

Giants Player Leaders

• Rafael Devers has racked up an on-base percentage of .378 and has 142 hits, both team-high numbers for the Giants. He's batting .260 and slugging .486.
• Including all qualified players in the majors, he ranks 74th in batting average, ninth in on-base percentage and 27th in slugging percentage.
• Jung Hoo Lee has 30 doubles, 11 triples, eight home runs and 44 walks while hitting .269. He's slugging .416 with an on-base percentage of .330.
• He is currently 42nd in batting average, 69th in on-base percentage and 84th in slugging percentage among all qualifying batters.
• Willy Adames has 19 doubles, two triples, 28 home runs and 69 walks while batting .229.
• Matt Chapman is batting .243 with 19 doubles, two triples, 21 home runs and 63 walks.

Dodgers vs Giants Head to Head

• 7/13/2025: 5-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/12/2025: 2-1 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 7/11/2025: 8-7 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 6/15/2025: 5-4 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 6/14/2025: 11-5 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 6/13/2025: 6-2 SF (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 7/25/2024: 6-4 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/24/2024: 8-3 SF (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 7/23/2024: 5-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 7/22/2024: 3-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!