Cardinals vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for July 22

Odds updated as of 5:11 p.m.

The St. Louis Cardinals versus the Colorado Rockies is on the MLB schedule for Tuesday.

We've got you covered, in terms of the most important info about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Cardinals vs Rockies Game Info

• St. Louis Cardinals (52-49) vs. Colorado Rockies (24-76)
• Date: Tuesday, July 22, 2025
• Time: 8:40 p.m. ET
• Venue: Coors Field -- Denver, Colorado
• Coverage: COLR and FDSMW

Cardinals vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: STL: (-194) | COL: (+162)
• Spread: STL: -1.5 (-128) | COL: +1.5 (+106)
• Total: 11 -- Over: (-115) | Under: (-105)

Cardinals vs Rockies Probable Starting Pitchers

Probable Pitchers: Erick Fedde (Cardinals) - 3-9, 4.83 ERA vs Bradley Blalock (Rockies) - 0-2, 9.97 ERA

The Cardinals will give the nod to Erick Fedde (3-9, 4.83 ERA), who is eyeing win No. 4 on the season, and the Rockies will turn to Bradley Blalock (0-2, 9.97 ERA). When Fedde starts, his team is 9-8-0 against the spread this season. Fedde's team has won 25% of his starts when they are favored on the moneyline (1-3). The Rockies have a 1-3-0 ATS record in Blalock's four starts with a set spread. The Rockies were the moneyline underdog for four Blalock starts this season -- they lost all of the games.

Cardinals vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (58.2%)

Cardinals vs Rockies Moneyline

• St. Louis is a -194 favorite on the moneyline, while Colorado is a +162 underdog at home.

Cardinals vs Rockies Spread

• The Cardinals are 1.5-run road favorites on the runline against the Rockies. The Cardinals are -128 to cover, and the Rockies are +106.

Cardinals vs Rockies Over/Under

• Cardinals versus Rockies on July 22 has an over/under of 11 runs, with the odds on the over -115 and the under set at -105.

Bet on St. Louis Cardinals vs. Colorado Rockies on FanDuel today!

Cardinals vs Rockies Betting Trends

• The Cardinals have won in 24, or 54.5%, of the 44 contests they have been named as odds-on favorites in this year.
• St. Louis has played as a favorite of -194 or more just one time this year and came away with a win in that game.
• The Cardinals and their opponents have gone over in 52 of their 98 games with a total set by sportsbooks this season.
• The Cardinals have posted a record of 53-45-0 against the spread this season.
• The Rockies are 22-72 in games they were listed as the moneyline underdog (winning 23.4% of those games).
• When playing as a moneyline underdog with odds of +162 or longer, Colorado has gone 12-54 (18.2%).
• The Rockies have had an over/under set by bookmakers 98 times, and have combined with opponents to go over the total in 39 of those games (39-56-3).
• The Rockies have covered only 39.8% of their games this season, going 39-59-0 against the spread.

Cardinals Player Leaders

• Brendan Donovan leads St. Louis with an OBP of .364, plus a team-best slugging percentage of .425. He's batting .293 on the season.
• He ranks 12th in batting average, 27th in on-base percentage, and 80th in slugging among all qualified hitters in MLB.
• Nolan Arenado is hitting .244 with 15 doubles, a triple, 10 home runs and 26 walks. He's slugging .386 with an on-base percentage of .303.
• Among qualifiers, he is 113th in batting average, 127th in on-base percentage and 122nd in slugging percentage.
• Alec Burleson leads St. Louis with 88 hits. He is batting .289 this season and 29 of his hits have gone for extra bases.
• Willson Contreras has been key for St. Louis with 90 hits, an OBP of .341 plus a slugging percentage of .436.
• Contreras brings a two-game hitting streak into this game. During his last five outings he is batting .316 with three doubles, a home run, a walk and four RBIs.

Rockies Player Leaders

• Hunter Goodman has 93 hits with a .324 on-base percentage and a .518 slugging percentage, all club-highs for the Rockies. He's batting .278.
• Including all qualified hitters, he ranks 38th in batting average, while his on-base percentage ranks 86th and he is 16th in slugging.
• Jordan Beck paces his team with a .324 on-base percentage. He has a batting average of .271 while slugging .457.
• Including all qualifying players, his batting average puts him 53rd, his on-base percentage is 86th, and he is 53rd in slugging.
• Mickey Moniak is hitting .271 with 11 doubles, six triples, 14 home runs and 16 walks.
• Ryan McMahon has 15 doubles, a triple, 15 home runs and 47 walks while batting .218.

Cardinals vs Rockies Head to Head

• 7/21/2025: 6-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 11.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 9/26/2024: 10-8 COL (Favorite: Cardinals, Spread: -1.5, Total: 10.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 9/25/2024: 5-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 10.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 9/24/2024: 7-3 STL (Favorite: Cardinals, Spread: -1.5, Total: 10.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/9/2024: 5-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 6/8/2024: 6-5 COL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -205, Underdog Moneyline: +172)
• 6/7/2024: 8-5 STL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 6/6/2024: 3-2 COL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -230, Underdog Moneyline: +190)
• 8/6/2023: 1-0 COL (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 8/5/2023: 6-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -250, Underdog Moneyline: +205)

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