Phillies vs Rays Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 25

Odds updated as of 1:11 a.m.

The Philadelphia Phillies are among the MLB teams playing on Friday, up against the Tampa Bay Rays.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Phillies vs Rays Game Info

• Philadelphia Phillies (87-72) vs. Tampa Bay Rays (96-63)
• Date: Friday, September 25, 2026
• Time: 6:40 p.m. ET
• Venue: Citizens Bank Park -- Philadelphia, Pennsylvania
• Coverage: NBCS-PH and Rays.TV

Phillies vs Rays Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-166) | TB: (+140)
• Spread: PHI: -1.5 (+146) | TB: +1.5 (-176)
• Total: 6.5 -- Over: (-114) | Under: (-106)

Phillies vs Rays Probable Starting Pitchers

Probable Pitchers: Cristopher Sanchez (Phillies) - 18-6, 2.93 ERA vs Freddy Peralta (Rays) - 9-11, 4.56 ERA

The Phillies will give the ball to Cristopher Sanchez (18-6, 2.93 ERA), who is eyeing win No. 19 on the season, and the Rays will counter with Freddy Peralta (9-11, 4.56 ERA). When Sanchez starts, his team is 19-13-0 against the spread this season. When Sanchez starts a game and his team is the favorite on the moneyline, they have a record of 23-9. When Peralta starts, the Rays have gone 16-15-0 against the spread. The Rays have been the underdog on the moneyline in 12 of Peralta's starts this season, and they went 5-7 in those matchups.

Phillies vs Rays Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Phillies win (54.9%)

Phillies vs Rays Moneyline

• Looking at the moneyline for Rays-Phillies, Tampa Bay is the underdog at +140, and Philadelphia is -166 playing at home.

Phillies vs Rays Spread

• The Phillies are hosting the Rays and are favored by 1.5 runs on the spread. The Phillies are +146 to cover the runline, with the Rays being -176.

Phillies vs Rays Over/Under

• A total of 6.5 runs has been set for the Phillies-Rays game on Sept. 25, with the over available at -114 and the under at -106.

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Phillies vs Rays Betting Trends

• The Phillies have come away with 74 wins in the 115 contests they have been listed as the favorites in this season.
• This season Philadelphia has been victorious 36 times in 47 chances when named as a favorite of at least -166 on the moneyline.
• The Phillies and their opponents have gone over the total this season in 74 of their 154 opportunities.
• The Phillies have posted a record of 65-89-0 against the spread this season.
• The Rays have been the moneyline underdog 48 total times this season. They've finished 25-23 in those games.
• When playing as a moneyline underdog with odds of +140 or longer, Tampa Bay has a 2-1 record (winning 66.7% of its games).
• The Rays have had an over/under set by oddsmakers 157 times, and have combined with opponents to go over the total in 74 of those games (74-81-2).
• The Rays have collected an 83-74-0 record against the spread this season (covering 52.9% of the time).

Phillies Player Leaders

• Bryce Harper has 152 hits this season and a team-best OBP of .381. He has a .270 batting average and a slugging percentage of .486.
• Among all qualifying hitters, he ranks 42nd in batting average, his on-base percentage ranks eighth, and he is 20th in slugging.
• Luis Arraez leads Philadelphia in slugging percentage (.419) thanks to 46 extra-base hits. He's batting .310 with an on-base percentage of .345.
• Among qualifying batters, he is second in batting average, 48th in on-base percentage and 72nd in slugging percentage.
• Kyle Schwarber leads Philadelphia with 133 hits. He is batting .233 this season and 65 of his hits have gone for extra bases.
• Bryson Stott has 10 home runs, 66 RBI and a batting average of .249 this season.

Rays Player Leaders

• Junior Caminero is leading the Rays with 167 hits. He's batting .275 and slugging .522 with an on-base percentage of .360.
• Including all qualified hitters, he is 33rd in batting average, while his on-base percentage ranks 28th and he is fifth in slugging.
• Yandy Diaz paces his team with a .446 slugging percentage. He has a batting average of .292 with an on-base percentage of .358.
• Including all qualified hitters, his batting average places him ninth, his on-base percentage ranks 33rd, and he is 48th in slugging.
• Liam Hicks has put up an on-base percentage of .366, a team-best for the Rays.
• Chandler Simpson has 16 doubles, six triples and 26 walks while batting .308.

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