Commanders vs Lions Prediction, Picks, Odds & Best Bets Today Saturday August 22

NFL Betting Picks in Summary

• Under 37.5
• 1st Half Under 20.5
• Lions -1.5

Washington and Detroit open Saturday's slate at noon, and the story here is squarely about who isn't playing rather than who is.

All NFL preseason odds come from FanDuel Sportsbook's NFL betting odds and may change after this article is published.

Depth Chart Notes

Detroit: Jared Goff will not play. Head coach Dan Campbell confirmed Joshua Dobbs will start, splitting the workload evenly with rookie Luke Altmyer, who started last week and went 13-of-22 for 130 yards with a touchdown and two interceptions in his own preseason debut. The competition between the two remains genuinely open.

Washington: No specific quarterback plan was available at the time of writing — worth confirming Washington's starter before kickoff.

NFL Predictions and Picks for Preseason Week 2

Washington Commanders at Detroit Lions (Sat, 12 p.m. ET)

Under 37.5 (-105)

Two quarterbacks splitting reps evenly, rather than one getting a real extended rhythm, tends to produce a choppier offense overall. Altmyer's own debut included two interceptions, which points toward a genuinely turnover-prone, stop-start kind of game rather than a clean, high-scoring one.

1st Half Under 20.5 (-138)

The market itself already leans this way, and the split-QB workload logic applies even more directly to a single half than the full game.

Lions -1.5 (-105)

A modest home favorite number with no specific reporting to argue against it — Detroit's overall roster depth is a reasonable enough edge on its own at this short a line.