Yankees vs Rays Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 23

Odds updated as of 1:11 a.m.

On Wednesday in MLB, the New York Yankees are up against the Tampa Bay Rays.

We've got you covered, in terms of the vital info about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Yankees vs Rays Game Info

• New York Yankees (90-67) vs. Tampa Bay Rays (96-61)
• Date: Wednesday, September 23, 2026
• Time: 7:05 p.m. ET
• Venue: Yankee Stadium -- The Bronx, New York
• Coverage: Amazon Prime Video and Rays.TV

Yankees vs Rays Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-158) | TB: (+134)
• Spread: NYY: -1.5 (+152) | TB: +1.5 (-184)
• Total: 7.5 -- Over: (+114) | Under: (-140)

Yankees vs Rays Probable Starting Pitchers

Probable Pitchers: Gerrit Cole (Yankees) - 9-9, 3.63 ERA vs Ian Seymour (Rays) - 9-7, 4.38 ERA

The Yankees will give the nod to Gerrit Cole (9-9, 3.63 ERA), who is eyeing win No. 10 on the season, and the Rays will counter with Ian Seymour (9-7, 4.38 ERA). When Cole starts, his team is 8-13-0 against the spread this season. Cole's team has a record of 8-8 this season when he starts and they are the favorite on the moneyline. The Rays have a 7-7-0 record against the spread in Seymour's starts. The Rays were the underdog on the moneyline for two Seymour starts this season -- they won both.

Yankees vs Rays Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Rays win (53.2%)

Yankees vs Rays Moneyline

• New York is the favorite, -158 on the moneyline, while Tampa Bay is a +134 underdog on the road.

Yankees vs Rays Spread

• The Rays are at +1.5 on the runline against the Yankees. The Rays are -184 to cover the spread, and the Yankees are +152.

Yankees vs Rays Over/Under

• An over/under of 7.5 has been set for Yankees-Rays on Sept. 23, with the over being +114 and the under -140.

Bet on New York Yankees vs. Tampa Bay Rays on FanDuel today!

Yankees vs Rays Betting Trends

• The Yankees have won in 72, or 59.5%, of the 121 contests they have been named as odds-on favorites in this year.
• New York has a record of 31-15 when favored by -158 or more this year.
• The Yankees and their opponents have gone over the total this season in 71 of their 152 opportunities.
• The Yankees are 78-74-0 against the spread in their 152 games with a line set by sportsbooks this season.
• The Rays have won 54.3% of the games this season they were the underdog on the moneyline (25-21).
• In games it has played as a moneyline underdog with odds of +134 or longer, Tampa Bay has a 3-1 record (winning 75% of its games).
• The Rays have played in 155 games with a set over/under, and have combined with opponents to go over the total 72 times (72-81-2).
• The Rays have put together an 83-72-0 record against the spread this season.

Yankees Player Leaders

• Ben Rice leads New York with 145 hits and an OBP of .359, plus a team-best slugging percentage of .525. He's batting .260.
• Among qualifying hitters in MLB, he ranks 64th in batting average, 30th in on-base percentage, and third in slugging.
• Luis Garcia has 141 hits, which is tops among New York batters this season. He's batting .277 with 61 extra-base hits. He's also slugging .525 with an on-base percentage of .307.
• Among qualifiers, he is 27th in batting average, 107th in on-base percentage and third in slugging percentage.
• Cody Bellinger is batting .268 with a .436 slugging percentage and 73 RBI this year.
• Jazz Chisholm has been key for New York with 108 hits, an OBP of .313 plus a slugging percentage of .403.
• Chisholm heads into this matchup on a three-game hitting streak. During his last five outings he is hitting .250 with three walks.

Rays Player Leaders

• Junior Caminero has collected 165 hits, a team-high for the Rays. He's batting .275 and slugging .525 with an on-base percentage of .361.
• Including all qualified hitters in the big leagues, he is 35th in batting average, 28th in on-base percentage and third in slugging percentage.
• Yandy Diaz paces his team with a .445 slugging percentage. He has a batting average of .291 with an on-base percentage of .357.
• Including all qualified hitters, his batting average puts him 11th, his on-base percentage ranks 37th, and he is 49th in slugging.
• Liam Hicks has put up an on-base percentage of .369, a team-high for the Rays.
• Chandler Simpson is hitting .309 with 16 doubles, six triples and 26 walks.

Yankees vs Rays Head to Head

• 9/22/2026: 6-1 TB (Favorite: Yankees, Spread: -1.5, Total: 6.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/22/2026: 2-0 NYY (Favorite: Yankees, Spread: -1.5, Total: 6.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 7/9/2026: 12-4 NYY (Favorite: Rays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 7/8/2026: 3-0 TB (Favorite: Rays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: +100)
• 7/7/2026: 6-4 TB (Favorite: Rays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 7/6/2026: 5-1 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/24/2026: 2-0 NYY (Favorite: Yankees, Spread: -1.5, Total: 7, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 5/22/2026: 4-2 TB (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 4/12/2026: 5-4 TB (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 4/11/2026: 5-4 TB (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -172, Underdog Moneyline: +144)

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