Angels vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for April 22

Odds updated as of 7:11 a.m.

MLB action on Tuesday includes the Los Angeles Angels facing the Pittsburgh Pirates.

We've got you covered, in terms of the most important information regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Angels vs Pirates Game Info

• Los Angeles Angels (11-10) vs. Pittsburgh Pirates (8-15)
• Date: Tuesday, April 22, 2025
• Time: 9:38 p.m. ET
• Venue: Angel Stadium -- Anaheim, California
• Coverage: FDSW and SportsNet PT

Angels vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAA: (-184) | PIT: (+154)
• Spread: LAA: -1.5 (+110) | PIT: +1.5 (-132)
• Total: 8.5 -- Over: (-112) | Under: (-108)

Angels vs Pirates Probable Starting Pitchers

Probable Pitchers: José Soriano (Angels) - 2-2, 3.16 ERA vs Bailey Falter (Pirates) - 1-2, 4.91 ERA

The Angels will look to Jose Soriano (2-2) against the Pirates and Bailey Falter (1-2). Soriano's team is 1-3-0 against the spread in his starts this season. Soriano's team is 1-1 this season when he starts and they're favored on the moneyline. The Pirates have a 1-3-0 record against the spread in Falter's starts. The Pirates were the moneyline underdog for two Falter starts this season -- they lost both.

Angels vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Angels win (55.8%)

Angels vs Pirates Moneyline

• The Angels vs Pirates moneyline has Los Angeles as a -184 favorite, while Pittsburgh is a +154 underdog on the road.

Angels vs Pirates Spread

• The Pirates are at +1.5 on the runline against the Angels. The Pirates are -132 to cover the spread, and the Angels are +110.

Angels vs Pirates Over/Under

• The Angels-Pirates contest on April 22 has been given an over/under of 8.5 runs. The over is set at -112 and the under at -108.

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Angels vs Pirates Betting Trends

• The Angels have won in three of the five contests they have been named as odds-on favorites in this year.
• These are the best odds of a victory sportsbooks have given Los Angeles this season, with a -184 moneyline set for this game.
• Contests with the Angels have gone over the total set by sportsbooks in 10 of 21 chances this season.
• The Angels have an against the spread mark of 11-10-0 in 21 games with a line this season.
• The Pirates have been the moneyline underdog 12 total times this season. They've finished 3-9 in those games.
• Pittsburgh has played as a moneyline underdog of +154 or longer in just two games this season, which it lost both.
• The Pirates have combined with opponents to go over the total 10 times this season for a 10-12-1 record against the over/under.
• The Pirates are 7-16-0 ATS this season.

Angels Player Leaders

• Mike Trout is batting .184 with a double, eight home runs and 11 walks. He has an on-base percentage of .289 while slugging .513.
• Among qualifying hitters in baseball, his batting average ranks 150th, his on-base percentage ranks 121st, and he is 30th in slugging.
• Nolan Schanuel leads the Angels with an OPS of .777. He has a slash line of .273/.349/.429 this season.
• His batting average ranks 62nd among qualified players, his on-base percentage 61st, and his slugging percentage 70th.
• Kyren Paris has collected 15 base hits, an OBP of .383 and a slugging percentage of .635 this season.
• Taylor Ward has five home runs, eight RBI and a batting average of .216 this season.

Pirates Player Leaders

• Oneil Cruz has 15 hits with a .354 on-base percentage, leading the Pirates in both statistics. He's batting .227 and slugging .485.
• Including all the qualifying hitters in the majors, he is 106th in batting average, 53rd in on-base percentage and 43rd in slugging percentage.
• Ke'Bryan Hayes is hitting .211 with a double, a triple, a home run and seven walks. He's slugging .289 with an on-base percentage of .277.
• Including all qualifying hitters, he is 123rd in batting average, 125th in on-base percentage and 153rd in slugging percentage.
• Enmanuel Valdez is batting .229 with three doubles, two triples, a home run and eight walks.
• Isiah Kiner-Falefa is hitting .268 with two doubles, a triple and five walks.

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