Angels vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for May 4

Odds updated as of 6:13 a.m.

MLB action on Monday includes the Los Angeles Angels taking on the Chicago White Sox.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Angels vs White Sox Game Info

• Los Angeles Angels (13-22) vs. Chicago White Sox (16-18)
• Date: Monday, May 4, 2026
• Time: 9:38 p.m. ET
• Venue: Angel Stadium -- Anaheim, California
• Coverage: ABTV and CHSN

Angels vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAA: (-162) | CHW: (+136)
• Spread: LAA: -1.5 (+128) | CHW: +1.5 (-154)
• Total: 7.5 -- Over: (-122) | Under: (+100)

Angels vs White Sox Probable Starting Pitchers

Probable Pitchers: José Soriano (Angels) - 5-1, 0.84 ERA vs Davis Martin (White Sox) - 4-1, 1.95 ERA

The probable pitchers are Jose Soriano (5-1) for the Angels and Davis Martin (4-1) for the White Sox. Soriano and his team are 6-1-0 ATS this season when he starts. Soriano's team is 2-1 this season when he starts and they are the moneyline favorite. The White Sox have gone 5-1-0 against the spread when Martin starts. The White Sox are 5-1 in Martin's six starts this season that they were the moneyline underdog.

Angels vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Angels win (55.6%)

Angels vs White Sox Moneyline

• The moneyline numbers for Angels vs. White Sox reveal Los Angeles as the favorite (-162) and Chicago as the underdog (+136) on the road.

Angels vs White Sox Spread

• The White Sox are +1.5 on the spread (-154 to cover), and Los Angeles is +128 to cover the runline.

Angels vs White Sox Over/Under

• Angels versus White Sox on May 4 has an over/under of 7.5 runs, with the odds on the over -122 and the under set at +100.

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Angels vs White Sox Betting Trends

• The Angels have won in two of the five contests they have been named as odds-on favorites in this year.
• Los Angeles has not played a game this season with better moneyline odds than -162.
• The Angels' games have gone over the total in 16 of their 34 opportunities.
• The Angels have an against the spread record of 17-17-0 in 34 games with a line this season.
• The White Sox have won 13 of the 29 games they were the underdog on the moneyline this season (44.8%).
• In games it has played as a moneyline underdog with odds of +136 or longer, Chicago has gone 4-5 (44.4%).
• The White Sox have played in 32 games with an over/under set, and have combined with opponents to go over the total 17 times (17-15-0).
• The White Sox have put together an 18-14-0 record ATS this season.

Angels Player Leaders

• Mike Trout has 31 hits and an OBP of .433, both of which are best among Los Angeles hitters this season. He has a .258 batting average and a slugging percentage of .550.
• Among qualifying hitters in MLB, he is 73rd in batting average, second in on-base percentage, and 14th in slugging.
• Trout hopes to build on an eight-game hitting streak in this matchup. In his last 10 games he is batting .314 with a double, three home runs, 11 walks and five RBIs.
• Jorge Soler has five doubles, seven home runs and 15 walks. He's batting .239 and slugging .469 with an on-base percentage of .336.
• His batting average ranks 105th among qualified players, his on-base percentage 81st, and his slugging percentage 46th.
• Soler brings a nine-game streak with at least one hit into this one. During his last 10 outings he is batting .270 with two doubles, two home runs, five walks and seven RBIs.
• Zach Neto has 30 hits this season and has a slash line of .216/.331/.381.
• Nolan Schanuel has three home runs, 19 RBI and a batting average of .248 this season.
• Schanuel enters this game on a three-game hitting streak. In his last five games he is batting .353 with a double.

White Sox Player Leaders

• Miguel Vargas has four doubles, a triple, six home runs and 24 walks while batting .220. He's slugging .424 with an on-base percentage of .359.
• He ranks 133rd in batting average, 52nd in on-base percentage and 70th in slugging percentage among all qualifying hitters in MLB.
• Vargas hopes to build on a six-game hitting streak in this matchup. In his last 10 games he is hitting .286 with a double, a home run, eight walks and five RBIs.
• Munetaka Murakami has racked up 27 hits with a .362 on-base percentage to lead his team in both. He has a batting average of .223 while slugging .545.
• Including all qualifying players, his batting average places him 129th, his on-base percentage is 47th, and he is 16th in slugging.
• Colson Montgomery has five doubles, nine home runs and 14 walks while batting .227.
• Chase Meidroth is slugging .350 to pace his team.

Angels vs White Sox Head to Head

• 4/29/2026: 3-2 CHW (Favorite: Angels, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: +100)
• 4/28/2026: 5-2 CHW (Favorite: Angels, Spread: -1.5, Total: 7.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 8/3/2025: 8-5 LAA (Favorite: Angels, Spread: -1.5, Total: 9.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 8/2/2025: 1-0 CHW (Favorite: Angels, Spread: -1.5, Total: 9, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 8/1/2025: 6-3 CHW (Favorite: Angels, Spread: -1.5, Total: 9, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 3/30/2025: 3-2 LAA (Favorite: Angels, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 3/29/2025: 1-0 LAA (Favorite: Angels, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 3/27/2025: 8-1 CHW (Favorite: Angels, Spread: -1.5, Total: 7.5, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 9/26/2024: 7-0 CHW (Favorite: Angels, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 9/25/2024: 4-3 CHW (Favorite: Angels, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)

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