Braves vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for April 22

Odds updated as of 4:16 a.m.

The Atlanta Braves are among the MLB teams busy on Tuesday, versus the St. Louis Cardinals.

We've got you covered, in terms of the vital info about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Braves vs Cardinals Game Info

• Atlanta Braves (9-13) vs. St. Louis Cardinals (9-14)
• Date: Tuesday, April 22, 2025
• Time: 7:15 p.m. ET
• Venue: Truist Park -- Atlanta, Georgia
• Coverage: FDSSO and FDSMW

Braves vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ATL: (-136) | STL: (+116)
• Spread: ATL: -1.5 (+146) | STL: +1.5 (-178)
• Total: 8.5 -- Over: (-110) | Under: (-110)

Braves vs Cardinals Probable Starting Pitchers

Probable Pitchers: Spencer Strider (Braves) - 0-1, 3.60 ERA vs Andre Pallante (Cardinals) - 2-1, 3.22 ERA

The Braves will call on Spencer Strider (0-1) against the Cardinals and Andre Pallante (2-1). Strider and his team failed to cover the spread in his only opportunity this season as a starter. Strider's team lost his only start as a favorite this season. The Cardinals have gone 2-2-0 against the spread when Pallante starts. The Cardinals have been the moneyline underdog in four of Pallante's starts this season, and they went 2-2 in those matchups.

Braves vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (51.7%)

Braves vs Cardinals Moneyline

• St. Louis is a +116 underdog on the moneyline, while Atlanta is a -136 favorite at home.

Braves vs Cardinals Spread

• The Braves are 1.5-run home favorites on the runline against the Cardinals. The Braves are +146 to cover, and the Cardinals are -178.

Braves vs Cardinals Over/Under

• A combined run total of 8.5 has been set for Braves-Cardinals on April 22, with the over at -110 and the under at -110.

Bet on Atlanta Braves vs. St. Louis Cardinals on FanDuel today!

Braves vs Cardinals Betting Trends

• The Braves have been favorites in 15 games this season and have come away with the win eight times (53.3%) in those contests.
• This season Atlanta has come away with a win four times in eight chances when named as a favorite of at least -136 on the moneyline.
• The Braves and their opponents have gone over in 10 of their 22 games with a total set by sportsbooks this season.
• The Braves have posted a record of 9-13-0 against the spread this season.
• The Cardinals have won 41.2% of the games this season they were the underdog on the moneyline (7-10).
• St. Louis has gone 2-5 when it has played as a moneyline underdog with odds of +116 or longer (28.6%).
• The Cardinals have played in 23 games with an over/under set, and have combined with their opponents to go over the total 13 times (13-9-1).
• The Cardinals have put together an 11-12-0 record ATS this season (covering 47.8% of the time).

Braves Player Leaders

• Marcell Ozuna leads Atlanta in OBP (.481) and total hits (20) this season. He's batting .323 batting average while slugging .548.
• Among qualifying hitters in the majors, he is 15th in batting average, second in on-base percentage, and 18th in slugging.
• Ozuna has recorded a base hit in three games in a row. During his last five outings he is hitting .313 with a home run, three walks and an RBI.
• Ozhaino Jurdy Jiandro Albies has three doubles, four home runs and nine walks. He's batting .235 and slugging .412 with an on-base percentage of .309.
• He is 90th in batting average, 108th in on-base percentage and 87th in slugging among qualified hitters.
• Matt Olson has collected 18 base hits, an OBP of .376 and a slugging percentage of .408 this season.
• Olson brings a six-game hitting streak into this game. During his last 10 outings he is batting .294 with a double, two home runs, six walks and eight RBI.
• Austin Riley leads Atlanta with a slugging percentage of .522, fueled by 10 extra-base hits.
• Riley heads into this game on a three-game hitting streak. During his last five outings he is batting .200 with a home run, a walk and three RBI.

Cardinals Player Leaders

• Brendan Donovan has put up a team-best OBP (.392) and slugging percentage (.533), while leading the Cardinals in hits (32, while batting .356).
• Including all the qualified hitters in MLB, his batting average is third, his on-base percentage ranks 23rd, and he is 23rd in slugging.
• Nolan James Arenado is batting .282 with seven doubles, two home runs and 12 walks. He's slugging .449 with an on-base percentage of .385.
• Including all qualified hitters, his batting average puts him 52nd, his on-base percentage is 29th, and he is 60th in slugging.
• Lars Nootbaar has three doubles, three home runs and 17 walks while hitting .238.
• Victor Scott II is batting .264 with three doubles, a triple, a home run and seven walks.

Braves vs Cardinals Head to Head

• 4/21/2025: 7-6 ATL (Favorite: Braves, Spread: -1.5, Total: 8.5, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 7/21/2024: 6-2 STL (Favorite: Braves, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/20/2024: 9-5 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/20/2024: 3-2 ATL (Favorite: Braves, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 6/26/2024: 4-1 STL (Favorite: Braves, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/24/2024: 4-3 STL (Favorite: Braves, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/7/2023: 8-5 ATL (Favorite: Braves, Spread: -1.5, Total: 10.5, Favorite Moneyline: -335, Underdog Moneyline: +270)
• 9/6/2023: 11-6 STL (Favorite: Braves, Spread: -1.5, Total: 9, Favorite Moneyline: -330, Underdog Moneyline: +265)
• 9/5/2023: 10-6 STL (Favorite: Braves, Spread: -1.5, Total: 10.5, Favorite Moneyline: -205, Underdog Moneyline: +172)
• 4/5/2023: 5-2 ATL (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)

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