Diamondbacks vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for July 10

Odds updated as of 11:12 a.m.

The Arizona Diamondbacks are among the MLB squads playing on Thursday, up against the San Diego Padres.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Diamondbacks vs Padres Game Info

• Arizona Diamondbacks (46-47) vs. San Diego Padres (49-43)
• Date: Thursday, July 10, 2025
• Time: 9:40 p.m. ET
• Venue: PETCO Park -- San Diego, California
• Coverage: MLB Network, SDPA, and ARID

Diamondbacks vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-120) | SD: (+102)
• Spread: ARI: -1.5 (+134) | SD: +1.5 (-162)
• Total: 8.5 -- Over: (-122) | Under: (-100)

Diamondbacks vs Padres Probable Starting Pitchers

Probable Pitchers: Eduardo Rodríguez (Diamondbacks) - 3-5, 5.78 ERA vs Randy Vasquez (Padres) - 3-4, 3.79 ERA

This contest's pitching matchup is set, as the Diamondbacks will send Eduardo Rodriguez (3-5) to the mound, while Randy Vasquez (3-4) will take the ball for the Padres. Rodriguez and his team have a record of 5-9-0 against the spread when he starts. Rodriguez's team has a record of 4-6 this season when he starts and they are the favorite on the moneyline. The Padres have a 10-7-0 ATS record in Vasquez's 17 starts that had a set spread. The Padres have been the moneyline underdog in 12 of Vasquez's starts this season, and they went 5-7 in those matchups.

Diamondbacks vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Diamondbacks win (50.3%)

Diamondbacks vs Padres Moneyline

• The Diamondbacks vs Padres moneyline has Arizona as a -120 favorite, while San Diego is a +102 underdog at home.

Diamondbacks vs Padres Spread

• The Padres are hosting the Diamondbacks, and are +1.5 on the runline. The Padres are +134 to cover the spread, and the Diamondbacks are -162.

Diamondbacks vs Padres Over/Under

• Diamondbacks versus Padres on July 10 has an over/under of 8.5 runs, with the odds on the over -122 and the under set at -100.

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Diamondbacks vs Padres Betting Trends

• The Diamondbacks have won in 30, or 50%, of the 60 contests they have been named as odds-on favorites in this year.
• Arizona has a record of 21-22 when favored by -120 or more this year.
• The Diamondbacks and their opponents have hit the over in 48 of their 90 games with a total set by oddsmakers this season.
• The Diamondbacks are 43-47-0 against the spread in their 90 games with a line set by sportsbooks this season.
• The Padres have gone 18-23 in games they were listed as the moneyline underdog (winning 43.9% of those games).
• When it has played as a moneyline underdog with odds of +102 or longer, San Diego has a record of 15-20 (42.9%).
• The Padres have played in 91 games with a set over/under, and have combined with their opponents to go over the total 38 times (38-50-3).
• The Padres have gone 47-44-0 ATS this season.

Diamondbacks Player Leaders

• Geraldo Perdomo has 90 hits this season and a team-best OBP of .368. He has a .267 batting average and a slugging percentage of .415.
• Among qualified hitters in the majors, his batting average ranks 61st, his on-base percentage ranks 25th, and he is 90th in slugging.
• Josh Naylor leads Arizona in slugging percentage (.465) thanks to 30 extra-base hits. He's batting .296 with an on-base percentage of .357.
• He is 12th in batting average, 34th in on-base percentage and 48th in slugging among qualifying hitters.
• Eugenio Suarez has 84 hits this season and has a slash line of .251/.320/.563.
• Suarez has picked up a hit in three games in a row. During his last five outings he is batting .250 with a double, a home run, a walk and three RBIs.
• Corbin Carroll has 77 hits, which is best among Arizona hitters this season, while batting .250 with 45 extra-base hits.
• Carroll brings a three-game hitting streak into this game. In his last five games he is hitting .182 with a double, a triple, a home run, a walk and two RBIs.

Padres Player Leaders

• Manny Machado has 101 hits with a .474 slugging percentage, both team-best numbers for the Padres. He's batting .287 and with an on-base percentage of .348.
• Including all qualified hitters, he ranks 25th in batting average, while his on-base percentage is 49th and he is 36th in slugging.
• Fernando Tatis Jr. paces his team with a .354 OBP. He has a batting average of .259 while slugging .440.
• Including all qualifying hitters, his batting average places him 80th, his on-base percentage ranks 41st, and he is 66th in slugging.
• Luis Arraez has a .404 slugging percentage, which paces the Padres.
• Gavin Sheets is hitting .261 with 14 doubles, a triple, 14 home runs and 26 walks.

Diamondbacks vs Padres Head to Head

• 7/9/2025: 8-2 ARI (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 7/8/2025: 1-0 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/7/2025: 6-3 ARI (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 6/15/2025: 8-2 SD (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 6/14/2025: 8-7 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 6/13/2025: 5-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/29/2024: 11-2 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 9/28/2024: 5-0 SD (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 9/27/2024: 5-3 SD (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/7/2024: 9-1 ARI (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -174, Underdog Moneyline: +146)

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