Red Sox vs Orioles Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 5

Odds updated as of 2:12 a.m.

The MLB slate on Saturday includes the Boston Red Sox facing the Baltimore Orioles.

We've got you covered, in terms of the most important info about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Red Sox vs Orioles Game Info

• Boston Red Sox (77-65) vs. Baltimore Orioles (69-73)
• Date: Saturday, September 5, 2026
• Time: 7:05 p.m. ET
• Venue: Oriole Park at Camden Yards -- Baltimore, Maryland
• Coverage: MASN and NESN

Red Sox vs Orioles Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BOS: (-138) | BAL: (+118)
• Spread: BOS: -1.5 (+118) | BAL: +1.5 (-142)
• Total: 8.5 -- Over: (+104) | Under: (-128)

Red Sox vs Orioles Probable Starting Pitchers

Probable Pitchers: Sonny Gray (Red Sox) - 16-4, 2.82 ERA vs Chris Bassitt (Orioles) - 6-4, 4.97 ERA

This contest's pitching matchup is set, as the Red Sox will send Sonny Gray (16-4) to the mound, while Chris Bassitt (6-4) will get the nod for the Orioles. When Gray starts, his team is 16-8-0 against the spread this season. Gray's team has been victorious in 66.7% of the games he's started as the moneyline favorite with a record of 14-7. The Orioles have gone 8-6-0 against the spread when Bassitt starts. The Orioles have been the underdog on the moneyline in eight of Bassitt's starts this season, and they went 6-2 in those games.

Red Sox vs Orioles Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Red Sox win (54.6%)

Red Sox vs Orioles Moneyline

• Looking at the moneyline for Orioles-Red Sox, Baltimore is the underdog at +118, and Boston is -138 playing on the road.

Red Sox vs Orioles Spread

• The Orioles are at +1.5 on the runline against the Red Sox. The Orioles are -142 to cover the spread, and the Red Sox are +118.

Red Sox vs Orioles Over/Under

• An over/under of 8.5 has been set for Red Sox-Orioles on Sept. 5, with the over being +104 and the under -128.

Bet on Boston Red Sox vs. Baltimore Orioles on FanDuel today!

Red Sox vs Orioles Betting Trends

• The Red Sox have been victorious in 53, or 54.1%, of the 98 contests they have been chosen as favorites in this season.
• This season Boston has come away with a win 26 times in 46 chances when named as a favorite of at least -138 on the moneyline.
• Contests with the Red Sox have gone over the total set by sportsbooks in 66 of 140 chances this season.
• The Red Sox are 66-74-0 against the spread in their 140 games that had a posted line this season.
• The Orioles have been the underdog on the moneyline 69 total times this season. They've finished 32-37 in those games.
• When it has played as a moneyline underdog with odds of +118 or longer, Baltimore has a 10-16 record (winning only 38.5% of its games).
• The Orioles have played in 141 games with a set over/under, and have combined with opponents to go over the total 71 times (71-66-4).
• The Orioles have a 73-68-0 record ATS this season (covering 51.8% of the time).

Red Sox Player Leaders

• Wilyer Abreu is hitting .258 with 34 doubles, four triples, 23 home runs and 62 walks. He has an on-base percentage of .335 while slugging .468.
• He is 64th in batting average, 63rd in on-base percentage, and 33rd in slugging among all qualified hitters in baseball.
• Ceddanne Rafaela leads Boston in slugging percentage (.443) thanks to 51 extra-base hits. He's batting .282 with an on-base percentage of .317.
• He is 21st in batting average, 93rd in on-base percentage and 49th in slugging among qualifying batters.
• Caleb Durbin has 112 hits this season and has a slash line of .250/.327/.384.
• Jarren Duran has been key for Boston with 102 hits, an OBP of .260 plus a slugging percentage of .362.

Orioles Player Leaders

• Pete Alonso has accumulated a team-best OBP (.360) and slugging percentage (.502), and paces the Orioles in hits (142, while batting .269).
• Including all qualifying players in the big leagues, he is 45th in batting average, 26th in on-base percentage and 15th in slugging percentage.
• Gunnar Henderson is batting .220 with 24 doubles, five triples, 22 home runs and 58 walks. He's slugging .400 with an on-base percentage of .303.
• His batting average ranks 125th among all qualified players, his on-base percentage is 116th, and he is 93rd in slugging.
• Leody Taveras is batting .219 with 15 doubles, six triples, eight home runs and 40 walks.
• Coby Mayo is batting .221 with 13 doubles, three triples, 19 home runs and 26 walks.

Red Sox vs Orioles Head to Head

• 9/4/2026: 1-0 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/3/2026: 6-5 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 7/22/2026: 5-1 BAL (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/22/2026: 6-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 7/20/2026: 6-5 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 6/4/2026: 8-2 BAL (Favorite: Red Sox, Spread: -1.5, Total: 10.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/3/2026: 8-1 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 6/2/2026: 4-2 BAL (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 4/26/2026: 5-3 BOS (Favorite: Orioles, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/25/2026: 17-1 BOS (Favorite: Orioles, Spread: -1.5, Total: 7, Favorite Moneyline: -126, Underdog Moneyline: +108)

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