Dodgers vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 20

Odds updated as of 6:12 a.m.

MLB action on Saturday includes the Los Angeles Dodgers playing the San Francisco Giants.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Dodgers vs Giants Game Info

• Los Angeles Dodgers (87-67) vs. San Francisco Giants (76-78)
• Date: Saturday, September 20, 2025
• Time: 9:10 p.m. ET
• Venue: Dodger Stadium -- Los Angeles, California
• Coverage: SportsNet LA and NBCS-BA

Dodgers vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAD: (-235) | SF: (+194)
• Spread: LAD: -1.5 (-110) | SF: +1.5 (-111)
• Total: 8.5 -- Over: (-115) | Under: (-105)

Dodgers vs Giants Probable Starting Pitchers

Probable Pitchers: Tyler Glasnow (Dodgers) - 3-3, 3.06 ERA vs Kai-Wei Teng (Giants) - 2-4, 6.41 ERA

The probable starters are Tyler Glasnow (3-3) for the Dodgers and Kai-Wei Teng (2-4) for the Giants. Glasnow's team is 4-12-0 against the spread in his starts this season. Glasnow's team has a record of 8-8 this season when he starts and they are the favorite on the moneyline. The Giants have a 2-4-0 ATS record in Teng's six starts with a set spread. The Giants were the moneyline underdog for five Teng starts this season -- they lost each time.

Dodgers vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Dodgers win (58.8%)

Dodgers vs Giants Moneyline

• Los Angeles is the favorite, -235 on the moneyline, while San Francisco is a +194 underdog on the road.

Dodgers vs Giants Spread

• The Dodgers are favored by 1.5 runs at home against the Giants. The Dodgers are -110 to cover the spread, while the Giants are -111.

Dodgers vs Giants Over/Under

• The over/under for the Dodgers versus Giants game on Sept. 20 has been set at 8.5, with -115 odds on the over and -105 odds on the under.

Bet on Los Angeles Dodgers vs. San Francisco Giants on FanDuel today!

Dodgers vs Giants Betting Trends

• The Dodgers have been chosen as favorites in 135 games this year and have walked away with the win 77 times (57%) in those games.
• Los Angeles has a record of 21-7 when favored by -235 or more this year.
• The Dodgers and their opponents have hit the over in 73 of their 152 games with a total set by oddsmakers this season.
• In 152 games with a line this season, the Dodgers have a mark of 65-87-0 against the spread.
• The Giants have a 27-35 record in games they were listed as the moneyline underdog (winning 43.5% of those games).
• San Francisco has yet to play as a moneyline underdog of +194 or longer.
• The Giants have had an over/under set by bookmakers 153 times, and have combined with opponents to go over the total in 73 of those games (73-72-8).
• The Giants have a 72-81-0 record against the spread this season (covering 47.1% of the time).

Dodgers Player Leaders

• Shohei Ohtani has 165 hits and an OBP of .394 to go with a slugging percentage of .619. All three of those stats are best among Los Angeles hitters this season. He has a .283 batting average, as well.
• Among the qualifying batters in the majors, his batting average ranks 20th, his on-base percentage ranks third, and he is second in slugging.
• Ohtani has picked up at least one hit in seven games in a row. During his last 10 outings he is hitting .333 with three doubles, four home runs, eight walks and eight RBIs.
• Mookie Betts is batting .260 with 22 doubles, two triples, 20 home runs and 58 walks, while slugging .413 with an on-base percentage of .328.
• Among qualifiers, he is 66th in batting average, 74th in on-base percentage and 87th in slugging percentage.
• Freddie Freeman is batting .293 with a .492 slugging percentage and 84 RBI this year.
• Andy Pages has been key for Los Angeles with 154 hits, an OBP of .321 plus a slugging percentage of .470.

Giants Player Leaders

• Rafael Devers has put up an on-base percentage of .371 and has 145 hits, both team-high numbers for the Giants. He's batting .251 and slugging .466.
• He ranks 90th in batting average, 11th in on-base percentage and 43rd in slugging percentage among all qualified hitters in the majors.
• Jung Hoo Lee is hitting .261 with 30 doubles, 11 triples, eight home runs and 47 walks. He's slugging .403 with an on-base percentage of .325.
• Including all qualified players, he is 61st in batting average, 82nd in on-base percentage and 97th in slugging percentage.
• Willy Adames has 21 doubles, two triples, 28 home runs and 76 walks while hitting .226.
• Heliot Ramos is slugging .394 to pace his team.

Dodgers vs Giants Head to Head

• 9/19/2025: 6-3 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 9/18/2025: 2-1 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 9/14/2025: 10-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 9/13/2025: 13-7 LAD (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/12/2025: 5-1 SF (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 7/13/2025: 5-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/12/2025: 2-1 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 7/11/2025: 8-7 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 6/15/2025: 5-4 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 6/14/2025: 11-5 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -180, Underdog Moneyline: +152)

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