Reds vs Marlins Prediction, Odds, Moneyline, Spread & Over/Under for April 22

Odds updated as of 4:17 a.m.

The MLB schedule on Tuesday includes the Cincinnati Reds taking on the Miami Marlins.

We've got you covered, in terms of the most important info regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Reds vs Marlins Game Info

• Cincinnati Reds (11-12) vs. Miami Marlins (10-12)
• Date: Tuesday, April 22, 2025
• Time: 6:40 p.m. ET
• Venue: loanDepot park -- Miami, Florida
• Coverage: FDSFL and FDSOH

Reds vs Marlins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CIN: (-126) | MIA: (+108)
• Spread: CIN: -1.5 (+126) | MIA: +1.5 (-152)
• Total: 8.5 -- Over: (-105) | Under: (-115)

Reds vs Marlins Probable Starting Pitchers

Probable Pitchers: Nick Martínez (Reds) - 0-3, 6.00 ERA vs Edward Brany Cabrera (Marlins) - 0-1, 6.52 ERA

The Reds will look to Nick Martinez (0-3) versus the Marlins and Edward Brany Cabrera (0-1). Martínez's team is 1-3-0 against the spread this season in his starts. This will be Martinez's first game as the moneyline favorite this season. Cabrera has started two games with set spreads, and the Marlins failed to cover in both chances. The Marlins were named the moneyline underdog for two Cabrera starts this season -- they lost both.

Reds vs Marlins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (56.9%)

Reds vs Marlins Moneyline

• Looking at the moneyline for Reds-Marlins, Cincinnati is the favorite at -126, and Miami is +108 playing at home.

Reds vs Marlins Spread

• The Marlins are +1.5 on the spread (-152 to cover), and Cincinnati is +126 to cover the runline.

Reds vs Marlins Over/Under

• A total of 8.5 runs has been set for the Reds-Marlins game on April 22, with the over available at -105 and the under at -115.

Bet on Cincinnati Reds vs. Miami Marlins on FanDuel today!

Reds vs Marlins Betting Trends

• The Reds have been victorious in four of the seven contests they have been chosen as favorites in this season.
• This season Cincinnati has come away with a win two times in four chances when named as a favorite of at least -126 on the moneyline.
• Contests with the Reds have gone over the total set by sportsbooks in 12 of 23 chances this season.
• The Reds have an against the spread record of 13-10-0 in 23 games with a line this season.
• The Marlins have won eight of the 20 games they were the moneyline underdog this season (40%).
• In games it has played as a moneyline underdog with odds of +108 or longer, Miami has a 6-11 record (winning just 35.3% of its games).
• The Marlins have played in 22 games with a set over/under, and have combined with opponents to go over the total 15 times (15-7-0).
• The Marlins have collected a 12-10-0 record ATS this season.

Reds Player Leaders

• Elly De La Cruz leads Cincinnati with 22 hits, batting .242 this season with eight extra-base hits. He has an on-base percentage of .310 and a slugging percentage of .440.
• Among all qualified hitters in baseball, he ranks 85th in batting average, 102nd in on-base percentage, and 65th in slugging.
• De La Cruz will look for his seventh straight game with a hit in this contest. During his last 10 outings he is hitting .231 with three home runs, six walks and 10 RBI.
• TJ Friedl has an OPS of .746, fueled by an OBP of .358 and a team-best slugging percentage of .388 this season. He's batting .294.
• Among qualifying batters, he is 38th in batting average, 50th in on-base percentage and 97th in slugging percentage.
• Friedl heads into this matchup looking to extend his five-game hit streak. In his last five games he is batting .455 with a double, a triple, three walks and four RBI.
• Gavin Lux leads Cincinnati with an OBP of .419 this season while batting .315 with 13 walks and 10 runs scored.
• Lux brings a seven-game hitting streak into this game. During his last 10 games he is batting .424 with two doubles, a home run, nine walks and eight RBI.
• Matt McLain has four home runs, 10 RBI and a batting average of .212 this season.
• McLain brings a two-game hitting streak into this game. In his last five games he is batting .222 with a home run, five walks and four RBI.

Marlins Player Leaders

• Otto Lopez is hitting .235 with five doubles, two home runs and nine walks. He's slugging .370 with an on-base percentage of .311.
• Including all qualified hitters in the majors, his batting average places him 90th, his on-base percentage is 99th, and he is 107th in slugging.
• Xavier Edwards paces his team with a .319 slugging percentage. He has a batting average of .286 with an on-base percentage of .371.
• Including all qualified hitters, he is 44th in batting average, 40th in on-base percentage and 136th in slugging percentage.
• Eric Wagaman is leading the Marlins with 18 hits.
• Kyle Stowers' .388 on-base percentage paces his team.

Reds vs Marlins Head to Head

• 4/21/2025: 6-3 MIA (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/8/2024: 10-4 CIN (Favorite: Reds, Spread: -1.5, Total: 7.5, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 8/7/2024: 6-4 MIA (Favorite: Reds, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 8/6/2024: 8-2 CIN (Favorite: Reds, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 8/5/2024: 10-3 CIN (Favorite: Reds, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/14/2024: 3-2 MIA (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 7/13/2024: 10-6 CIN (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 7/12/2024: 7-4 CIN (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 8/8/2023: 3-2 MIA (Favorite: Marlins, Spread: -1.5, Total: 10, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 8/7/2023: 5-2 CIN (Favorite: Marlins, Spread: -1.5, Total: 10, Favorite Moneyline: -142, Underdog Moneyline: +120)

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