Kentucky vs South Alabama Prediction, Odds, Picks, Best Bets for Week 4 2026

The Saturday slate in college football includes a matchup between the Kentucky Wildcats and the South Alabama Jaguars.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

Kentucky vs South Alabama Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Kentucky: (-1786) | South Alabama: (+920)
• Spread: Kentucky: -20.5 (-110) | South Alabama: +20.5 (-110)
• Total: 54.5 -- Over: (-110) | Under: (-110)

Kentucky vs South Alabama Betting Trends

• Kentucky has posted two wins against the spread this year.
• Kentucky has yet to lose ATS (1-0) as a 20.5-point favorite or greater this season.
• Two of Kentucky's three games have gone over the point total.
• South Alabama owns two wins against the spread this year.
• South Alabama has played two games (out of three) which finished over the total this season.

Kentucky vs South Alabama Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Wildcats win (90.7%)

Kentucky vs South Alabama Point Spread

Kentucky is favored by 20.5 points over South Alabama. Kentucky is -110 to cover the spread, with South Alabama being -110.

Kentucky vs South Alabama Over/Under

Kentucky versus South Alabama on Sept. 26 has an over/under of 54.5 points, with the over -110 and the under -110.

Kentucky vs South Alabama Moneyline

The moneyline numbers for Kentucky vs. South Alabama reveal Kentucky as the favorite (-1786) and South Alabama as the underdog (+920).

Kentucky vs. South Alabama Points Insights

Kentucky vs. South Alabama Game Info

• Game day: Saturday, September 26, 2026
• Game time: 12:45 p.m. ET
• TV channel: SEC Network
• Location: Lexington, Kentucky
• Stadium: Kroger Field

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Check out even more in-depth Kentucky vs. South Alabama analysis on FanDuel Research.