Phillies vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for June 5

Odds updated as of 1:12 a.m.

The Philadelphia Phillies will take on the Chicago White Sox in MLB action on Friday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info regarding this game.

Phillies vs White Sox Game Info

• Philadelphia Phillies (33-29) vs. Chicago White Sox (33-29)
• Date: Friday, June 5, 2026
• Time: 6:40 p.m. ET
• Venue: Citizens Bank Park -- Philadelphia, Pennsylvania
• Coverage: NBCS-PH and CHSN

Phillies vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-188) | CHW: (+158)
• Spread: PHI: -1.5 (+108) | CHW: +1.5 (-130)
• Total: 8.5 -- Over: (-105) | Under: (-115)

Phillies vs White Sox Probable Starting Pitchers

Probable Pitchers: Jesús Luzardo (Phillies) - 4-4, 4.30 ERA vs Anthony Kay (White Sox) - 5-1, 3.77 ERA

The Phillies will give the nod to Jesus Luzardo (4-4) versus the White Sox and Anthony Kay (5-1). When Luzardo starts, his team is 5-7-0 against the spread this season. Luzardo's team has been victorious in 44.4% of the games he's started as the moneyline favorite with a record of 4-5. The White Sox are 7-2-0 against the spread when Kay starts. The White Sox have been the moneyline underdog in nine of Kay's starts this season, and they went 6-3 in those games.

Phillies vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Phillies win (65.5%)

Phillies vs White Sox Moneyline

• The Phillies vs White Sox moneyline has Philadelphia as a -188 favorite, while Chicago is a +158 underdog on the road.

Phillies vs White Sox Spread

• The White Sox are at the Phillies, and are +1.5 on the runline. The White Sox are +108 to cover the spread, and the Phillies are -130.

Phillies vs White Sox Over/Under

• Phillies versus White Sox, on June 5, has an over/under of 8.5, with the over being -105 and the under -115.

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Phillies vs White Sox Betting Trends

• The Phillies have been victorious in 25, or 59.5%, of the 42 contests they have been chosen as favorites in this season.
• Philadelphia has a record of 8-1 in contests when bookmakers favor them by -188 or more on the moneyline.
• Contests with the Phillies have gone over the total set by bookmakers in 26 of 61 chances this season.
• The Phillies have an against the spread record of 19-42-0 in 61 games with a line this season.
• The White Sox have won 24 of the 49 games they were the underdog on the moneyline this season (49%).
• Chicago is 1-2 (winning just 33.3% of its games) when playing as a moneyline underdog of +158 or longer.
• The White Sox have played in 60 games with an over/under set, and have combined with opponents to go over the total 34 times (34-25-1).
• The White Sox have gone 35-25-0 against the spread this season.

Phillies Player Leaders

• Bryce Harper has 56 hits this season and a team-best OBP of .363. He has a .259 batting average and a slugging percentage of .509.
• Among qualifying batters in the majors, his batting average ranks 64th, his on-base percentage ranks 36th, and he is 23rd in slugging.
• Kyle Schwarber leads Philadelphia with 52 hits. He is batting .233 this season and has 33 extra-base hits. He's also slugging .592 with an on-base percentage of .352.
• He ranks 118th in batting average, 51st in on-base percentage and third in slugging in the major leagues.
• Schwarber has picked up at least one hit in two straight games. In his last five games he is hitting .176 with a home run, five walks and an RBI.
• Brandon Marsh leads the Phillies with an OPS of .840. He has a slash line of .333/.363/.478 this season.
• Marsh brings a three-game hitting streak into this matchup. In his last five games he is hitting .412 with a walk and an RBI.
• Trea Turner has seven home runs, 20 RBI and a batting average of .228 this season.
• Turner brings a five-game hitting streak into this game. During his last five outings he is hitting .300 with an RBI.

White Sox Player Leaders

• Miguel Vargas is hitting .242 with 10 doubles, a triple, 15 home runs and 40 walks. He's slugging .502 with an on-base percentage of .368.
• He ranks 101st in batting average, 31st in on-base percentage and 26th in slugging percentage among all qualifying hitters in MLB.
• Vargas heads into this game on a three-game hitting streak. During his last five outings he is hitting .316 with a double, two home runs, three walks and seven RBIs.
• Chase Meidroth's .397 slugging percentage paces his team. He has a batting average of .272 with an on-base percentage of .345.
• He is currently 50th in batting average, 64th in on-base percentage and 102nd in slugging percentage among all qualified hitters.
• Colson Montgomery is hitting .222 with 11 doubles, 15 home runs and 22 walks.
• Sam Antonacci is hitting .291 with eight doubles, two triples, a home run and 11 walks.

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