College Football Predictions: Missouri vs Kansas Prediction, Picks, Odds & Best Bets

College Football Betting Picks in Summary
- Missouri -4.5
- Over 51.5
- Jamal Roberts Over 80.5 Rushing Yards
Kansas travels to Missouri in a genuinely competitive matchup — a modest 4.5-point spread with both starting quarterbacks carrying real, comparable passing volume.
All college football odds come from FanDuel Sportsbook's college football betting odds and may change after this article is published.
College Football Predictions and Picks
Kansas at Missouri (Thu, 8:00 p.m. ET)
Missouri -4.5 (-110)
Spread
Missouri's own projected yardage output (394.5) sits ahead of Kansas's (357.5), a modest but real edge that lines up with the home favorite number without needing a blowout to justify it.
Over 51.5 (-110)
Total
Both offenses carry real, sizable yardage projections — a combined 752 yards between the two team totals — pointing toward a genuine back-and-forth scoring game rather than a defensive grind.
Jamal Roberts Over 80.5 Rushing Yards (-158)
Rushing Yards
Roberts is priced to clear 70 yards on his own at -230, a real sign Missouri plans to lean on its ground game as a central part of the gameplan in a genuinely competitive matchup.
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The above author is a FanDuel employee and is not eligible to compete in public daily fantasy contests or place sports betting wagers on FanDuel. The advice provided by the author does not necessarily represent the views of FanDuel. Taking the author's advice will not guarantee a successful outcome. You should use your own judgment when participating in daily fantasy contests or placing sports wagers.



