Angels vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 21

Odds updated as of 2:12 a.m.

The MLB's Sunday schedule includes the Los Angeles Angels taking on the Colorado Rockies.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Angels vs Rockies Game Info

• Los Angeles Angels (70-85) vs. Colorado Rockies (42-113)
• Date: Sunday, September 21, 2025
• Time: 3:10 p.m. ET
• Venue: Coors Field -- Denver, Colorado
• Coverage: COLR and FDSW

Angels vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAA: (-112) | COL: (-104)
• Spread: LAA: -1.5 (+130) | COL: +1.5 (-156)
• Total: 11.5 -- Over: (-122) | Under: (-100)

Angels vs Rockies Probable Starting Pitchers

Probable Pitchers: Caden Dana (Angels) - 0-2, 7.45 ERA vs Kyle Freeland (Rockies) - 4-16, 5.14 ERA

The probable pitchers are Caden Dana (0-2) for the Angels and Kyle Freeland (4-16) for the Rockies. Dana and his team have a record of 1-2-0 against the spread when he starts. Dana's team lost his only start as a favorite this season. The Rockies have a 12-16-0 record against the spread in Freeland's starts. The Rockies are 7-20 in Freeland's 27 starts this season that they were the underdog on the moneyline.

Angels vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Rockies win (54.7%)

Angels vs Rockies Moneyline

• Los Angeles is a -112 favorite on the moneyline, while Colorado is a -104 underdog at home.

Angels vs Rockies Spread

• The Rockies are +1.5 on the run line against the Angels. The Rockies are -156 to cover, and the Angels are +130.

Angels vs Rockies Over/Under

• Angels versus Rockies, on Sept. 21, has an over/under of 11.5, with the over being -122 and the under -100.

Bet on Los Angeles Angels vs. Colorado Rockies on FanDuel today!

Angels vs Rockies Betting Trends

• The Angels have won in 18, or 50%, of the 36 contests they have been named as odds-on favorites in this year.
• This season Los Angeles has come away with a win 18 times in 35 chances when named as a favorite of at least -112 on the moneyline.
• The Angels' games have gone over the total in 82 of their 153 opportunities.
• The Angels have an against the spread record of 81-72-0 in 153 games with a line this season.
• The Rockies are 38-108 in games they were the underdog on the moneyline (winning 26% of those games).
• Colorado has a 38-108 record (winning just 26% of its games) when playing as a moneyline underdog of -104 or longer.
• The Rockies have had an over/under set by oddsmakers 150 times, and have combined with opponents to go over the total in 66 of those games (66-79-5).
• The Rockies have a 60-90-0 record against the spread this season.

Angels Player Leaders

• Taylor Ward is batting .228 with 31 doubles, two triples, 34 home runs and 72 walks. He has an on-base percentage of .316 while slugging .472.
• Among all qualified hitters in MLB, he is 137th in batting average, 101st in on-base percentage, and 38th in slugging.
• Ward has hit safely in four straight games. During his last five outings he is batting .368 with three home runs and three RBIs.
• Jo Adell leads Los Angeles in total hits (118) this season while batting .236 with 54 extra-base hits. He's slugging .491 with an on-base percentage of .295.
• Among qualifying hitters, he ranks 121st in batting average, 125th in on-base percentage and 20th in slugging percentage.
• Nolan Schanuel has collected 126 base hits, an OBP of .355 and a slugging percentage of .391 this season.
• Schanuel enters this matchup with two games in a row with at least one hit. During his last five outings he is batting .167 with a double, a home run and three RBIs.
• Mike Trout leads Los Angeles with an OBP of .358 this season while batting .229 with 85 walks and 67 runs scored.

Rockies Player Leaders

• Hunter Goodman has accumulated an on-base percentage of .327, a slugging percentage of .527, and has 144 hits, all club-bests for the Rockies (while batting .281).
• Including all qualifying hitters, he ranks 23rd in batting average, while his on-base percentage is 77th and he is 11th in slugging.
• Goodman hopes to build on a five-game hitting streak in this matchup. During his last five outings he is batting .381 with a double, a triple, two walks and an RBI.
• Mickey Moniak is hitting .272 with 18 doubles, eight triples, 24 home runs and 21 walks. He's slugging .525 with an on-base percentage of .308.
• Jordan Beck has put up an on-base percentage of .327, a team-high for the Rockies.
• Tyler Freeman is hitting .281 with 20 doubles, two triples, two home runs and 34 walks.

Angels vs Rockies Head to Head

• 9/20/2025: 3-0 LAA (Favorite: Angels, Spread: -1.5, Total: 11.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/19/2025: 7-6 COL (Favorite: Angels, Spread: -1.5, Total: 11.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/1/2024: 5-4 COL (Favorite: Angels, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/31/2024: 2-1 COL (Favorite: Angels, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 7/30/2024: 10-7 LAA (Favorite: Angels, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 6/25/2023: 4-3 COL (Favorite: Angels, Spread: -1.5, Total: 12.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 6/24/2023: 25-1 LAA (Favorite: Angels, Spread: -1.5, Total: 12.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 6/23/2023: 7-4 COL (Favorite: Angels, Spread: -1.5, Total: 12, Favorite Moneyline: -156, Underdog Moneyline: +132)

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