Phillies vs Red Sox Prediction, Odds, Moneyline, Spread & Over/Under for July 22

Odds updated as of 8:12 a.m.

In MLB action on Tuesday, the Philadelphia Phillies play the Boston Red Sox.

We've got you covered, in terms of the vital information about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Phillies vs Red Sox Game Info

• Philadelphia Phillies (57-43) vs. Boston Red Sox (54-48)
• Date: Tuesday, July 22, 2025
• Time: 6:45 p.m. ET
• Venue: Citizens Bank Park -- Philadelphia, Pennsylvania
• Coverage: TBS, NBCS-PH, and NESN

Phillies vs Red Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-198) | BOS: (+166)
• Spread: PHI: -1.5 (+105) | BOS: +1.5 (-126)
• Total: 8.5 -- Over: (-112) | Under: (-108)

Phillies vs Red Sox Probable Starting Pitchers

Probable Pitchers: Cristopher Sanchez (Phillies) - 8-2, 2.43 ERA vs Richard Fitts (Red Sox) - 1-3, 4.28 ERA

The Phillies will give the ball to Cristopher Sanchez (8-2, 2.43 ERA), who is eyeing win No. 9 on the season, and the Red Sox will turn to Richard Fitts (1-3, 4.28 ERA). Sanchez's team is 11-8-0 against the spread in his starts this season. When Sanchez starts a game and his team is the favorite on the moneyline, they have a record of 13-3. The Red Sox have gone 2-5-0 against the spread when Fitts starts. The Red Sox were named the moneyline underdog for three Fitts starts this season -- they lost every game.

Phillies vs Red Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Phillies win (65.8%)

Phillies vs Red Sox Moneyline

• Philadelphia is the favorite, -198 on the moneyline, while Boston is a +166 underdog on the road.

Phillies vs Red Sox Spread

• The Red Sox are at +1.5 on the runline against the Phillies. The Red Sox are -126 to cover the spread, and the Phillies are +105.

Phillies vs Red Sox Over/Under

• Phillies versus Red Sox, on July 22, has an over/under of 8.5, with the over being -112 and the under -108.

Bet on Philadelphia Phillies vs. Boston Red Sox on FanDuel today!

Phillies vs Red Sox Betting Trends

• The Phillies have come away with 49 wins in the 75 contests they have been listed as the favorites in this season.
• Philadelphia has a record of 16-2 when favored by -198 or more this year.
• The Phillies and their opponents have gone over in 37 of their 94 games with a total set by sportsbooks this season.
• The Phillies are 47-47-0 against the spread in their 94 games with a line set by sportsbooks this season.
• The Red Sox have gone 14-19 in games they were listed as the moneyline underdog (winning 42.4% of those games).
• Boston is 1-2 (winning just 33.3% of its games) when it has played as a moneyline underdog of +166 or longer.
• The Red Sox have had an over/under set by bookmakers 101 times, and have combined with opponents to go over the total in 47 of those games (47-50-4).
• The Red Sox have covered 54.5% of their games this season, going 55-46-0 against the spread.

Phillies Player Leaders

• Kyle Schwarber has 91 hits, which is best among Philadelphia hitters this season, while batting .248 with 47 extra-base hits. He has an on-base percentage of .377 and a slugging percentage of .553.
• Among all qualifying hitters in baseball, he is 105th in batting average, 14th in on-base percentage, and 10th in slugging.
• Trea Turner has hit 11 homers this season while driving in 41 runs. He's batting .286 this season and slugging .425 with an on-base percentage of .343.
• His batting average is 22nd among qualified players, his on-base percentage 59th, and his slugging percentage 80th.
• Bryce Harper has 73 hits this season and a team-best OBP of .379.
• Nick Castellanos has 12 home runs, 53 RBI and a batting average of .270 this season.

Red Sox Player Leaders

• Jarren Duran has a team-best OBP (.323) and slugging percentage (.433). He's batting .257.
• Including all qualifying players, he ranks 84th in batting average, while his on-base percentage ranks 92nd and he is 73rd in slugging.
• Ceddanne Rafaela has collected 90 hits to lead his team. He has a batting average of .270 while slugging .471 with an on-base percentage of .311.
• Including all qualifying players, he is 55th in batting average, 119th in on-base percentage and 41st in slugging percentage.
• Wilyer Abreu is hitting .253 with 11 doubles, 20 home runs and 31 walks.
• Trevor Story has 13 doubles, 15 home runs and 19 walks while hitting .252.

Phillies vs Red Sox Head to Head

• 7/21/2025: 3-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 6/13/2024: 9-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 6/12/2024: 8-6 BOS (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 6/11/2024: 4-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 5/7/2023: 6-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 10, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/6/2023: 7-4 BOS (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/5/2023: 5-3 BOS (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -166, Underdog Moneyline: +140)

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