Tulane vs Duke Prediction, Odds, Picks, Best Bets for Week 3 2025

The Saturday slate in college football includes a matchup between the Tulane Green Wave and the Duke Blue Devils.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

Tulane vs Duke Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Tulane: (-122) | Duke: (+102)
• Spread: Tulane: -1.5 (-110) | Duke: +1.5 (-110)
• Total: 52.5 -- Over: (-110) | Under: (-110)

Tulane vs Duke Betting Trends

• Tulane has one win against the spread this year.
• Tulane owns one win ATS (1-1) as a 1.5-point favorite or greater this season.
• Tulane has had one game (of two) hit the over this season.
• Duke is winless against the spread this year.
• Duke doesn't have a win ATS (0-1) as a 1.5-point underdog or greater this season.
• All two Duke games have gone over the point total this season.

Tulane vs Duke Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Green Wave win (78.8%)

Tulane vs Duke Point Spread

Tulane is favored by 1.5 points over Duke. Tulane is -110 to cover the spread, with Duke being -110.

Tulane vs Duke Over/Under

Tulane versus Duke, on Sept. 13, has an over/under of 52.5, with the over being -110 and the under -110.

Tulane vs Duke Moneyline

Duke is a +102 underdog on the moneyline, while Tulane is a -122 favorite.

Tulane vs. Duke Points Insights

Tulane vs. Duke Game Info

• Game day: Saturday, September 13, 2025
• Game time: 8 p.m. ET
• TV channel: ESPN2
• Location: New Orleans, Louisiana
• Stadium: Yulman Stadium

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Check out even more in-depth Tulane vs. Duke analysis on FanDuel Research.