Reds vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for July 22

Odds updated as of 9:11 a.m.

The MLB slate on Tuesday includes the Cincinnati Reds facing the Washington Nationals.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Reds vs Nationals Game Info

• Cincinnati Reds (52-49) vs. Washington Nationals (40-60)
• Date: Tuesday, July 22, 2025
• Time: 6:45 p.m. ET
• Venue: Nationals Park -- Washington, District of Columbia
• Coverage: MASN and FDSOH

Reds vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CIN: (-136) | WSH: (+116)
• Spread: CIN: -1.5 (+118) | WSH: +1.5 (-142)
• Total: 9 -- Over: (-102) | Under: (-120)

Reds vs Nationals Probable Starting Pitchers

Probable Pitchers: Chase Burns (Reds) - 0-1, 6.19 ERA vs Brad Lord (Nationals) - 2-5, 3.46 ERA

The Reds will give the nod to Chase Burns (0-1) versus the Nationals and Brad Lord (2-5). When Burns starts, his team is 1-3-0 against the spread this season. Burns' team lost his only start as a favorite this season. The Nationals have a 2-3-0 record against the spread in Lord's starts. The Nationals have a 2-1 record in Lord's three starts this season when they were the moneyline underdog.

Reds vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (50.3%)

Reds vs Nationals Moneyline

• Cincinnati is the favorite, -136 on the moneyline, while Washington is a +116 underdog despite being at home.

Reds vs Nationals Spread

• The Nationals are +1.5 on the run line against the Reds. The Nationals are -142 to cover, and the Reds are +118.

Reds vs Nationals Over/Under

• The over/under for Reds-Nationals on July 22 is 9. The over is -102, and the under is -120.

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Reds vs Nationals Betting Trends

• The Reds have been chosen as favorites in 40 games this year and have walked away with the win 21 times (52.5%) in those games.
• This year Cincinnati has won 10 of 17 games when listed as at least -136 on the moneyline.
• The Reds and their opponents have gone over in 42 of their 95 games with a total set by sportsbooks this season.
• The Reds have posted a record of 50-45-0 against the spread this season.
• The Nationals have won 34 of the 76 games they were listed as the moneyline underdog this season (44.7%).
• Washington has gone 24-34 when playing as a moneyline underdog with odds of +116 or longer (41.4%).
• The Nationals have played in 94 games with an over/under set, and have combined with opponents to go over the total 54 times (54-38-2).
• The Nationals have gone 48-46-0 against the spread this season.

Reds Player Leaders

• Elly De La Cruz leads Cincinnati with 107 hits and a team-best slugging percentage of .483. He's batting .279 with an on-base percentage of .360.
• Among all qualifying hitters in baseball, he is 33rd in batting average, 35th in on-base percentage, and 31st in slugging.
• TJ Friedl leads Cincinnati with an OBP of .364 this season while batting .267 with 47 walks and 58 runs scored. He's slugging .392.
• Among all qualified hitters, he is 65th in batting average, 27th in on-base percentage and 113th in slugging percentage.
• Spencer Steer is batting .249 with a .396 slugging percentage and 41 RBI this year.
• Matt McLain has been key for Cincinnati with 71 hits, an OBP of .302 plus a slugging percentage of .347.
• McLain brings a seven-game hitting streak into this game. During his last 10 outings he is hitting .300 with two doubles, two home runs, five walks and four RBIs.

Nationals Player Leaders

• James Wood has racked up a team-high OBP (.379) and slugging percentage (.526), and paces the Nationals in hits (102, while batting .275).
• Including all the qualified hitters in MLB, his batting average ranks 48th, his on-base percentage ranks 10th, and he is 14th in slugging.
• C.J. Abrams has 21 doubles, four triples, 13 home runs and 25 walks while hitting .279. He's slugging .477 with an on-base percentage of .344.
• He is currently 33rd in batting average, 57th in on-base percentage and 37th in slugging percentage among all qualifying hitters.
• Luis Garcia is batting .260 with 20 doubles, seven home runs and 19 walks.
• Nathaniel Lowe has 14 doubles, two triples, 15 home runs and 37 walks while batting .228.

Reds vs Nationals Head to Head

• 7/21/2025: 10-8 WSH (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/4/2025: 4-1 WSH (Favorite: Reds, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 5/3/2025: 11-6 WSH (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 7/21/2024: 5-2 WSH (Favorite: Nationals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/20/2024: 5-4 WSH (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/19/2024: 8-5 WSH (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 3/31/2024: 6-5 CIN (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 3/30/2024: 7-6 WSH (Favorite: Reds, Spread: -1.5, Total: 10.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 3/28/2024: 8-2 CIN (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/6/2023: 6-3 WSH (Favorite: Reds, Spread: -1.5, Total: 10.5, Favorite Moneyline: -158, Underdog Moneyline: +134)

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