Who Scores a Touchdown in Chargers vs Bills? NFL Prediction and Best Bets for Sunday

Who Scores a Touchdown: Chargers vs Bills

• Buffalo Bills -7.5
• James Cook Anytime Touchdown
• Josh Allen Anytime Touchdown
• Omarion Hampton Anytime Touchdown

Chargers at Bills is a real, decisive mismatch on paper, and the market has a specific storyline in mind — the site's own "Buffalo Stampede" parlay is banking on the NFL's No. 1 scoring offense to trample Los Angeles with four different touchdown scorers.

All NFL odds come from FanDuel Sportsbook's NFL betting odds and may change after this article is published.

Chargers vs Bills Prediction

Los Angeles Chargers at Buffalo Bills (Sun, 1:01 p.m. ET)

Buffalo Bills -7.5 (+100)

A -375 moneyline is a real, meaningful gap, with James Cook and Josh Allen both priced as the shortest touchdown favorites on the entire board at home.

Who Scores a Touchdown for the Bills

James Cook Anytime Touchdown (-180)

The shortest price on the entire touchdown board — the anchor of the site's own "Buffalo Stampede" parlay, which leans directly on Cook finding paydirt at home.

Josh Allen Anytime Touchdown (-135)

Allen's own real, dual-threat rushing ability near the goal line gives him the second-shortest price on the entire board — a genuine sign of his standalone scoring equity beyond just his passing production.

D.J. Moore Anytime Touchdown (+180)

Moore is priced right alongside Dalton Kincaid on this board, a real, genuine piece of the site's own "Buffalo Stampede" parlay for Sunday.

Who Scores a Touchdown for the Chargers

Omarion Hampton Anytime Touchdown (-120)

Hampton remains Los Angeles's clear, genuine touchdown threat even as a significant road underdog — the third-shortest price on the entire board, ahead of every other Chargers skill player.