White Sox vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 5

Odds updated as of 2:12 a.m.

The Chicago White Sox versus the Minnesota Twins is on the MLB schedule for Saturday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information about this game.

White Sox vs Twins Game Info

• Chicago White Sox (74-67) vs. Minnesota Twins (67-74)
• Date: Saturday, September 5, 2026
• Time: 7:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and Twins.TV

White Sox vs Twins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHW: (-124) | MIN: (+106)
• Spread: CHW: -1.5 (+158) | MIN: +1.5 (-192)
• Total: 8.5 -- Over: (-102) | Under: (-120)

White Sox vs Twins Probable Starting Pitchers

Probable Pitchers: Anthony Kay (White Sox) - 9-7, 4.35 ERA vs Taj Bradley (Twins) - 10-6, 3.85 ERA

The White Sox will give the nod to Anthony Kay (9-7) against the Twins and Taj Bradley (10-6). Kay's team is 18-7-0 against the spread in his starts this season. When Kay starts a game and his team is the favorite on the moneyline, they have a record of 1-2. The Twins have a 17-9-0 ATS record in Bradley's 26 starts with a set spread. The Twins have been the moneyline underdog in 15 of Bradley's starts this season, and they went 9-6 in those matchups.

White Sox vs Twins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (54.6%)

White Sox vs Twins Moneyline

• The moneyline numbers for White Sox vs. Twins reveal Chicago as the favorite (-124) and Minnesota as the underdog (+106) on the road.

White Sox vs Twins Spread

• The White Sox are hosting the Twins and are favored by 1.5 runs (+158 to cover) on the runline. Minnesota is -192 to cover.

White Sox vs Twins Over/Under

• An over/under of 8.5 has been set for White Sox-Twins on Sept. 5, with the over being -102 and the under -120.

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White Sox vs Twins Betting Trends

• The White Sox have won in 18, or 60%, of the 30 contests they have been named as odds-on favorites in this year.
• This season Chicago has come away with a win 10 times in 16 chances when named as a favorite of at least -124 on the moneyline.
• Contests with the White Sox have gone over the total set by oddsmakers in 75 of 138 chances this season.
• The White Sox are 80-58-0 against the spread in their 138 games that had a posted line this season.
• The Twins have compiled a 36-46 record in games they were the underdog on the moneyline (winning 43.9% of those games).
• Minnesota has a 30-35 record (winning 46.2% of its games) when it has played as a moneyline underdog of +106 or longer.
• The Twins have had an over/under set by bookmakers 138 times, and have combined with opponents to go over the total in 77 of those games (77-58-3).
• The Twins have collected a 74-64-0 record against the spread this season (covering 53.6% of the time).

White Sox Player Leaders

• Miguel Vargas leads Chicago with 128 hits, batting .251 this season with 60 extra-base hits. He has an on-base percentage of .363 and a slugging percentage of .484.
• Among all qualified hitters in the majors, his batting average ranks 78th, his on-base percentage ranks 24th, and he is 24th in slugging.
• Vargas has recorded a base hit in two games in a row. During his last five outings he is batting .300 with two walks.
• Chase Meidroth leads Chicago in slugging percentage (.400) thanks to 39 extra-base hits. He's batting .273 with an on-base percentage of .346.
• Among all qualified hitters, he ranks 36th in batting average, 44th in on-base percentage and 93rd in slugging percentage.
• Sam Antonacci leads Chicago with an OBP of .364 this season while batting .265 with 40 walks and 70 runs scored.
• Antonacci enters this game with two games in a row with at least one hit. In his last five games he is batting .222 with a double, three walks and an RBI.
• Tristan Peters has been key for Chicago with 105 hits, an OBP of .344 plus a slugging percentage of .466.

Twins Player Leaders

• Brooks Lee has 21 doubles, three triples, 22 home runs and 33 walks while batting .250. He's slugging .435 with an on-base percentage of .299.
• Including all the qualifying hitters in the majors, he ranks 82nd in batting average, 121st in on-base percentage and 58th in slugging percentage.
• Josh Bell paces his team with a .417 slugging percentage. He has a batting average of .255 with an on-base percentage of .319.
• His batting average is 66th among all qualified players, his on-base percentage is 90th, and he is 75th in slugging.
• Kody Clemens has racked up 107 hits, a team-best for the Twins.
• Luke Keaschall's .369 on-base percentage leads his team.

White Sox vs Twins Head to Head

• 9/4/2026: 4-1 CHW (Favorite: White Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/30/2026: 5-1 MIN (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -114, Underdog Moneyline: +104)
• 8/29/2026: 3-2 CHW (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -110, Underdog Moneyline: +100)
• 8/28/2026: 7-4 CHW (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +116)
• 6/3/2026: 8-0 CHW (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 6/2/2026: 6-4 MIN (Favorite: White Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/1/2026: 9-6 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 5/28/2026: 6-2 CHW (Favorite: White Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 5/27/2026: 15-2 CHW (Favorite: White Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 5/26/2026: 5-3 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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