White Sox vs Royals Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 24

Odds updated as of 2:11 a.m.

In MLB action on Thursday, the Chicago White Sox face the Kansas City Royals.

All the information you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

White Sox vs Royals Game Info

• Chicago White Sox (81-77) vs. Kansas City Royals (68-90)
• Date: Thursday, September 24, 2026
• Time: 2:10 p.m. ET
• Venue: Kauffman Stadium -- Kansas City, Missouri
• Coverage: Royals.TV and CHSN

White Sox vs Royals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHW: (-130) | KC: (+110)
• Spread: CHW: -1.5 (+128) | KC: +1.5 (-154)
• Total: 8.5 -- Over: (-142) | Under: (+116)

White Sox vs Royals Probable Starting Pitchers

Probable Pitchers: David Sandlin (White Sox) - 2-2, 6.29 ERA vs Randy Dobnak (Royals) - 3-4, 3.08 ERA

This contest's pitching matchup is set, as the White Sox will send David Sandlin (2-2) to the mound, while Randy Dobnak (3-4) will get the nod for the Royals. Sandlin's team is 2-3-0 against the spread this season in his starts. When Sandlin starts a game and his team is the favorite on the moneyline, they have a record of 1-2. The Royals have a 7-5-0 ATS record in Dobnak's 12 starts that had a set spread. The Royals have been the underdog on the moneyline in 10 of Dobnak's starts this season, and they went 4-6 in those games.

White Sox vs Royals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Royals win (50.8%)

White Sox vs Royals Moneyline

• Kansas City is a +110 underdog on the moneyline, while Chicago is a -130 favorite on the road.

White Sox vs Royals Spread

• The Royals are hosting the White Sox, and are +1.5 on the runline. The Royals are +128 to cover the spread, and the White Sox are -154.

White Sox vs Royals Over/Under

• The White Sox-Royals contest on Sept. 24 has been given an over/under of 8.5 runs. The over is set at -142 and the under at +116.

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White Sox vs Royals Betting Trends

• The White Sox have been victorious in 23, or 54.8%, of the 42 contests they have been chosen as favorites in this season.
• Chicago has a record of 7-7 when favored by -130 or more this year.
• The White Sox and their opponents have hit the over in 87 of their 155 games with a total set by oddsmakers this season.
• The White Sox have an against the spread record of 87-68-0 in 155 games with a line this season.
• The Royals have won 39% of the games this season they were the moneyline underdog (39-61).
• Kansas City has gone 21-35 when it has played as a moneyline underdog with odds of +110 or longer (37.5%).
• The Royals have had an over/under set by oddsmakers 151 times, and have combined with opponents to go over the total in 69 of those games (69-79-3).
• The Royals have collected a 76-75-0 record ATS this season (covering 50.3% of the time).

White Sox Player Leaders

• Miguel Vargas has 145 hits, which is tops among Chicago hitters this season, while batting .251 with 65 extra-base hits. He has an on-base percentage of .362 and a slugging percentage of .479.
• Among all qualified hitters in the majors, his batting average ranks 78th, his on-base percentage ranks 26th, and he is 26th in slugging.
• Vargas has picked up at least one hit in five games in a row. In his last five games he is batting .353 with a double, two home runs, six walks and six RBIs.
• Chase Meidroth leads Chicago in slugging percentage (.410) thanks to 45 extra-base hits. He's batting .273 with an on-base percentage of .348.
• His batting average ranks 36th among qualified players, his on-base percentage 44th, and his slugging percentage 81st.
• Meidroth enters this game looking to extend his three-game hit streak. During his last five outings he is batting .333 with two home runs, two walks and seven RBIs.
• Sam Antonacci leads Chicago with an OBP of .364 this season while batting .269 with 42 walks and 77 runs scored.
• Antonacci brings a two-game hitting streak into this matchup. In his last five games he is hitting .214 with a double and three RBIs.
• Tristan Peters has been key for Chicago with 114 hits, an OBP of .342 plus a slugging percentage of .447.

Royals Player Leaders

• Bobby Witt Jr. has accumulated a .361 on-base percentage and a .443 slugging percentage, both team-high numbers for the Royals. He's batting .282.
• Including all qualified hitters, he ranks 19th in batting average, while his on-base percentage ranks 28th and he is 52nd in slugging.
• Witt hopes to build on a five-game hitting streak in this matchup. In his last five games he is batting .429 with a double.
• Carter Jensen is batting .237 with 33 doubles, two triples, 25 home runs and 64 walks. He's slugging .454 with an on-base percentage of .323.
• Including all qualifying hitters, he is 102nd in batting average, 83rd in on-base percentage and 40th in slugging percentage.
• Jac Caglianone has 141 hits, a team-high for the Royals.
• Vinnie Pasquantino is hitting .249 with 20 doubles, two triples, 15 home runs and 50 walks.

White Sox vs Royals Head to Head

• 9/23/2026: 5-4 KC (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/22/2026: 14-11 CHW (Favorite: White Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: +100)
• 6/28/2026: 5-4 KC (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 6/27/2026: 2-1 CHW (Favorite: White Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/26/2026: 22-1 CHW (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/14/2026: 6-2 CHW (Favorite: Royals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 5/13/2026: 6-5 CHW (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/12/2026: 6-5 CHW (Favorite: Royals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 4/11/2026: 2-0 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 4/10/2026: 2-0 KC (Favorite: Royals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -180, Underdog Moneyline: +152)

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