Yankees vs Diamondbacks Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 18

Odds updated as of 5:12 a.m.

The MLB's Friday slate includes the New York Yankees facing the Arizona Diamondbacks.

We've got you covered, in terms of the most important info regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Yankees vs Diamondbacks Game Info

• New York Yankees (88-64) vs. Arizona Diamondbacks (80-73)
• Date: Friday, September 18, 2026
• Time: 9:40 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: Dbacks.TV and YES

Yankees vs Diamondbacks Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-126) | ARI: (+108)
• Spread: NYY: -1.5 (+134) | ARI: +1.5 (-162)
• Total: 8.5 -- Over: (+100) | Under: (-122)

Yankees vs Diamondbacks Probable Starting Pitchers

Probable Pitchers: Gerrit Cole (Yankees) - 8-9, 3.67 ERA vs Eduardo Rodríguez (Diamondbacks) - 15-6, 2.62 ERA

This contest's pitching matchup is set, as the Yankees will send Gerrit Cole (8-9) to the mound, while Eduardo Rodriguez (15-6) will answer the bell for the Diamondbacks. Cole and his team are 7-13-0 ATS this season when he starts. Cole's team has a record of 8-8 this season when he starts and they are the favorite on the moneyline. The Diamondbacks have gone 18-12-0 ATS in Rodríguez's 30 starts that had a set spread. The Diamondbacks have been the moneyline underdog in 17 of Rodríguez's starts this season, and they went 13-4 in those games.

Yankees vs Diamondbacks Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Yankees win (56.3%)

Yankees vs Diamondbacks Moneyline

• The Yankees vs Diamondbacks moneyline has New York as a -126 favorite, while Arizona is a +108 underdog at home.

Yankees vs Diamondbacks Spread

• The Diamondbacks are +1.5 on the spread (-162 to cover), and New York is +134 to cover the runline.

Yankees vs Diamondbacks Over/Under

• Yankees versus Diamondbacks on Sept. 18 has an over/under of 8.5 runs, with the odds on the over +100 and the under set at -122.

Bet on New York Yankees vs. Arizona Diamondbacks on FanDuel today!

Yankees vs Diamondbacks Betting Trends

• The Yankees have been victorious in 71, or 60.2%, of the 118 contests they have been chosen as favorites in this season.
• New York has a record of 58-36 in contests when sportsbooks favor them by -126 or more on the moneyline.
• The Yankees' games have gone over the total in 67 of their 147 opportunities.
• The Yankees are 76-71-0 against the spread in their 147 games that had a posted line this season.
• The Diamondbacks are 38-43 in games they were listed as the moneyline underdog (winning 46.9% of those games).
• Arizona is 26-32 (winning 44.8% of its games) when it has played as a moneyline underdog of +108 or longer.
• The Diamondbacks have played in 151 games with a set over/under, and have combined with opponents to go over the total 64 times (64-83-4).
• The Diamondbacks have a 78-73-0 record against the spread this season (covering 51.7% of the time).

Yankees Player Leaders

• Ben Rice has an OPS of .884, fueled by an OBP of .360 to go with a slugging percentage of .524. He has a .262 batting average, as well.
• He is 59th in batting average, 30th in on-base percentage, and seventh in slugging among qualified hitters in MLB.
• Rice has recorded a base hit in six straight games. In his last 10 outings he is hitting .333 with two home runs, 10 walks and four RBIs.
• Luis Garcia leads New York in total hits (140) this season while batting .283 with 61 extra-base hits. He's slugging .538 with an on-base percentage of .314.
• Among qualifying batters, he is 19th in batting average, 100th in on-base percentage and third in slugging percentage.
• Cody Bellinger is batting .276 with a .444 slugging percentage and 71 RBI this year.
• Bellinger has logged a hit or more in three games in a row. In his last five games he is hitting .429 with two home runs, two walks and four RBIs.
• Jose Caballero has been key for New York with 92 hits, an OBP of .290 plus a slugging percentage of .372.

Diamondbacks Player Leaders

• Corbin Carroll has 30 doubles, 16 triples, 21 home runs and 70 walks while batting .238. He's slugging .465 with an on-base percentage of .330.
• Including all qualified hitters in the majors, he ranks 102nd in batting average, 69th in on-base percentage and 35th in slugging percentage.
• Ketel Marte is batting .250 with 29 doubles, three triples, 22 home runs and 47 walks. He's slugging .442 with an on-base percentage of .316.
• His batting average is 77th among all qualified players, his on-base percentage ranks 93rd, and he is 54th in slugging.
• Gabriel Moreno has accumulated an on-base percentage of .385, a slugging percentage of .485, and has 136 hits, all club-bests for the Diamondbacks.
• Geraldo Perdomo is batting .252 with 19 doubles, six triples, nine home runs and 89 walks.

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