White Sox vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 12

Odds updated as of 2:11 a.m.

The MLB slate on Wednesday includes the Chicago White Sox facing the Cincinnati Reds.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

White Sox vs Reds Game Info

• Chicago White Sox (61-57) vs. Cincinnati Reds (57-61)
• Date: Wednesday, August 12, 2026
• Time: 7:40 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and Reds.TV

White Sox vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHW: (-146) | CIN: (+124)
• Spread: CHW: -1.5 (+140) | CIN: +1.5 (-170)
• Total: 8.5 -- Over: (-122) | Under: (+100)

White Sox vs Reds Probable Starting Pitchers

Probable Pitchers: Luis Castillo (White Sox) - 3-9, 5.30 ERA vs Rhett Lowder (Reds) - 4-7, 5.26 ERA

This contest's pitching matchup is set, as the White Sox will send Luis Castillo (3-9) to the mound, while Rhett Lowder (4-7) will get the nod for the Reds. Castillo's team is 6-12-0 against the spread in his starts this season. Castillo's team has been victorious in 30% of the games he's started as the moneyline favorite with a record of 3-7. The Reds have gone 8-9-0 ATS in Lowder's 17 starts that had a set spread. The Reds are 7-7 in Lowder's 14 starts this season that they were the underdog on the moneyline.

White Sox vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: White Sox win (59.6%)

White Sox vs Reds Moneyline

• Cincinnati is the underdog, +124 on the moneyline, while Chicago is a -146 favorite at home.

White Sox vs Reds Spread

• The White Sox are hosting the Reds and are favored by 1.5 runs (+140 to cover) on the runline. Cincinnati is -170 to cover.

White Sox vs Reds Over/Under

• A total of 8.5 runs has been set for the White Sox-Reds game on Aug. 12, with the over available at -122 and the under at +100.

Bet on Chicago White Sox vs. Cincinnati Reds on FanDuel today!

White Sox vs Reds Betting Trends

• The White Sox have come away with 13 wins in the 22 contests they have been listed as the favorites in this season.
• Chicago has a record of 3-1 when favored by -146 or more this year.
• Contests with the White Sox have gone over the total set by bookmakers in 64 of 115 chances this season.
• The White Sox are 67-48-0 against the spread in their 115 games that had a posted line this season.
• The Reds have compiled a 37-39 record in games they were the underdog on the moneyline (winning 48.7% of those games).
• Cincinnati has a record of 9-15 in games it has played as a moneyline underdog with odds of +124 or longer (37.5%).
• In the 115 games oddsmakers have set an over/under for the Reds, they have combined with opponents to go over the total 61 times (61-52-2).
• The Reds have collected a 61-54-0 record against the spread this season (covering 53% of the time).

White Sox Player Leaders

• Miguel Vargas leads Chicago with 102 hits, batting .235 this season with 52 extra-base hits. He has an on-base percentage of .342 and a slugging percentage of .472.
• Among all qualified hitters in baseball, he ranks 108th in batting average, 55th in on-base percentage, and 31st in slugging.
• Vargas hopes to build on a three-game hitting streak in this matchup. During his last five outings he is hitting .150 with a double, a home run, four walks and an RBI.
• Chase Meidroth leads Chicago in slugging percentage (.404) thanks to 32 extra-base hits. He's batting .274 with an on-base percentage of .350.
• Among qualifiers, he ranks 34th in batting average, 42nd in on-base percentage and 93rd in slugging percentage.
• Meidroth has picked up a hit in three games in a row. During his last five outings he is hitting .300 with a double, two home runs, three walks and six RBIs.
• Munetaka Murakami has 71 hits this season and has a slash line of .237/.369/.538.
• Murakami enters this game with four games in a row with at least one hit. During his last five outings he is batting .190 with two doubles, two home runs, three walks and three RBIs.
• Sam Antonacci has 92 hits this season and a team-best OBP of .364.

Reds Player Leaders

• Sal Stewart has a .472 slugging percentage, which leads the Reds. He's batting .254 with an on-base percentage of .331.
• Including all qualified hitters in the big leagues, he is 74th in batting average, 76th in on-base percentage and 31st in slugging percentage.
• Stewart hopes to build on a three-game hitting streak in this matchup. In his last five games he is hitting .238 with a home run and an RBI.
• Elly De La Cruz has 106 hits with a .351 on-base percentage to pace his team in both. He has a batting average of .271 while slugging .496.
• His batting average ranks 41st among all qualified players, his on-base percentage is 40th, and he is 17th in slugging.
• JJ Bleday has 12 doubles, a triple, 20 home runs and 54 walks while batting .223.
• Tyler Stephenson is hitting .248 with 16 doubles, 10 home runs and 35 walks.

White Sox vs Reds Head to Head

• 8/11/2026: 5-4 CIN (Favorite: White Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +142)
• 5/15/2025: 7-1 CIN (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 5/14/2025: 4-2 CHW (Favorite: Reds, Spread: -1.5, Total: 8.5, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 4/14/2024: 11-4 CIN (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 4/13/2024: 5-0 CIN (Favorite: Reds, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 4/12/2024: 11-1 CIN (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -176, Underdog Moneyline: +148)
• 5/7/2023: 17-4 CHW (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/6/2023: 5-3 CIN (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 5/5/2023: 5-4 CHW (Favorite: Reds, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)

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