Brewers vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 5

Odds updated as of 2:12 a.m.

The Milwaukee Brewers are among the MLB squads playing on Saturday, versus the Cincinnati Reds.

All the info you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Brewers vs Reds Game Info

• Milwaukee Brewers (88-54) vs. Cincinnati Reds (67-74)
• Date: Saturday, September 5, 2026
• Time: 6:40 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: Reds.TV and Brewers.TV

Brewers vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-162) | CIN: (+136)
• Spread: MIL: -1.5 (+102) | CIN: +1.5 (-122)
• Total: 9.5 -- Over: (+102) | Under: (-124)

Brewers vs Reds Probable Starting Pitchers

Probable Pitchers: Dustin May (Brewers) - 6-9, 4.69 ERA vs Andrew Abbott (Reds) - 6-10, 4.49 ERA

This contest's pitching matchup is set, as the Brewers will send Dustin May (6-9) to the mound, while Andrew Abbott (6-10) will take the ball for the Reds. May and his team are 13-13-0 ATS this season when he starts. May's team has been victorious in 58.3% of the games he's started as the moneyline favorite with a record of 7-5. The Reds have gone 12-16-0 ATS in Abbott's 28 starts with a set spread. The Reds are 9-14 in Abbott's 23 starts this season that they were the moneyline underdog.

Brewers vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (69.6%)

Brewers vs Reds Moneyline

• The moneyline numbers for Brewers vs. Reds reveal Milwaukee as the favorite (-162) and Cincinnati as the underdog (+136) despite being the home team.

Brewers vs Reds Spread

• The Reds are +1.5 on the spread (-122 to cover), and Milwaukee is +102 to cover the runline.

Brewers vs Reds Over/Under

• Brewers versus Reds on Sept. 5 has an over/under of 9.5 runs, with the odds on the over +102 and the under set at -124.

Bet on Milwaukee Brewers vs. Cincinnati Reds on FanDuel today!

Brewers vs Reds Betting Trends

• The Brewers have come away with 69 wins in the 108 contests they have been listed as the favorites in this season.
• Milwaukee has a record of 23-12 when favored by -162 or more this year.
• The Brewers' games have gone over the total in 61 of their 141 opportunities.
• The Brewers are 74-67-0 against the spread in their 141 games with a line set by sportsbooks this season.
• The Reds have won 45 of the 93 games they were the underdog on the moneyline this season (48.4%).
• Cincinnati has gone 9-8 in games it has played as a moneyline underdog with odds of +136 or longer (52.9%).
• The Reds have combined with opponents to hit the over on the total 73 times this season for a 73-62-2 record against the over/under.
• The Reds have covered 51.8% of their games this season, going 71-66-0 against the spread.

Brewers Player Leaders

• Brice Turang has 29 doubles, three triples, 17 home runs and 74 walks while batting .252. He has an on-base percentage of .346 and a slugging percentage of .421.
• Among qualified hitters, he is 75th in batting average, his on-base percentage ranks 44th, and he is 68th in slugging.
• Jake Bauers has 113 hits and an OBP of .389, both of which lead the Brewers this season. He's batting .268 and slugging .487.
• Among qualified hitters, he is 46th in batting average, fourth in on-base percentage and 19th in slugging percentage.
• William Contreras has an OPS of .743, fueled by an OBP of .341 and a team-best slugging percentage of .402 this season.
• Jackson Chourio is batting .285 with a .344 OBP and 58 RBI for Milwaukee this season.

Reds Player Leaders

• Sal Stewart has a team-best slugging percentage (.485) while pacing the Reds in hits (143). He's batting .266 and with an on-base percentage of .336.
• Including all the qualified hitters in the majors, his batting average is 52nd, his on-base percentage ranks 62nd, and he is 22nd in slugging.
• Elly De La Cruz has a .353 on-base percentage to lead his team. He has a batting average of .273 while slugging .476.
• Including all qualifying hitters, he is 36th in batting average, 38th in on-base percentage and 29th in slugging percentage.
• JJ Bleday has 15 doubles, two triples, 22 home runs and 64 walks while batting .222.
• Tyler Stephenson is hitting .249 with 19 doubles, 14 home runs and 42 walks.

Brewers vs Reds Head to Head

• 7/2/2026: 7-2 CIN (Favorite: Brewers, Spread: -1.5, Total: 7, Favorite Moneyline: -205, Underdog Moneyline: +172)
• 7/1/2026: 4-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 9, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 6/30/2026: 7-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 9.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 6/29/2026: 5-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 6/24/2026: 6-5 MIL (Favorite: Brewers, Spread: -1.5, Total: 9.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 6/23/2026: 2-0 MIL (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 6/22/2026: 2-1 MIL (Favorite: Brewers, Spread: -1.5, Total: 9.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 9/28/2025: 4-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/27/2025: 7-4 CIN (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 9/26/2025: 3-1 CIN (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -172, Underdog Moneyline: +144)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!