Athletics vs Angels Prediction, Odds, Moneyline, Spread & Over/Under for May 22

Odds updated as of 4:11 a.m.

The MLB schedule on Thursday includes the Athletics facing the Los Angeles Angels.

We've got you covered, in terms of the most important info regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Athletics vs Angels Game Info

• Athletics (22-28) vs. Los Angeles Angels (23-25)
• Date: Thursday, May 22, 2025
• Time: 3:35 p.m. ET
• Venue: Sutter Health Park -- West Sacramento, California
• Coverage: NBCS-CA and FDSW

Athletics vs Angels Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: OAK: (-156) | LAA: (+132)
• Spread: OAK: -1.5 (+122) | LAA: +1.5 (-146)
• Total: 10 -- Over: (-105) | Under: (-115)

Athletics vs Angels Probable Starting Pitchers

Probable Pitchers: Luis Severino (Athletics) - 1-4, 4.22 ERA vs Tyler Anderson (Angels) - 2-1, 3.04 ERA

The Athletics will give the ball to Luis Severino (1-4, 4.22 ERA), who is eyeing win No. 2 on the season, and the Angels will counter with Tyler Anderson (2-1, 3.04 ERA). Severino's team is 5-5-0 against the spread this season in his starts. Severino's team won his only start as a favorite this season. The Angels have a 6-3-0 ATS record in Anderson's nine starts with a set spread. The Angels have been the underdog on the moneyline in eight of Anderson's starts this season, and they went 6-2 in those matchups.

Athletics vs Angels Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Athletics win (55.4%)

Athletics vs Angels Moneyline

• The Athletics vs Angels moneyline has the Athletics as a -156 favorite, while the Angels are a +132 underdog on the road.

Athletics vs Angels Spread

• The Athletics are 1.5-run favorites on the runline against the Angels. The Athletics are +122 to cover, while the Angels are -146 to cover.

Athletics vs Angels Over/Under

• The over/under for the Athletics versus Angels contest on May 22 has been set at 10, with -105 odds on the over and -115 odds on the under.

Bet on Athletics vs. Los Angeles Angels on FanDuel today!

Athletics vs Angels Betting Trends

• The Athletics have been victorious in nine, or 52.9%, of the 17 contests they have been chosen as favorites in this season.
• This year, the Athletics have won four of seven games when listed as at least -156 or better on the moneyline.
• The Athletics and their opponents have hit the over in 27 of their 50 games with a total this season.
• The Athletics have posted a record of 24-26-0 against the spread this season.
• The Angels have a 19-21 record in games they were the underdog on the moneyline (winning 47.5% of those games).
• The Angels have gone 9-9 when they have played as a moneyline underdog with odds of +132 or longer (50%).
• The Angels have combined with their opponents to hit the over on the total 27 times this season for a 27-20-1 record against the over/under.
• The Angels have covered 45.8% of their games this season, going 22-26-0 ATS.

Athletics Player Leaders

• Jacob Wilson has an OPS of .859, fueled by an OBP of .381 to go with a slugging percentage of .478. He has a .341 batting average, as well.
• He ranks third in batting average, 19th in on-base percentage, and 42nd in slugging among all qualifying hitters in MLB.
• Tyler Soderstrom leads Sacramento in total hits (54) this season while batting .280 with 20 extra-base hits. He's slugging .487 with an on-base percentage of .340.
• Among qualified hitters, his batting average places him 44th, his on-base percentage 65th, and his slugging percentage 33rd.
• Soderstrom heads into this matchup looking to extend his three-game hit streak. During his last five outings he is hitting .286 with two doubles and a walk.
• Shea Langeliers has collected 41 base hits, an OBP of .317 and a slugging percentage of .451 this season.
• Brent Rooker has 10 home runs, 23 RBI and a batting average of .235 this season.

Angels Player Leaders

• Taylor Ward has 10 doubles, a triple, 13 home runs and 12 walks while hitting .214. He's slugging .487 with an on-base percentage of .259.
• Including all the qualified hitters in the majors, his batting average ranks 141st, his on-base percentage is 155th, and he is 33rd in slugging.
• Ward takes a seven-game hitting streak into this matchup. In his last 10 outings he is hitting .349 with five doubles, a triple, five home runs, three walks and 13 RBIs.
• Nolan Schanuel has a .366 OBP while slugging .403. Both pace his team. He has a batting average of .277.
• His batting average ranks 50th among all qualified players, his on-base percentage ranks 36th, and he is 94th in slugging.
• Zach Neto has nine doubles, eight home runs and seven walks while batting .283.
• Logan O'Hoppe has collected 40 hits to lead his team.

Athletics vs Angels Head to Head

• 5/21/2025: 10-5 LAA (Favorite: Athletics, Spread: -1.5, Total: 10.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/20/2025: 7-5 LAA (Favorite: Athletics, Spread: -1.5, Total: 10.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 5/19/2025: 4-3 LAA (Favorite: Athletics, Spread: -1.5, Total: 9.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 7/28/2024: 8-6 LAA (Favorite: Angels, Spread: -1.5, Total: 9.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/27/2024: 3-1 OAK (Favorite: Angels, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/26/2024: 5-4 OAK (Favorite: Angels, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/25/2024: 6-5 OAK (Favorite: Athletics, Spread: -1.5, Total: 9.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 7/21/2024: 8-5 LAA (Favorite: Athletics, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/20/2024: 8-2 OAK (Favorite: Athletics, Spread: -1.5, Total: 9, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 7/19/2024: 13-3 OAK (Favorite: Athletics, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)

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