Cardinals vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for July 10

Odds updated as of 7:12 a.m.

The St. Louis Cardinals will face the Washington Nationals in MLB action on Thursday.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Cardinals vs Nationals Game Info

• St. Louis Cardinals (49-44) vs. Washington Nationals (38-54)
• Date: Thursday, July 10, 2025
• Time: 7:45 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: FDSMW and MASN

Cardinals vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: STL: (-142) | WSH: (+120)
• Spread: STL: -1.5 (+146) | WSH: +1.5 (-178)
• Total: 9 -- Over: (-100) | Under: (-122)

Cardinals vs Nationals Probable Starting Pitchers

Probable Pitchers: Miles Mikolas (Cardinals) - 4-6, 5.26 ERA vs Mike Soroka (Nationals) - 3-6, 5.40 ERA

The probable starters are Miles Mikolas (4-6) for the Cardinals and Mike Soroka (3-6) for the Nationals. Mikolas and his team are 8-9-0 ATS this season when he starts. Mikolas' team has been victorious in 50% of the games he's started as the moneyline favorite with a record of 2-2. The Nationals have a 5-7-0 record against the spread in Soroka's starts. The Nationals have been the underdog on the moneyline in 11 of Soroka's starts this season, and they went 3-8 in those games.

Cardinals vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (61.9%)

Cardinals vs Nationals Moneyline

• Washington is the underdog, +120 on the moneyline, while St. Louis is a -142 favorite at home.

Cardinals vs Nationals Spread

• The Cardinals are 1.5-run home favorites on the runline against the Nationals. The Cardinals are +146 to cover, and the Nationals are -178.

Cardinals vs Nationals Over/Under

• A combined run total of 9 has been set for Cardinals-Nationals on July 10, with the over at -100 and the under at -122.

Bet on St. Louis Cardinals vs. Washington Nationals on FanDuel today!

Cardinals vs Nationals Betting Trends

• The Cardinals have come away with 21 wins in the 39 contests they have been listed as the favorites in this season.
• This year St. Louis has won eight of 12 games when listed as at least -142 on the moneyline.
• Contests with the Cardinals have gone over the total set by bookmakers in 47 of 90 chances this season.
• The Cardinals have posted a record of 49-41-0 against the spread this season.
• The Nationals have won 33 of the 69 games they were listed as the moneyline underdog this season (47.8%).
• Washington has a record of 20-27 when it has played as a moneyline underdog with odds of +120 or longer (42.6%).
• The Nationals have played in 87 games with an over/under set, and have combined with their opponents to go over the total 48 times (48-38-1).
• The Nationals have collected a 46-41-0 record against the spread this season (covering 52.9% of the time).

Cardinals Player Leaders

• Brendan Donovan has an OPS of .801, fueled by an OBP of .367 to go with a slugging percentage of .434. He has a .294 batting average, as well.
• Among qualifying hitters in MLB, he ranks 14th in batting average, 26th in on-base percentage, and 78th in slugging.
• Nolan Arenado is hitting .244 with 13 doubles, a triple, 10 home runs and 24 walks, while slugging .389 with an on-base percentage of .303.
• Among all qualifying players, he is 115th in batting average, 127th in on-base percentage and 113th in slugging percentage.
• Lars Nootbaar has collected 74 base hits, an OBP of .334 and a slugging percentage of .384 this season.
• Nootbaar has recorded a hit in two straight games. During his last five outings he is batting .278 with a double, a home run, a walk and two RBIs.
• Alec Burleson has 80 hits, which leads St. Louis hitters this season, while batting .290 with 26 extra-base hits.
• Burleson takes a two-game hitting streak into this matchup. During his last five outings he is batting .278 with a double, a home run, three walks and three RBIs.

Nationals Player Leaders

• James Wood has racked up a team-high OBP (.388) and slugging percentage (.551), while pacing the Nationals in hits (99, while batting .287).
• Including all qualified hitters in the majors, he is 25th in batting average, sixth in on-base percentage and eighth in slugging percentage.
• Wood takes a three-game hitting streak into this matchup. During his last five outings he is batting .167 with a home run, a walk and two RBIs.
• C.J. Abrams has 19 doubles, three triples, 12 home runs and 24 walks while hitting .287. He's slugging .481 with an on-base percentage of .355.
• Including all qualifying hitters, he ranks 25th in batting average, 39th in on-base percentage and 35th in slugging percentage.
• Luis Garcia is batting .266 with 19 doubles, seven home runs and 17 walks.
• Nathaniel Lowe is batting .235 with 14 doubles, two triples, 14 home runs and 33 walks.

Cardinals vs Nationals Head to Head

• 7/9/2025: 8-2 WSH (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/11/2025: 6-1 STL (Favorite: Nationals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/10/2025: 4-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/9/2025: 10-0 STL (Favorite: Nationals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 7/28/2024: 4-3 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 7/27/2024: 14-3 WSH (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 7/26/2024: 10-8 WSH (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 7/8/2024: 6-0 STL (Favorite: Nationals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/7/2024: 8-3 STL (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 7/6/2024: 14-6 WSH (Favorite: Nationals, Spread: -1.5, Total: 9, Favorite Moneyline: -132, Underdog Moneyline: +112)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!