Cubs vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for June 6

Odds updated as of 10:12 p.m.

MLB action on Saturday includes the Chicago Cubs taking on the San Francisco Giants.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Cubs vs Giants Game Info

• Chicago Cubs (33-31) vs. San Francisco Giants (26-38)
• Date: Saturday, June 6, 2026
• Time: 2:20 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MARQ and NBCS-BA

Cubs vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-138) | SF: (+118)
• Spread: CHC: -1.5 (+155) | SF: +1.5 (-188)
• Total: 8.5 -- Over: (+100) | Under: (-122)

Cubs vs Giants Probable Starting Pitchers

Probable Pitchers: Ben Brown (Cubs) - 2-2, 1.92 ERA vs Landen Roupp (Giants) - 5-6, 4.22 ERA

The Cubs will call on Ben Brown (2-2) versus the Giants and Landen Roupp (5-6). Brown and his team have a record of 3-2-0 against the spread when he starts. Brown's team is 2-1 this season when he starts and they are the moneyline favorite. The Giants have a 4-8-0 record against the spread in Roupp's starts. The Giants are 4-4 in Roupp's eight starts this season that they were the underdog on the moneyline.

Cubs vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (60.5%)

Cubs vs Giants Moneyline

• Chicago is the favorite, -138 on the moneyline, while San Francisco is a +118 underdog on the road.

Cubs vs Giants Spread

• The Giants are +1.5 on the run line against the Cubs. The Giants are -188 to cover, and the Cubs are +155.

Cubs vs Giants Over/Under

• Cubs versus Giants, on June 6, has an over/under of 8.5, with the over being +100 and the under -122.

Bet on Chicago Cubs vs. San Francisco Giants on FanDuel today!

Cubs vs Giants Betting Trends

• The Cubs have been chosen as favorites in 41 games this year and have walked away with the win 22 times (53.7%) in those games.
• Chicago has a record of 13-9 in contests when sportsbooks favor them by -138 or more on the moneyline.
• The Cubs and their opponents have gone over in 35 of their 62 games with a total set by sportsbooks this season.
• The Cubs have posted a record of 24-38-0 against the spread this season.
• The Giants have a 15-27 record in games they were the underdog on the moneyline (winning 35.7% of those games).
• When it has played as a moneyline underdog with odds of +118 or longer, San Francisco has an 8-9 record (winning 47.1% of its games).
• In the 63 games bookmakers have set an over/under for the Giants, they have combined with opponents to go over the total 32 times (32-27-4).
• The Giants have collected a 26-37-0 record against the spread this season (covering 41.3% of the time).

Cubs Player Leaders

• Nico Hoerner is batting .250 with 14 doubles, four home runs and 29 walks. He has an on-base percentage of .333 while slugging .353.
• Among all qualified hitters in the majors, he is 82nd in batting average, 79th in on-base percentage, and 127th in slugging.
• Ian Happ has 53 hits, which ranks first among Chicago batters this season. He's batting .235 with 28 extra-base hits. He's also slugging .487 with an on-base percentage of .350.
• His batting average is 114th among qualified players, his on-base percentage 56th, and his slugging percentage 31st.
• Michael Busch leads Chicago in OBP (.368) this season, fueled by 55 hits.
• Pete Crow-Armstrong is batting .248 with a .335 OBP and 30 RBI for Chicago this season.
• Crow-Armstrong has hit safely in 10 straight games. In his last 10 games he is hitting .366 with three doubles, three home runs, three walks and seven RBIs.

Giants Player Leaders

• Luis Arraez has accumulated a .364 on-base percentage and a .439 slugging percentage, both team-high averages for the Giants. He's batting .326.
• He ranks third in batting average, 35th in on-base percentage and 64th in slugging percentage among all qualifying hitters in the big leagues.
• Arraez enters this matchup on a six-game hitting streak. During his last 10 outings he is batting .368 with three doubles, a triple, two walks and seven RBIs.
• Casey Schmitt's 65 hits lead his team. He has a batting average of .293 while slugging .559 with an on-base percentage of .325.
• Including all qualified hitters, his batting average places him 20th, his on-base percentage is 94th, and he is sixth in slugging.
• Jung Hoo Lee is batting .321 with 14 doubles, two triples, three home runs and 10 walks.
• Willy Adames has 18 doubles, a triple, 11 home runs and 16 walks while batting .250.

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