Brewers vs Cubs Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 2

Odds updated as of 2:12 a.m.

The Wednesday schedule in MLB includes a matchup between the Milwaukee Brewers and the Chicago Cubs.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Brewers vs Cubs Game Info

• Milwaukee Brewers (86-53) vs. Chicago Cubs (78-61)
• Date: Wednesday, September 2, 2026
• Time: 7:40 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MLB Network, MARQ, and Brewers.TV

Brewers vs Cubs Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-162) | CHC: (+136)
• Spread: MIL: -1.5 (+102) | CHC: +1.5 (-122)
• Total: 8.5 -- Over: (-102) | Under: (-120)

Brewers vs Cubs Probable Starting Pitchers

Probable Pitchers: Jacob Misiorowski (Brewers) - 14-5, 1.73 ERA vs David Peterson (Cubs) - 7-7, 5.11 ERA

This contest's pitching matchup is set, as the Brewers will send Jacob Misiorowski (14-5) to the mound, while David Peterson (7-7) will get the nod for the Cubs. Misiorowski and his team are 15-10-0 ATS this season when he starts. When Misiorowski starts a game and his team is the favorite on the moneyline, they have a record of 16-6. The Cubs have a 7-10-0 ATS record in Peterson's 17 starts with a set spread. The Cubs have been the underdog on the moneyline in seven of Peterson's starts this season, and they went 2-5 in those games.

Brewers vs Cubs Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (50.4%)

Brewers vs Cubs Moneyline

• Looking at the moneyline for Brewers-Cubs, Milwaukee is the favorite at -162, and Chicago is +136 playing at home.

Brewers vs Cubs Spread

• The Brewers are at the Cubs and are favored by 1.5 runs (+102 to cover) on the runline. Chicago is -122 to cover.

Brewers vs Cubs Over/Under

• The over/under for Brewers-Cubs on Sept. 2 is 8.5. The over is -102, and the under is -120.

Bet on Milwaukee Brewers vs. Chicago Cubs on FanDuel today!

Brewers vs Cubs Betting Trends

• The Brewers have been chosen as favorites in 106 games this year and have walked away with the win 68 times (64.2%) in those games.
• This season Milwaukee has been victorious 23 times in 35 chances when named as a favorite of at least -162 on the moneyline.
• The Brewers and their opponents have gone over the total this season in 60 of their 139 opportunities.
• The Brewers have posted a record of 73-66-0 against the spread this season.
• The Cubs have put together a 22-18 record in games they were listed as the moneyline underdog (winning 55% of those games).
• Chicago has a 3-2 record (winning 60% of its games) when playing as a moneyline underdog of +136 or longer.
• The Cubs have played in 134 games with a set over/under, and have combined with opponents to go over the total 75 times (75-59-0).
• The Cubs have gone 65-69-0 against the spread this season.

Brewers Player Leaders

• Brice Turang has 29 doubles, three triples, 17 home runs and 74 walks while hitting .256. He has an on-base percentage of .351 and a slugging percentage of .427.
• Among qualified hitters in the majors, his batting average ranks 65th, his on-base percentage ranks 41st, and he is 61st in slugging.
• Jake Bauers leads the Brewers in OBP (.392) and total hits (113) this season. He's batting .273 while slugging .495.
• Among qualifying batters, his batting average ranks him 38th, his on-base percentage fourth, and his slugging percentage 18th.
• William Contreras has hit 13 homers with a team-high .405 SLG this season.
• Contreras takes a four-game hitting streak into this game. In his last five games he is batting .389 with three doubles, a home run, three walks and six RBIs.
• Jackson Chourio is batting .282 with a .343 OBP and 57 RBI for Milwaukee this season.
• Chourio brings a six-game hitting streak into this game. In his last 10 games he is batting .302 with a double, three home runs, three walks and seven RBIs.

Cubs Player Leaders

• Pete Crow-Armstrong has accumulated a team-high OBP (.374) and slugging percentage (.569), and paces the Cubs in hits (150, while batting .280).
• Including all the qualified players in MLB, he ranks 25th in batting average, 13th in on-base percentage and second in slugging percentage.
• Alex Bregman has 27 doubles, a triple, 23 home runs and 66 walks while hitting .258. He's slugging .438 with an on-base percentage of .345.
• Including all qualifying players, he is 62nd in batting average, 51st in on-base percentage and 55th in slugging percentage.
• Seiya Suzuki has 28 doubles, 24 home runs and 67 walks while batting .276.
• Nico Hoerner is hitting .263 with 27 doubles, a triple, eight home runs and 41 walks.

Brewers vs Cubs Head to Head

• 9/1/2026: 9-4 MIL (Favorite: Cubs, Spread: -1.5, Total: 10, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/31/2026: 17-3 CHC (Favorite: Brewers, Spread: -1.5, Total: 9.5, Favorite Moneyline: -106, Underdog Moneyline: -102)
• 6/28/2026: 4-3 CHC (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 6/27/2026: 8-2 CHC (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 6/26/2026: 6-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 7, Favorite Moneyline: -250, Underdog Moneyline: +205)
• 5/20/2026: 5-0 MIL (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -118, Underdog Moneyline: +100)
• 5/19/2026: 5-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/18/2026: 9-3 MIL (Favorite: Cubs, Spread: -1.5, Total: 10.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 10/11/2025: 3-1 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 10/9/2025: 6-0 CHC (Favorite: Brewers, Spread: -1.5, Total: 7, Favorite Moneyline: -118, Underdog Moneyline: -100)

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