Mariners vs Brewers Prediction, Odds, Moneyline, Spread & Over/Under for July 22

Odds updated as of 5:11 p.m.

On Tuesday in MLB, the Seattle Mariners are up against the Milwaukee Brewers.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Mariners vs Brewers Game Info

• Seattle Mariners (53-47) vs. Milwaukee Brewers (60-40)
• Date: Tuesday, July 22, 2025
• Time: 9:40 p.m. ET
• Venue: T-Mobile Park -- Seattle, Washington
• Coverage: MLB Network, ROOT Sports NW, and FDSWI

Mariners vs Brewers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-126) | MIL: (+108)
• Spread: SEA: -1.5 (+172) | MIL: +1.5 (-210)
• Total: 6.5 -- Over: (-124) | Under: (+102)

Mariners vs Brewers Probable Starting Pitchers

Probable Pitchers: Logan Gilbert (Mariners) - 2-3, 3.39 ERA vs Jacob Misiorowski (Brewers) - 4-1, 2.81 ERA

This contest's pitching matchup is set, as the Mariners will send Logan Gilbert (2-3) to the mound, while Jacob Misiorowski (4-1) will get the nod for the Brewers. Gilbert's team is 5-7-0 against the spread this season in his starts. Gilbert's team has a record of 7-3 this season when he starts and they are the favorite on the moneyline. The Brewers have a 4-1-0 record against the spread in Misiorowski's starts. The Brewers have played when named the moneyline underdog for three of Misiorowski's starts this season, and they won each time.

Mariners vs Brewers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (55.8%)

Mariners vs Brewers Moneyline

• Milwaukee is a +108 underdog on the moneyline, while Seattle is a -126 favorite at home.

Mariners vs Brewers Spread

• The Mariners are hosting the Brewers and are favored by 1.5 runs (+172 to cover) on the runline. Milwaukee is -210 to cover.

Mariners vs Brewers Over/Under

• Mariners versus Brewers on July 22 has an over/under of 6.5 runs, with the odds on the over -124 and the under set at +102.

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Mariners vs Brewers Betting Trends

• The Mariners have been chosen as favorites in 63 games this year and have walked away with the win 35 times (55.6%) in those games.
• Seattle has a record of 27-18 when favored by -126 or more this year.
• Contests with the Mariners have gone over the total set by bookmakers in 53 of 97 chances this season.
• The Mariners are 42-55-0 against the spread in their 97 games that had a posted line this season.
• The Brewers have been the underdog on the moneyline 49 total times this season. They've gone 26-23 in those games.
• Milwaukee is 15-16 (winning 48.4% of its games) when playing as a moneyline underdog of +108 or longer.
• The Brewers have combined with opponents to go over the total 43 times this season for a 43-54-1 record against the over/under.
• The Brewers have gone 55-43-0 against the spread this season.

Mariners Player Leaders

• Cal Raleigh leads Seattle with 93 hits, batting .255 this season with 54 extra-base hits. He has an on-base percentage of .370 and a slugging percentage of .613.
• Among all qualified hitters in baseball, he is 90th in batting average, 19th in on-base percentage, and third in slugging.
• Raleigh will look for his third straight game with a hit in this contest. During his last five outings he is hitting .158 with four walks and an RBI.
• Julio Rodriguez is hitting .249 with 17 doubles, three triples, 14 home runs and 30 walks. He's slugging .408 with an on-base percentage of .312.
• He is 101st in batting average, 113th in on-base percentage and 96th in slugging in the majors.
• Randy Arozarena has collected 91 base hits, an OBP of .356 and a slugging percentage of .463 this season.
• J.P. Crawford leads the Mariners with an OPS of .771. He has a slash line of .285/.384/.387 this season.

Brewers Player Leaders

• Jackson Chourio has accumulated a team-high slugging percentage (.458) while leading the Brewers in hits (112). He's batting .267 and with an on-base percentage of .299.
• He ranks 65th in batting average, 133rd in on-base percentage and 51st in slugging percentage among all qualifying batters in the majors.
• Chourio hopes to build on a 15-game hitting streak in this matchup. During his last 10 games he is hitting .333 with two doubles, a home run, a walk and nine RBIs.
• Christian Yelich has 11 doubles, 19 home runs and 37 walks while batting .261. He's slugging .452 with an on-base percentage of .338.
• Including all qualifying players, he ranks 73rd in batting average, 64th in on-base percentage and 58th in slugging percentage.
• Brice Turang is hitting .278 with 15 doubles, six home runs and 40 walks.
• William Contreras has 18 doubles, six home runs and 56 walks while batting .244.

Mariners vs Brewers Head to Head

• 7/21/2025: 6-0 MIL (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 4/7/2024: 12-4 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/6/2024: 5-3 SEA (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 4/5/2024: 6-5 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 4/19/2023: 5-3 MIL (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 4/18/2023: 6-5 MIL (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/17/2023: 7-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -148, Underdog Moneyline: +126)

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