Rays vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for July 22

Odds updated as of 9:11 a.m.

The Tuesday slate in MLB includes a matchup between the Tampa Bay Rays and the Chicago White Sox.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info regarding this matchup.

Rays vs White Sox Game Info

• Tampa Bay Rays (52-49) vs. Chicago White Sox (36-65)
• Date: Tuesday, July 22, 2025
• Time: 7:35 p.m. ET
• Venue: George M. Steinbrenner Field -- Tampa, Florida
• Coverage: FDSSUN and CHSN

Rays vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TB: (-230) | CHW: (+190)
• Spread: TB: -1.5 (-110) | CHW: +1.5 (-110)
• Total: 8.5 -- Over: (-104) | Under: (-118)

Rays vs White Sox Probable Starting Pitchers

Probable Pitchers: Drew Rasmussen (Rays) - 7-5, 2.86 ERA vs Davis Martin (White Sox) - 2-7, 3.79 ERA

This contest's pitching matchup is set, as the Rays will send Drew Rasmussen (7-5) to the mound, while Davis Martin (2-7) will take the ball for the White Sox. Rasmussen and his team have a record of 9-8-0 against the spread when he starts. When Rasmussen starts a game and his team is the favorite on the moneyline, they have a record of 7-5. When Martin starts, the White Sox have gone 6-7-0 against the spread. The White Sox have a 3-10 record in Martin's 13 starts this season when they were the underdog on the moneyline.

Rays vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Rays win (69.4%)

Rays vs White Sox Moneyline

• Chicago is a +190 underdog on the moneyline, while Tampa Bay is a -230 favorite at home.

Rays vs White Sox Spread

• The White Sox are +1.5 on the run line against the Rays. The White Sox are -110 to cover, and the Rays are -110.

Rays vs White Sox Over/Under

• The Rays-White Sox contest on July 22 has been given an over/under of 8.5 runs. The over is set at -104 and the under at -118.

Bet on Tampa Bay Rays vs. Chicago White Sox on FanDuel today!

Rays vs White Sox Betting Trends

• The Rays have won in 30, or 58.8%, of the 51 contests they have been named as odds-on favorites in this year.
• Tampa Bay has played as a favorite of -230 or more just one time this year and came away with a win in that game.
• The Rays' games have gone over the total in 39 of their 98 opportunities.
• The Rays have posted a record of 45-53-0 against the spread this season.
• The White Sox have won 34.7% of the games this season they were the underdog on the moneyline (33-62).
• Chicago has gone 3-25 in games it has played as a moneyline underdog with odds of +190 or longer (10.7%).
• The White Sox have combined with opponents to go over the total 43 times this season for a 43-50-5 record against the over/under.
• The White Sox have a 54-44-0 record ATS this season.

Rays Player Leaders

• Yandy Diaz has an OPS of .826, fueled by an OBP of .352 and a team-best slugging percentage of .474 this season. He has a .293 batting average.
• Among qualified hitters in the majors, he ranks 12th in batting average, 45th in on-base percentage, and 38th in slugging.
• Diaz will look for his seventh straight game with a hit in this matchup. During his last 10 games he is hitting .333 with a double, two home runs, six walks and six RBIs.
• Junior Caminero leads Tampa Bay with 97 hits. He is batting .259 this season and has 45 extra-base hits. He's also slugging .513 with an on-base percentage of .299.
• Among all qualified, he ranks 78th in batting average, 133rd in on-base percentage and 18th in slugging percentage.
• Caminero has picked up a hit in five straight games. In his last five games he is batting .381 with a double, two home runs, a walk and five RBIs.
• Jonathan Aranda leads Tampa Bay with an OBP of .394 this season while batting .316 with 35 walks and 48 runs scored.
• Brandon Lowe has been key for Tampa Bay with 87 hits, an OBP of .320 plus a slugging percentage of .480.

White Sox Player Leaders

• Miguel Vargas is batting .223 with 25 doubles, two triples, 12 home runs and 38 walks. He's slugging .406 with an on-base percentage of .305.
• Including all qualifying hitters, he ranks 144th in batting average, while his on-base percentage is 125th and he is 97th in slugging.
• Vargas takes a three-game hitting streak into this game. During his last five outings he is hitting .300 with four doubles, two home runs, four walks and five RBIs.
• Andrew Benintendi is hitting .234 with 12 doubles, two triples, 11 home runs and 25 walks. He's slugging .429 with an on-base percentage of .303.
• Luis Robert is hitting .206 with nine doubles, 10 home runs and 34 walks.
• Chase Meidroth paces his team with a .333 on-base percentage.

Rays vs White Sox Head to Head

• 7/21/2025: 8-3 CHW (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 5/8/2024: 4-1 CHW (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 5/7/2024: 5-1 TB (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -270, Underdog Moneyline: +220)
• 5/6/2024: 8-2 TB (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/28/2024: 4-2 CHW (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 4/27/2024: 8-7 CHW (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 4/26/2024: 9-4 CHW (Favorite: Rays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -240, Underdog Moneyline: +194)
• 4/30/2023: 12-9 CHW (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 4/29/2023: 12-3 TB (Favorite: Rays, Spread: -1.5, Total: 9.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 4/28/2023: 3-2 TB (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -164, Underdog Moneyline: +138)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!