Astros vs Athletics Prediction, Odds, Moneyline, Spread & Over/Under for June 5

Odds updated as of 2:12 a.m.

The Houston Astros are among the MLB squads playing on Friday, versus the Athletics.

All the information you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Astros vs Athletics Game Info

• Houston Astros (28-36) vs. Athletics (30-32)
• Date: Friday, June 5, 2026
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and NBCS-CA

Astros vs Athletics Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-108) | OAK: (-108)
• Spread: HOU: +1.5 (-178) | OAK: -1.5 (+146)
• Total: 9 -- Over: (-105) | Under: (-115)

Astros vs Athletics Probable Starting Pitchers

Probable Pitchers: Peter Lambert (Astros) - 4-4, 3.77 ERA vs Jack Perkins (Athletics) - 2-2, 5.46 ERA

The probable pitchers are Peter Lambert (4-4) for the Astros and Jack Perkins (2-2) for the Athletics. Lambert and his team have a record of 4-4-0 against the spread when he starts. Lambert's team lost his only start as a favorite this season. Last season when Perkins pitched his team finished 3-1-0 against the spread. Perkins and his team never lost a game he pitched when they were the moneyline underdog a season ago (in two chances).

Astros vs Athletics Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Athletics win (52.2%)

Astros vs Athletics Moneyline

• The Astros vs Athletics moneyline has the Astros as a -108 favorite, while the Athletics are a -108 underdog on the road.

Astros vs Athletics Spread

Astros vs Athletics Over/Under

• Astros versus Athletics on June 5 has an over/under of 9 runs, with the odds on the over -105 and the under set at -115.

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Astros vs Athletics Betting Trends

• The Astros have won in five, or 29.4%, of the 17 contests they have been named as odds-on favorites in this year.
• This year, the Astros have won six of 19 games when listed as at least -108 or better on the moneyline.
• The Astros and their opponents have hit the over in 35 of their 64 games with a total this season.
• In 64 games with a line this season, the Astros have a mark of 29-35-0 against the spread.
• The Athletics are 22-20 in games they were listed as the moneyline underdog (winning 52.4% of those games).
• When playing as a moneyline underdog with odds of -108 or longer, the Athletics have gone 22-20 (52.4%).
• The Athletics have played in 62 games with an over/under set, and have combined with their opponents to go over the total 31 times (31-30-1).
• The Athletics have put together a 31-31-0 record against the spread this season (covering 50% of the time).

Astros Player Leaders

• Yordan Alvarez leads Houston with 72 hits and an OBP of .428, plus a team-best slugging percentage of .649. He's batting .316.
• Among all qualified hitters in baseball, he ranks sixth in batting average, second in on-base percentage, and first in slugging.
• Alvarez will look for his fourth straight game with a hit in this contest. During his last five outings he is batting .474 with two doubles, a home run, three walks and five RBIs.
• Christian Walker is hitting .247 with 10 doubles, 16 home runs and 21 walks. He's slugging .494 with an on-base percentage of .318.
• He is 89th in batting average, 102nd in on-base percentage and 30th in slugging among qualified hitters.
• Walker has picked up a hit in three games in a row. In his last five games he is hitting .182 with a home run and five RBIs.
• Isaac Paredes has collected 50 base hits, an OBP of .331 and a slugging percentage of .400 this season.
• Paredes heads into this matchup with two games in a row with at least one hit. In his last five games he is hitting .278 with two doubles, two home runs, three walks and six RBIs.
• Cam Smith has six home runs, 24 RBI and a batting average of .216 this season.

Athletics Player Leaders

• Nick Kurtz has racked up a team-high .437 on-base percentage. He's batting .284 and slugging .500.
• Including all the qualifying hitters in the big leagues, his batting average puts him 32nd, his on-base percentage ranks first, and he is 29th in slugging.
• Shea Langeliers leads his team with 66 hits and has a club-high .557 slugging percentage. He has a batting average of .289 with an on-base percentage of .358.
• Including all qualifying hitters, his batting average places him 23rd, his on-base percentage ranks 41st, and he is sixth in slugging.
• Tyler Soderstrom is batting .231 with 17 doubles, two triples, eight home runs and 27 walks.
• Carlos Cortes has nine doubles, a triple, five home runs and 19 walks while hitting .322.

Astros vs Athletics Head to Head

• 4/5/2026: 12-10 OAK (Favorite: Astros, Spread: -1.5, Total: 10, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 4/4/2026: 11-0 HOU (Favorite: Athletics, Spread: -1.5, Total: 9.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 4/3/2026: 11-4 OAK (Favorite: Athletics, Spread: -1.5, Total: 10, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 9/25/2025: 11-5 HOU (Favorite: Astros, Spread: -1.5, Total: 9.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/24/2025: 6-0 OAK (Favorite: Astros, Spread: -1.5, Total: 9.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 9/23/2025: 5-1 OAK (Favorite: Athletics, Spread: -1.5, Total: 10, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 7/27/2025: 7-1 OAK (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/26/2025: 5-1 OAK (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 7/25/2025: 15-3 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 7/24/2025: 5-2 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)

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