Mets vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 25

Odds updated as of 1:11 a.m.

The MLB's Friday schedule includes the New York Mets taking on the Washington Nationals.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Mets vs Nationals Game Info

• New York Mets (73-86) vs. Washington Nationals (75-84)
• Date: Friday, September 25, 2026
• Time: 6:45 p.m. ET
• Venue: Nationals Park -- Washington, District of Columbia
• Coverage: Nationals.TV and WPIX

Mets vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYM: (-134) | WSH: (+114)
• Spread: NYM: -1.5 (+128) | WSH: +1.5 (-154)
• Total: 8.5 -- Over: (+104) | Under: (-128)

Mets vs Nationals Probable Starting Pitchers

Probable Pitchers: TBA (Mets) vs Andrew Alvarez (Nationals) - 2-6, 0.00 ERA

The Nationals will look to Alvarez (2-6, 2.31), while the Mets' starter for this game is yet to be determined. The Nationals have a 6-10-0 record against the spread in Alvarez's starts. The Nationals have a 2-6 record in Alvarez's eight starts this season when they were the underdog on the moneyline.

Mets vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Nationals win (58.9%)

Mets vs Nationals Moneyline

• Washington is the underdog, +114 on the moneyline, while New York is a -134 favorite despite being on the road.

Mets vs Nationals Spread

• The Nationals are at +1.5 on the runline against the Mets. The Nationals are -154 to cover the spread, and the Mets are +128.

Mets vs Nationals Over/Under

• An over/under of 8.5 has been set for Mets-Nationals on Sept. 25, with the over being +104 and the under -128.

Bet on New York Mets vs. Washington Nationals on FanDuel today!

Mets vs Nationals Betting Trends

• The Mets have won in 40, or 52.6%, of the 76 contests they have been named as odds-on favorites in this year.
• This season New York has come away with a win 21 times in 42 chances when named as a favorite of at least -134 on the moneyline.
• The Mets' games have gone over the total in 73 of their 155 opportunities.
• The Mets have posted a record of 72-83-0 against the spread this season.
• The Nationals have won 51 of the 119 games they were the moneyline underdog this season (42.9%).
• Washington is 34-49 (winning 41% of its games) when playing as a moneyline underdog of +114 or longer.
• In the 155 games bookmakers have set an over/under for the Nationals, they have combined with opponents to go over the total 81 times (81-68-6).
• The Nationals have an 85-70-0 record ATS this season.

Mets Player Leaders

• Juan Soto is batting .274 with 11 doubles, two triples, 27 home runs and 77 walks. He has an on-base percentage of .393 while slugging .522.
• Carson Benge has 160 hits and an OBP of .338, both of which lead the Mets this season. He's batting .274 and slugging .419.
• He is 38th in batting average, 56th in on-base percentage and 72nd in slugging in MLB.
• Bo Bichette has hit 17 homers with a team-high .386 SLG this season.
• Francisco Lindor has been key for New York with 91 hits, an OBP of .308 plus a slugging percentage of .422.
• Lindor has hit safely in three straight games. During his last five outings he is hitting .136 with a double, two walks and an RBI.

Nationals Player Leaders

• C.J. Abrams has accumulated a slugging percentage of .500, a team-best for the Nationals. He's batting .262 with an on-base percentage of .338.
• He is 55th in batting average, 56th in on-base percentage and 15th in slugging percentage among all qualifying hitters in the big leagues.
• James Wood has 132 hits with a .385 OBP to lead his team in both. He has a batting average of .262 while slugging .505.
• Including all qualified hitters, he is 55th in batting average, fifth in on-base percentage and 14th in slugging percentage.
• Daylen Lile has 28 doubles, eight triples, 22 home runs and 40 walks while batting .247.
• Jacob Young is hitting .249 with 22 doubles, three triples, 10 home runs and 33 walks.

Mets vs Nationals Head to Head

• 8/16/2026: 4-3 NYM (Favorite: Mets, Spread: -1.5, Total: 8.5, Favorite Moneyline: -158, Underdog Moneyline: +146)
• 8/15/2026: 5-4 NYM (Favorite: Mets, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +124)
• 8/14/2026: 4-1 NYM (Favorite: Mets, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: +106)
• 5/21/2026: 2-1 NYM (Favorite: Mets, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 5/20/2026: 8-4 WSH (Favorite: Mets, Spread: -1.5, Total: 9.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/19/2026: 9-6 WSH (Favorite: Mets, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/18/2026: 16-7 NYM (Favorite: Mets, Spread: -1.5, Total: 10, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 4/30/2026: 5-4 WSH (Favorite: Mets, Spread: -1.5, Total: 7.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 4/29/2026: 14-2 WSH (Favorite: Mets, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 4/28/2026: 8-0 NYM (Favorite: Mets, Spread: -1.5, Total: 8, Favorite Moneyline: -188, Underdog Moneyline: +158)

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