Cardinals vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 5

Odds updated as of 2:12 a.m.

The MLB's Saturday slate includes the St. Louis Cardinals taking on the Colorado Rockies.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Cardinals vs Rockies Game Info

• St. Louis Cardinals (71-71) vs. Colorado Rockies (54-87)
• Date: Saturday, September 5, 2026
• Time: 8:10 p.m. ET
• Venue: Coors Field -- Denver, Colorado
• Coverage: Rockies.TV and Cardinals.TV

Cardinals vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: STL: (-120) | COL: (+102)
• Spread: STL: -1.5 (+126) | COL: +1.5 (-152)
• Total: 10.5 -- Over: (-128) | Under: (+104)

Cardinals vs Rockies Probable Starting Pitchers

Probable Pitchers: Matthew Liberatore (Cardinals) - 5-13, 5.41 ERA vs Mason Adams (Rockies) - 0-0, 3.00 ERA

The Cardinals will call on Matthew Liberatore (5-13) against the Rockies and Mason Adams. Liberatore and his team are 13-13-0 ATS this season when he starts. Liberatore's team has a record of 5-3 this season when he starts and they are the favorite on the moneyline. Adams has started two games with set spreads, and the Rockies covered in both opportunities. The Rockies were the moneyline underdog for two Adams starts this season -- they split the games.

Cardinals vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (60.4%)

Cardinals vs Rockies Moneyline

• St. Louis is a -120 favorite on the moneyline, while Colorado is a +102 underdog at home.

Cardinals vs Rockies Spread

• The Rockies are at +1.5 on the runline against the Cardinals. The Rockies are -152 to cover the spread, and the Cardinals are +126.

Cardinals vs Rockies Over/Under

• A combined run total of 10.5 has been set for Cardinals-Rockies on Sept. 5, with the over at -128 and the under at +104.

Bet on St. Louis Cardinals vs. Colorado Rockies on FanDuel today!

Cardinals vs Rockies Betting Trends

• The Cardinals have been chosen as favorites in 43 games this year and have walked away with the win 24 times (55.8%) in those games.
• This season St. Louis has come away with a win 14 times in 24 chances when named as a favorite of at least -120 on the moneyline.
• The Cardinals and their opponents have hit the over in 61 of their 138 games with a total set by oddsmakers this season.
• The Cardinals have an against the spread mark of 75-63-0 in 138 games with a line this season.
• The Rockies have won 38.1% of the games this season they were the underdog on the moneyline (51-83).
• Colorado is 47-81 (winning only 36.7% of its games) when it has played as a moneyline underdog of +102 or longer.
• The Rockies have played in 138 games with an over/under set, and have combined with opponents to go over the total 65 times (65-70-3).
• The Rockies have put together a 75-63-0 record against the spread this season (covering 54.3% of the time).

Cardinals Player Leaders

• Alec Burleson is batting .282 with 33 doubles, a triple, 21 home runs and 48 walks. He has an on-base percentage of .346 while slugging .466.
• Among qualified hitters in baseball, he is 21st in batting average, 44th in on-base percentage, and 37th in slugging.
• Jordan Walker leads St. Louis with 155 hits and a team-best slugging percentage of .506. He's batting .289 with an on-base percentage of .345.
• Among qualifying hitters, his batting average ranks him 13th, his on-base percentage 47th, and his slugging percentage 13th.
• Walker has picked up at least one hit in four games in a row. During his last five outings he is hitting .273 with three doubles, a home run and two RBIs.
• Ivan Herrera leads St. Louis in OBP (.359) this season, fueled by 129 hits.
• Herrera has recorded a hit in two straight games. During his last five outings he is hitting .286 with a double, three walks and three RBIs.
• Nathan Church has 10 home runs, 47 RBI and a batting average of .242 this season.
• Church brings a four-game hitting streak into this game. During his last five outings he is hitting .250 with an RBI.

Rockies Player Leaders

• Jake McCarthy is batting .292 with 29 doubles, eight triples, 14 home runs and 25 walks. He's slugging .481 with an on-base percentage of .333.
• Including all the qualified hitters in MLB, he is 11th in batting average, 66th in on-base percentage and 27th in slugging percentage.
• TJ Rumfield has a .384 on-base percentage while slugging .442. Both lead his team. He has a batting average of .291.
• He is 12th in batting average, fifth in on-base percentage and 50th in slugging percentage in the big leagues.
• Hunter Goodman leads the Rockies with 113 hits.
• Willi Castro is hitting .260 with 20 doubles, a triple, 15 home runs and 41 walks.

Cardinals vs Rockies Head to Head

• 9/4/2026: 7-6 STL (Favorite: Cardinals, Spread: -1.5, Total: 11.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/9/2026: 7-4 STL (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -158, Underdog Moneyline: +146)
• 8/8/2026: 8-6 COL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +142)
• 8/7/2026: 3-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -164, Underdog Moneyline: +150)
• 8/13/2025: 6-5 COL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 8/11/2025: 3-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 7/23/2025: 6-0 COL (Favorite: Cardinals, Spread: -1.5, Total: 11, Favorite Moneyline: -186, Underdog Moneyline: +156)
• 7/22/2025: 8-4 COL (Favorite: Cardinals, Spread: -1.5, Total: 12, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 7/21/2025: 6-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 11.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 9/26/2024: 10-8 COL (Favorite: Cardinals, Spread: -1.5, Total: 10.5, Favorite Moneyline: -112, Underdog Moneyline: -104)

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