Brewers vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 22

Odds updated as of 7:14 a.m.

On Friday in MLB, the Milwaukee Brewers are playing the San Francisco Giants.

We've got you covered, in terms of the most important info about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Brewers vs Giants Game Info

• Milwaukee Brewers (80-48) vs. San Francisco Giants (61-67)
• Date: Friday, August 22, 2025
• Time: 8:10 p.m. ET
• Venue: American Family Field -- Milwaukee, Wisconsin
• Coverage: FDSWI and NBCS-BA

Brewers vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-174) | SF: (+146)
• Spread: MIL: -1.5 (+122) | SF: +1.5 (-146)
• Total: 8.5 -- Over: (-108) | Under: (-112)

Brewers vs Giants Probable Starting Pitchers

Probable Pitchers: José Quintana (Brewers) - 10-4, 3.32 ERA vs Carson Whisenhunt (Giants) - 0-0, 0.00 ERA

The Brewers will give the nod to Jose Quintana (10-4, 3.32 ERA), who is eyeing win No. 11 on the season, and the Giants will turn to Carson Whisenhunt. Quintana and his team are 13-5-0 ATS this season when he starts. Quintana's team has won 62.5% of his starts when they are favored on the moneyline (5-3). Whisenhunt's team was never the underdog on the moneyline a season ago in games he pitched.

Brewers vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (51.1%)

Brewers vs Giants Moneyline

• Looking at the moneyline for Giants-Brewers, San Francisco is the underdog at +146, and Milwaukee is -174 playing at home.

Brewers vs Giants Spread

• The Brewers are hosting the Giants and are favored by 1.5 runs (+122 to cover) on the runline. San Francisco is -146 to cover.

Brewers vs Giants Over/Under

• Brewers versus Giants on Aug. 22 has an over/under of 8.5 runs, with the odds on the over -108 and the under set at -112.

Bet on Milwaukee Brewers vs. San Francisco Giants on FanDuel today!

Brewers vs Giants Betting Trends

• The Brewers have come away with 46 wins in the 67 contests they have been listed as the favorites in this season.
• This year Milwaukee has won 11 of 14 games when listed as at least -174 on the moneyline.
• The Brewers and their opponents have gone over the total this season in 61 of their 126 opportunities.
• In 126 games with a line this season, the Brewers have a mark of 74-52-0 against the spread.
• The Giants have put together a 22-27 record in games they were the underdog on the moneyline (winning 44.9% of those games).
• When playing as a moneyline underdog with odds of +146 or longer, San Francisco has gone 1-5 (16.7%).
• The Giants have combined with opponents to go over the total 58 times this season for a 58-64-6 record against the over/under.
• The Giants have collected a 54-74-0 record against the spread this season (covering 42.2% of the time).

Brewers Player Leaders

• Christian Yelich has 14 doubles, 26 home runs and 53 walks while hitting .262. He has an on-base percentage of .344 and a slugging percentage of .462.
• Among qualifying hitters in the majors, he is 62nd in batting average, 50th in on-base percentage, and 54th in slugging.
• Brice Turang leads Milwaukee in slugging percentage (.429) thanks to 38 extra-base hits. He's batting .286 with an on-base percentage of .350.
• His batting average ranks 22nd among qualified players, his on-base percentage 42nd, and his slugging percentage 80th.
• Turang brings a five-game streak with at least one hit into this one. During his last five outings he is batting .450 with a double, two home runs, a walk and six RBIs.
• William Contreras is batting .256 with a .388 slugging percentage and 61 RBI this year.
• Sal Frelick leads Milwaukee with an OBP of .364 this season while batting .300 with 37 walks and 61 runs scored.
• Frelick has safely hit in five games in a row. During his last five outings he is hitting .421 with two doubles, four walks and two RBIs.

Giants Player Leaders

• Rafael Devers has racked up a team-best OBP (.374), and paces the Giants in hits (122). He's batting .254 and slugging.
• He is 90th in batting average, 12th in on-base percentage and 46th in slugging percentage among all qualifying hitters in the majors.
• Jung Hoo Lee has 29 doubles, 10 triples, seven home runs and 40 walks while batting .262. He's slugging .415 with an on-base percentage of .325.
• Including all qualifying hitters, he ranks 62nd in batting average, 87th in on-base percentage and 91st in slugging percentage.
• Willy Adames is hitting .222 with 18 doubles, two triples, 20 home runs and 60 walks.
• Heliot Ramos paces his team with a .403 slugging percentage.

Brewers vs Giants Head to Head

• 4/24/2025: 6-5 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 4/23/2025: 4-2 SF (Favorite: Giants, Spread: -1.5, Total: 6.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/22/2025: 11-3 MIL (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/21/2025: 5-2 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/12/2024: 3-0 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 9/11/2024: 13-2 SF (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 9/10/2024: 3-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/29/2024: 6-0 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 8/28/2024: 5-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 8/27/2024: 5-4 SF (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)

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