Brewers vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for May 22

Odds updated as of 5:13 a.m.

MLB action on Thursday includes the Milwaukee Brewers taking on the Pittsburgh Pirates.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Brewers vs Pirates Game Info

• Milwaukee Brewers (24-26) vs. Pittsburgh Pirates (17-33)
• Date: Thursday, May 22, 2025
• Time: 6:40 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: SportsNet PT and FDSWI

Brewers vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-120) | PIT: (+102)
• Spread: MIL: -1.5 (+125) | PIT: +1.5 (-150)
• Total: 9 -- Over: (-112) | Under: (-108)

Brewers vs Pirates Probable Starting Pitchers

Probable Pitchers: TBA (Brewers) vs Mike Burrows (Pirates) - 0-0, 0.00 ERA

Burrows gets the start for the Pirates. As of this writing, there's been no pitching decision announced by the Brewers. Burrows and his team were moneyline underdogs each time he pitched a season ago.

Brewers vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Pirates win (50.5%)

Brewers vs Pirates Moneyline

• Looking at the moneyline for Brewers-Pirates, Milwaukee is the favorite at -120, and Pittsburgh is +102 playing at home.

Brewers vs Pirates Spread

• The Brewers are favored by 1.5 runs on the road against the Pirates. The Brewers are +125 to cover the spread, while the Pirates are -150.

Brewers vs Pirates Over/Under

• The over/under for the Brewers versus Pirates game on May 22 has been set at 9, with -112 odds on the over and -108 odds on the under.

Bet on Milwaukee Brewers vs. Pittsburgh Pirates on FanDuel today!

Brewers vs Pirates Betting Trends

• The Brewers have been favorites in 25 games this season and have come away with the win 17 times (68%) in those contests.
• Milwaukee has a record of 13-5 when favored by -120 or more this year.
• The Brewers' games have gone over the total in 19 of their 49 opportunities.
• The Brewers have posted a record of 26-23-0 against the spread this season.
• The Pirates have won 36.4% of the games this season they were the moneyline underdog (12-21).
• Pittsburgh is 10-19 (winning only 34.5% of its games) when playing as a moneyline underdog of +102 or longer.
• The Pirates have had an over/under set by oddsmakers 48 times, and have combined with opponents to go over the total in 17 of those games (17-28-3).
• The Pirates have covered 41.7% of their games this season, going 20-28-0 ATS.

Brewers Player Leaders

• Brice Turang leads Milwaukee in slugging percentage (.379) thanks to eight extra-base hits. He has a .288 batting average and an on-base percentage of .363.
• He ranks 30th in batting average, 39th in on-base percentage, and 112th in slugging among all qualified hitters in the majors.
• William Contreras is hitting .255 with six doubles, four home runs and 31 walks, while slugging .366 with an on-base percentage of .373.
• Among qualified hitters, his batting average places him 81st, his on-base percentage 30th, and his slugging percentage 122nd.
• Rhys Hoskins leads Milwaukee with 45 hits and an OBP of .402 this season.
• Hoskins heads into this game with five games in a row with at least one hit. During his last five outings he is hitting .412 with two doubles, two home runs, three walks and three RBIs.
• Jackson Chourio leads Milwaukee in slugging percentage (.415) thanks to 22 extra-base hits.
• Chourio takes a two-game hitting streak into this game. During his last five outings he is batting .136 with a walk and an RBI.

Pirates Player Leaders

• Oneil Cruz has racked up 32 hits with a .350 on-base percentage, leading the Pirates in both statistics. He's batting .221 and slugging .421.
• Including all qualifying hitters in the majors, he ranks 134th in batting average, 56th in on-base percentage and 77th in slugging percentage.
• Andrew McCutchen is hitting .243 with seven doubles, three home runs and 20 walks. He's slugging .357 with an on-base percentage of .344.
• Including all qualified players, he ranks 95th in batting average, 60th in on-base percentage and 132nd in slugging percentage.
• Bryan Reynolds is hitting .203 with five doubles, six home runs and 17 walks.
• Ke'Bryan Hayes is slugging .310 to lead his team.

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