Twins vs Angels Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 18

Odds updated as of 5:12 a.m.

The Minnesota Twins will face the Los Angeles Angels in MLB action on Friday.

We've got you covered, in terms of the vital info about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Twins vs Angels Game Info

• Minnesota Twins (71-82) vs. Los Angeles Angels (59-94)
• Date: Friday, September 18, 2026
• Time: 9:38 p.m. ET
• Venue: Angel Stadium -- Anaheim, California
• Coverage: ABTV and Twins.TV

Twins vs Angels Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIN: (-126) | LAA: (+108)
• Spread: MIN: -1.5 (+134) | LAA: +1.5 (-162)
• Total: 8.5 -- Over: (-102) | Under: (-120)

Twins vs Angels Probable Starting Pitchers

Probable Pitchers: Connor Prielipp (Twins) - 5-7, 5.24 ERA vs Grayson Rodriguez (Angels) - 4-7, 6.10 ERA

This contest's pitching matchup is set, as the Twins will send Connor Prielipp (5-7) to the mound, while Grayson Rodriguez (4-7) will take the ball for the Angels. Prielipp's team is 11-9-0 against the spread this season in his starts. Prielipp's team has won 75% of his starts when they are favored on the moneyline (3-1). When Rodriguez starts, the Angels are 9-9-0 against the spread. The Angels are 4-13 in Rodriguez's 17 starts this season that they were the moneyline underdog.

Twins vs Angels Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (55%)

Twins vs Angels Moneyline

• Looking at the moneyline for Twins-Angels, Minnesota is the favorite at -126, and Los Angeles is +108 playing at home.

Twins vs Angels Spread

• The Twins are favored by 1.5 runs on the road versus the Angels. The Twins are +134 to cover the spread, while the Angels are -162.

Twins vs Angels Over/Under

• The over/under for the Twins versus Angels contest on Sept. 18 has been set at 8.5, with -102 odds on the over and -120 odds on the under.

Bet on Minnesota Twins vs. Los Angeles Angels on FanDuel today!

Twins vs Angels Betting Trends

• The Twins have come away with 28 wins in the 54 contests they have been listed as the favorites in this season.
• This season Minnesota has been victorious 12 times in 26 chances when named as a favorite of at least -126 on the moneyline.
• The Twins' games have gone over the total in 85 of their 149 opportunities.
• The Twins have an against the spread record of 79-70-0 in 149 games with a line this season.
• The Angels have been the underdog on the moneyline 124 total times this season. They've finished 44-80 in those games.
• Los Angeles is 37-65 (winning just 36.3% of its games) when it has played as a moneyline underdog of +108 or longer.
• The Angels have combined with opponents to hit the over on the total 63 times this season for a 63-86-3 record against the over/under.
• The Angels have an 81-71-0 record against the spread this season.

Twins Player Leaders

• Brooks Lee has 23 doubles, three triples, 23 home runs and 36 walks while batting .248. He has an on-base percentage of .298 and a slugging percentage of .427.
• Among all qualifying hitters in the majors, he ranks 82nd in batting average, 120th in on-base percentage, and 66th in slugging.
• Lee has recorded at least one hit in two games in a row. In his last five games he is hitting .235 with two walks and two RBIs.
• Josh Bell has 28 doubles, a triple, 20 home runs and 48 walks. He's batting .252 and slugging .419 with an on-base percentage of .315.
• He is 72nd in batting average, 97th in on-base percentage and 74th in slugging among qualifying hitters.
• Bell takes a two-game streak with at least one hit into this matchup. In his last five games he is hitting .190 with a home run, a walk and two RBIs.
• Kody Clemens has 120 hits and is batting .240 this season.
• Clemens takes a three-game hitting streak into this game. During his last five outings he is batting .211 with a double, a triple, three walks and an RBI.
• Luke Keaschall has a slash line of .279/.370/.387 this season and a team-best OPS of .757.
• Keaschall brings a three-game hitting streak into this game. During his last five outings he is hitting .450 with three walks and an RBI.

Angels Player Leaders

• Zach Neto has put up a slugging percentage of .440 and has 142 hits, both team-high marks for the Angels. He's batting .241 and with an on-base percentage of .323.
• Including all qualifying hitters, he is 95th in batting average, while his on-base percentage ranks 81st and he is 56th in slugging.
• Mike Trout paces his team with a .379 on-base percentage. He has a batting average of .241 while slugging .423.
• Including all qualifying hitters, he is 95th in batting average, ninth in on-base percentage and 71st in slugging percentage.
• Vaughn Grissom has 22 doubles, 11 home runs and 28 walks while hitting .238.
• Wade Meckler is hitting .294 with 14 doubles, three home runs and 30 walks.

Twins vs Angels Head to Head

• 9/17/2026: 5-4 LAA (Favorite: Angels, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 7/12/2026: 4-2 MIN (Favorite: Twins, Spread: -1.5, Total: 9.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/11/2026: 5-3 MIN (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 7/10/2026: 4-3 LAA (Favorite: Twins, Spread: -1.5, Total: 9.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 9/10/2025: 4-3 LAA (Favorite: Angels, Spread: -1.5, Total: 9.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/9/2025: 12-2 LAA (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/8/2025: 12-3 MIN (Favorite: Angels, Spread: -1.5, Total: 9.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 4/27/2025: 5-0 MIN (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 4/26/2025: 5-1 MIN (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 4/25/2025: 11-4 MIN (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -205, Underdog Moneyline: +172)

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