Guardians vs Tigers Prediction, Odds, Moneyline, Spread & Over/Under for May 19

Odds updated as of 1:11 a.m.

The Cleveland Guardians will take on the Detroit Tigers in MLB action on Tuesday.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Guardians vs Tigers Game Info

• Cleveland Guardians (27-22) vs. Detroit Tigers (20-28)
• Date: Tuesday, May 19, 2026
• Time: 6:40 p.m. ET
• Venue: Comerica Park -- Detroit, Michigan
• Coverage: DSN and CleGuardians.TV

Guardians vs Tigers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-124) | DET: (+106)
• Spread: CLE: -1.5 (+140) | DET: +1.5 (-170)
• Total: 8 -- Over: (-110) | Under: (-110)

Guardians vs Tigers Probable Starting Pitchers

Probable Pitchers: Parker Messick (Guardians) - 5-1, 2.35 ERA vs Keider Montero (Tigers) - 2-3, 3.65 ERA

The Guardians will look to Parker Messick (5-1) versus the Tigers and Keider Montero (2-3). Messick's team is 7-2-0 against the spread this season in his starts. Messick's team is 4-2 this season when he starts and they are the moneyline favorite. The Tigers have a 5-3-0 ATS record in Montero's eight starts with a set spread. The Tigers have been the moneyline underdog in four of Montero's starts this season, and they went 2-2 in those games.

Guardians vs Tigers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Tigers win (50%)

Guardians vs Tigers Moneyline

• Looking at the moneyline for Tigers-Guardians, Detroit is the underdog at +106, and Cleveland is -124 playing on the road.

Guardians vs Tigers Spread

• The Tigers are +1.5 on the run line against the Guardians. The Tigers are -170 to cover, and the Guardians are +140.

Guardians vs Tigers Over/Under

• The over/under for Guardians-Tigers on May 19 is 8. The over is -110, and the under is -110.

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Guardians vs Tigers Betting Trends

• The Guardians have come away with 14 wins in the 25 contests they have been listed as the favorites in this season.
• This year Cleveland has won 10 of 19 games when listed as at least -124 on the moneyline.
• Contests with the Guardians have gone over the total set by bookmakers in 25 of 46 chances this season.
• The Guardians have posted a record of 25-21-0 against the spread this season.
• The Tigers have gone 7-12 in games they were listed as the moneyline underdog (winning 36.8% of those games).
• In games it has played as a moneyline underdog with odds of +106 or longer, Detroit has a record of 2-6 (25%).
• In the 47 games oddsmakers have set an over/under for the Tigers, they have combined with opponents to go over the total 21 times (21-25-1).
• The Tigers have gone 23-24-0 against the spread this season.

Guardians Player Leaders

• Jose Ramirez is hitting .240 with 10 doubles, eight home runs and 36 walks. He has an on-base percentage of .369 while slugging .430.
• Among qualifying batters in baseball, he is 106th in batting average, 34th in on-base percentage, and 66th in slugging.
• Ramirez will look for his fifth straight game with a hit in this matchup. In his last five games he is hitting .529 with two doubles, two home runs, five walks and six RBIs.
• Chase DeLauter has hit seven homers this season while driving in 30 runs. He's batting .275 this season and slugging .481 with an on-base percentage of .362.
• His batting average is 43rd among qualified players, his on-base percentage 41st, and his slugging percentage 35th.
• Brayan Rocchio leads the Guardians with an OPS of .787. He has a slash line of .288/.375/.412 this season.
• Rocchio has logged a hit or more in three games in a row. During his last five outings he is hitting .357 with a triple, a home run, four walks and four RBIs.
• Angel Martinez has 40 hits, which leads Cleveland hitters this season, while batting .270 with 17 extra-base hits.
• Martinez enters this game on a seven-game hitting streak. During his last 10 games he is batting .268 with a double, four home runs, two walks and nine RBIs.

Tigers Player Leaders

• Kevin McGonigle is hitting .291 with 12 doubles, two triples, two home runs and 28 walks. He's slugging .419 with an on-base percentage of .396.
• Including all the qualified hitters in MLB, his batting average places him 26th, his on-base percentage is 10th, and he is 72nd in slugging.
• McGonigle takes a three-game hitting streak into this matchup. During his last five outings he is hitting .211 with two walks.
• Riley Greene has 56 hits with a .422 OBP while slugging .485. Those stats all lead his team. He also has a batting average of .327.
• Including all qualified hitters, he is fourth in batting average, third in on-base percentage and 34th in slugging percentage.
• Dillon Dingler is hitting .247 with nine doubles, eight home runs and 13 walks.
• Matt Vierling is hitting .211 with nine doubles, four home runs and 12 walks.

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