Diamondbacks vs Rays Prediction, Odds, Moneyline, Spread & Over/Under for April 22

Odds updated as of 7:11 a.m.

The Arizona Diamondbacks versus the Tampa Bay Rays is on the MLB schedule for Tuesday.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Diamondbacks vs Rays Game Info

• Arizona Diamondbacks (13-9) vs. Tampa Bay Rays (9-13)
• Date: Tuesday, April 22, 2025
• Time: 9:40 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: MLB Network, ARID, and FDSSUN

Diamondbacks vs Rays Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-156) | TB: (+132)
• Spread: ARI: -1.5 (+126) | TB: +1.5 (-152)
• Total: 9 -- Over: (-102) | Under: (-120)

Diamondbacks vs Rays Probable Starting Pitchers

Probable Pitchers: Brandon Pfaadt (Diamondbacks) - 3-1, 3.04 ERA vs Zack Littell (Rays) - 0-4, 5.48 ERA

The Diamondbacks will look to Brandon Pfaadt (3-1) versus the Rays and Zack Littell (0-4). Pfaadt's team is 3-1-0 against the spread in his starts this season. Pfaadt's team has a record of 3-1 this season when he starts and they are the favorite on the moneyline. In all of Littell's four starts that had a set spread, the Rays failed to cover. The Rays were the underdog on the moneyline for one Littell start this season -- they lost.

Diamondbacks vs Rays Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Diamondbacks win (56.6%)

Diamondbacks vs Rays Moneyline

• Arizona is the favorite, -156 on the moneyline, while Tampa Bay is a +132 underdog on the road.

Diamondbacks vs Rays Spread

• The Rays are +1.5 on the run line against the Diamondbacks. The Rays are -152 to cover, and the Diamondbacks are +126.

Diamondbacks vs Rays Over/Under

• The Diamondbacks-Rays contest on April 22 has been given an over/under of 9 runs. The over is set at -102 and the under at -120.

Bet on Arizona Diamondbacks vs. Tampa Bay Rays on FanDuel today!

Diamondbacks vs Rays Betting Trends

• The Diamondbacks have been victorious in 10, or 58.8%, of the 17 contests they have been chosen as favorites in this season.
• Arizona has a record of 2-1 in contests when sportsbooks favor them by -156 or more on the moneyline.
• The Diamondbacks and their opponents have hit the over in 10 of their 21 games with a total set by oddsmakers this season.
• The Diamondbacks are 11-10-0 against the spread in their 21 games with a line set by sportsbooks this season.
• The Rays have won 16.7% of the games this season they were the underdog on the moneyline (1-5).
• Tampa Bay has a 1-2 record (winning only 33.3% of its games) when it has played as a moneyline underdog of +132 or longer.
• In the 22 games oddsmakers have set an over/under for the Rays, they have combined with opponents to go over the total nine times (9-11-2).
• The Rays have covered just 36.4% of their games this season, going 8-14-0 against the spread.

Diamondbacks Player Leaders

• Corbin Carroll has 30 hits to go with a slugging percentage of .645, both of which are best among Arizona hitters this season. He has a .323 batting average and an on-base percentage of .394.
• Among qualifying hitters, he is 15th in batting average, his on-base percentage ranks 22nd, and he is fifth in slugging.
• Josh Naylor leads Arizona in OBP (.406) this season, fueled by 28 hits. He's batting .333 while slugging .548.
• He is 11th in batting average, 15th in on-base percentage and 18th in slugging among qualifying hitters.
• Geraldo Perdomo has 22 hits this season and has a slash line of .286/.392/.442.
• Pavin Smith has been key for Arizona with 21 hits, an OBP of .485 plus a slugging percentage of .691.

Rays Player Leaders

• Jonathan Aranda has totaled 22 hits with a .438 on-base percentage and a .677 slugging percentage, all club-bests for the Rays. He's batting .355.
• He is fourth in batting average, fourth in on-base percentage and third in slugging percentage among all qualifying hitters in the big leagues.
• Kameron Misner is batting .360 with four doubles, a triple, three home runs and four walks. He's slugging .660 with an on-base percentage of .404.
• Junior Caminero is hitting .269 with three doubles, five home runs and five walks.
• Yandy (Fernandez) Diaz is batting .222 with four doubles, three home runs and six walks.

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