Padres vs Cubs Prediction, Odds, Moneyline, Spread & Over/Under for NL Wild Card Game 1 on Sept. 30

Odds updated as of 5:11 a.m.

In MLB action on Wednesday, the San Diego Padres face the Chicago Cubs for Game 1 of the NL Wild Card Series.

We've got you covered, in terms of the vital information about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Padres vs Cubs Game Info

• San Diego Padres (91-71) vs. Chicago Cubs (89-73)
• Date: Wednesday, September 30, 2026
• Time: 10 p.m. ET
• Venue: Petco Park -- San Diego, California
• Coverage: NBCSN and Peacock

Padres vs Cubs Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-136) | CHC: (+116)
• Spread: SD: -1.5 (+164) | CHC: +1.5 (-200)
• Total: 7.5 -- Over: (+100) | Under: (-122)

Padres vs Cubs Probable Starting Pitchers

Probable Pitchers: Nick Pivetta (Padres) - 3-2, 2.86 ERA vs Kevin Gausman (Cubs) - 9-12, 4.51 ERA

The probable pitchers are Nick Pivetta (3-2, 2.86 ERA) for the Padres and Kevin Gausman (9-12, 4.51 ERA) for the Cubs. When Pivetta starts, his team is 5-3-0 against the spread this season. Pivetta has started five games with his team as the moneyline favorite and won each of them. The Cubs have a 13-19-0 record against the spread in Gausman's starts. The Cubs have a 2-8 record in Gausman's 10 starts this season when they were the moneyline underdog.

Padres vs Cubs Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (50.3%)

Padres vs Cubs Moneyline

• Chicago is the underdog, +116 on the moneyline, while San Diego is a -136 favorite at home.

Padres vs Cubs Spread

• The Cubs are at +1.5 on the runline against the Padres. The Cubs are -200 to cover the spread, and the Padres are +164.

Padres vs Cubs Over/Under

• An over/under of 7.5 has been set for Padres-Cubs on Sept. 30, with the over being +100 and the under -122.

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Padres vs Cubs Betting Trends

• The Padres have come away with 50 wins in the 81 contests they have been listed as the favorites in this season.
• This year San Diego has won 31 of 43 games when listed as at least -136 on the moneyline.
• Contests with the Padres have gone over the total set by bookmakers in 78 of 163 chances this season.
• The Padres have an against the spread record of 95-68-0 in 163 games with a line this season.
• The Cubs have been the underdog on the moneyline 46 total times this season. They've finished 23-23 in those games.
• Chicago has an 8-4 record (winning 66.7% of its games) when playing as a moneyline underdog of +116 or longer.
• The Cubs have combined with opponents to hit the over on the total 90 times this season for a 90-68-0 record against the over/under.
• The Cubs are 74-84-0 against the spread this season.

Padres Player Leaders

• Fernando Tatis Jr. has an OPS of .828, fueled by an OBP of .358 and a team-best slugging percentage of .470 this season. He has a .289 batting average.
• Among all qualified batters, he ranks 13th in batting average, his on-base percentage ranks 36th, and he is 34th in slugging.
• Jackson Merrill is batting .254 with 26 doubles, five triples, 26 home runs and 41 walks, while slugging .440 with an on-base percentage of .303.
• Among qualifying hitters, his batting average ranks him 74th, his on-base percentage 113th, and his slugging percentage 56th.
• Merrill enters this game looking to extend his four-game hit streak. During his last five outings he is hitting .333 with a double, a walk and three RBIs.
• Manny Machado has collected 128 base hits, an OBP of .303 and a slugging percentage of .407 this season.
• Machado takes a three-game hitting streak into this game. During his last five outings he is hitting .278 with a double, two home runs, a walk and six RBIs.
• Xander Bogaerts has 13 home runs, 57 RBI and a batting average of .231 this season.
• Bogaerts heads into this game on a three-game hitting streak. In his last five games he is hitting .357 with two home runs, four walks and two RBIs.

Cubs Player Leaders

• Pete Crow-Armstrong has put up an on-base percentage of .372, a slugging percentage of .570, and has 175 hits, all club-highs for the Cubs (while batting .280).
• Including all qualifying players, he is 26th in batting average, while his on-base percentage ranks 14th and he is second in slugging.
• Alex Bregman is hitting .265 with 33 doubles, two triples, 28 home runs and 76 walks. He's slugging .464 with an on-base percentage of .355.
• Including all qualifying hitters, his batting average puts him 48th, his on-base percentage ranks 39th, and he is 39th in slugging.
• Seiya Suzuki is batting .270 with 31 doubles, a triple, 26 home runs and 81 walks.
• Nico Hoerner has 29 doubles, a triple, eight home runs and 43 walks while hitting .263.

Padres vs Cubs Head to Head

• 9/29/2026: 8-0 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 7/1/2026: 23-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 12, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/30/2026: 9-7 CHC (Favorite: Cubs, Spread: -1.5, Total: 11.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 6/29/2026: 3-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 11.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 4/29/2026: 5-4 CHC (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/28/2026: 8-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: +100)
• 4/27/2026: 9-7 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 10/2/2025: 3-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 10/1/2025: 3-0 SD (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/30/2025: 3-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -126, Underdog Moneyline: +108)

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