Mariners vs Angels Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 26

Odds updated as of 4:11 a.m.

The MLB's Saturday schedule includes the Seattle Mariners facing the Los Angeles Angels.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Mariners vs Angels Game Info

• Seattle Mariners (74-86) vs. Los Angeles Angels (62-98)
• Date: Saturday, September 26, 2026
• Time: 9:40 p.m. ET
• Venue: T-Mobile Park -- Seattle, Washington
• Coverage: Mariners.TV and ABTV

Mariners vs Angels Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-198) | LAA: (+166)
• Spread: SEA: -1.5 (+116) | LAA: +1.5 (-140)
• Total: 7.5 -- Over: (-110) | Under: (-110)

Mariners vs Angels Probable Starting Pitchers

Probable Pitchers: Kade Anderson (Mariners) - 2-2, 4.18 ERA vs Ryan Johnson (Angels) - 5-9, 4.93 ERA

The Mariners will call on Kade Anderson (2-2) against the Angels and Ryan Johnson (5-9). Anderson's team is 1-4-0 against the spread in his starts this season. Anderson's team has a record of 3-2 this season when he starts and they are the favorite on the moneyline. When Johnson starts, the Angels are 8-10-0 against the spread. The Angels have a 7-11 record in Johnson's 18 starts this season when they were the underdog on the moneyline.

Mariners vs Angels Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (62.7%)

Mariners vs Angels Moneyline

• Seattle is a -198 favorite on the moneyline, while Los Angeles is a +166 underdog on the road.

Mariners vs Angels Spread

• The Angels are at +1.5 on the runline against the Mariners. The Angels are -140 to cover the spread, and the Mariners are +116.

Mariners vs Angels Over/Under

• The over/under for Mariners-Angels on Sept. 26 is 7.5. The over is -110, and the under is -110.

Bet on Seattle Mariners vs. Los Angeles Angels on FanDuel today!

Mariners vs Angels Betting Trends

• The Mariners have come away with 60 wins in the 123 contests they have been listed as the favorites in this season.
• This season Seattle has been victorious four times in seven chances when named as a favorite of at least -198 on the moneyline.
• The Mariners and their opponents have gone over the total this season in 84 of their 158 opportunities.
• The Mariners have posted a record of 56-102-0 against the spread this season.
• The Angels have been the underdog on the moneyline 128 total times this season. They've finished 46-82 in those games.
• Los Angeles is 5-5 (winning 50% of its games) when playing as a moneyline underdog of +166 or longer.
• The Angels have combined with opponents to hit the over on the total 68 times this season for a 68-88-3 record against the over/under.
• The Angels are 84-75-0 against the spread this season.

Mariners Player Leaders

• Randy Arozarena has an OPS of .862, fueled by an OBP of .380 to go with a slugging percentage of .482. He has a .280 batting average, as well.
• He ranks 23rd in batting average, ninth in on-base percentage, and 26th in slugging among all qualified batters in MLB.
• Arozarena will look for his fourth straight game with a hit in this contest. During his last five outings he is batting .250 with a double, a triple, five walks and an RBI.
• Josh Naylor is hitting .263 with 22 doubles, 10 home runs and 44 walks, while slugging .351 with an on-base percentage of .319.
• Among qualifying hitters, his batting average places him 54th, his on-base percentage 89th, and his slugging percentage 128th.
• Julio Rodriguez is batting .249 with a .404 slugging percentage and 71 RBI this year.
• Dominic Canzone leads Seattle in total hits (124) this season while batting .264 with 54 extra-base hits.

Angels Player Leaders

• Zach Neto has racked up a slugging percentage of .440 and has 148 hits, both team-high numbers for the Angels. He's batting .241 and with an on-base percentage of .329.
• Including all qualified hitters, he ranks 96th in batting average, while his on-base percentage is 70th and he is 54th in slugging.
• Neto hopes to build on a four-game hitting streak in this matchup. In his last five games he is hitting .333 with two doubles, a home run, four walks and three RBIs.
• Mike Trout's .384 on-base percentage paces his team. He has a batting average of .244 while slugging .424.
• His batting average ranks 88th among all qualified players, his on-base percentage is seventh, and he is 69th in slugging.
• Vaughn Grissom is batting .244 with 22 doubles, 13 home runs and 31 walks.
• Wade Meckler is hitting .306 with 15 doubles, a triple, three home runs and 32 walks.

Mariners vs Angels Head to Head

• 9/25/2026: 7-5 LAA (Favorite: Mariners, Spread: -1.5, Total: 6.5, Favorite Moneyline: -118, Underdog Moneyline: +100)
• 9/24/2026: 6-4 LAA (Favorite: Mariners, Spread: -1.5, Total: 6.5, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 9/16/2026: 7-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/15/2026: 2-1 LAA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 9/14/2026: 6-4 LAA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 7/2/2026: 1-0 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 6/30/2026: 8-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 6/29/2026: 6-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 4/5/2026: 8-7 LAA (Favorite: Mariners, Spread: -1.5, Total: 9, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 4/4/2026: 1-0 LAA (Favorite: Mariners, Spread: -1.5, Total: 9.5, Favorite Moneyline: -156, Underdog Moneyline: +132)

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