Twins vs Brewers Prediction, Odds, Moneyline, Spread & Over/Under for June 21

Odds updated as of 2:12 a.m.

The Minnesota Twins versus the Milwaukee Brewers is on the MLB schedule for Saturday.

All the info you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Twins vs Brewers Game Info

• Minnesota Twins (37-38) vs. Milwaukee Brewers (41-35)
• Date: Saturday, June 21, 2025
• Time: 2:10 p.m. ET
• Venue: Target Field -- Minneapolis, Minnesota
• Coverage: MNNT and FDSWI

Twins vs Brewers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIN: (-158) | MIL: (+134)
• Spread: MIN: -1.5 (+132) | MIL: +1.5 (-160)
• Total: 7.5 -- Over: (-115) | Under: (-105)

Twins vs Brewers Probable Starting Pitchers

Probable Pitchers: Simeon Woods Richardson (Twins) - 2-3, 5.13 ERA vs José Quintana (Brewers) - 4-2, 3.35 ERA

This contest's pitching matchup is set, as the Twins will send Simeon Woods Richardson (2-3) to the mound, while Jose Quintana (4-2) will get the nod for the Brewers. Woods Richardson and his team are 5-4-0 ATS this season when he starts. Woods Richardson's team is 4-2 this season when he starts and they are the moneyline favorite. The Brewers have a 5-4-0 record against the spread in Quintana's starts. The Brewers are 4-1 in Quintana's five starts this season that they were the moneyline underdog.

Twins vs Brewers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (58%)

Twins vs Brewers Moneyline

• Minnesota is the favorite, -158 on the moneyline, while Milwaukee is a +134 underdog on the road.

Twins vs Brewers Spread

• The Brewers are +1.5 on the spread (-160 to cover), and Minnesota is +132 to cover the runline.

Twins vs Brewers Over/Under

• Twins versus Brewers on June 21 has an over/under of 7.5 runs, with the odds on the over -115 and the under set at -105.

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Twins vs Brewers Betting Trends

• The Twins have been favorites in 47 games this season and have come away with the win 25 times (53.2%) in those contests.
• This season Minnesota has come away with a win 14 times in 19 chances when named as a favorite of at least -158 on the moneyline.
• The Twins and their opponents have gone over the total this season in 31 of their 72 opportunities.
• The Twins are 39-33-0 against the spread in their 72 games with a line set by sportsbooks this season.
• The Brewers have compiled a 15-23 record in games they were listed as the moneyline underdog (winning 39.5% of those games).
• Milwaukee has a 3-6 record (winning just 33.3% of its games) when it has played as a moneyline underdog of +134 or longer.
• In the 75 games bookmakers have set an over/under for the Brewers, they have combined with opponents to go over the total 30 times (30-44-1).
• The Brewers have put together a 38-37-0 record against the spread this season (covering 50.7% of the time).

Twins Player Leaders

• Byron Buxton leads Minnesota with 61 hits, batting .277 this season with 27 extra-base hits. He has an on-base percentage of .343 and a slugging percentage of .550.
• Among qualified hitters in the majors, his batting average ranks 42nd, his on-base percentage ranks 58th, and he is eighth in slugging.
• Trevor Larnach is hitting .256 with 11 doubles, a triple, 10 home runs and 24 walks, while slugging .420 with an on-base percentage of .323.
• He ranks 80th in batting average, 90th in on-base percentage and 87th in slugging in MLB.
• Ty France has hit five homers with a team-high .372 SLG this season.
• France heads into this game with two games in a row with at least one hit. During his last five outings he is batting .176 with two doubles and three RBIs.
• Willi Castro is batting .286 with a .369 OBP and 17 RBI for Minnesota this season.
• Castro heads into this matchup on a three-game hitting streak. During his last five outings he is batting .353 with a double and three walks.

Brewers Player Leaders

• Jackson Chourio has accumulated a slugging percentage of .463 and has 85 hits, both team-best figures for the Brewers. He's batting .264 and with an on-base percentage of .294.
• Including all the qualified hitters in the majors, he is 63rd in batting average, 133rd in on-base percentage and 44th in slugging percentage.
• Chourio takes a 10-game hitting streak into this game. During his last 10 games he is hitting .333 with four doubles, two triples, two home runs, three walks and eight RBIs.
• Christian Yelich is batting .252 with nine doubles, 14 home runs and 29 walks. He's slugging .441 with an on-base percentage of .330.
• Including all qualifying hitters, his batting average places him 89th, his on-base percentage ranks 76th, and he is 68th in slugging.
• Sal Frelick is batting .293 with eight doubles, three triples, four home runs and 21 walks.
• Brice Turang is batting .268 with 10 doubles, four home runs and 35 walks.

Twins vs Brewers Head to Head

• 6/20/2025: 17-6 MIL (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 5/18/2025: 5-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 5/17/2025: 7-0 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/16/2025: 3-0 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/20/2024: 8-4 MIL (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 4/3/2024: 7-3 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 4/2/2024: 3-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/23/2023: 8-7 MIL (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 8/22/2023: 7-3 MIL (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/13/2023: 7-5 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)

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