Twins vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 3

Odds updated as of 10:12 a.m.

The MLB's Wednesday slate includes the Minnesota Twins facing the Chicago White Sox.

We've got you covered, in terms of the most important info regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Twins vs White Sox Game Info

• Minnesota Twins (62-76) vs. Chicago White Sox (51-88)
• Date: Wednesday, September 3, 2025
• Time: 7:40 p.m. ET
• Venue: Target Field -- Minneapolis, Minnesota
• Coverage: MNNT and CHSN

Twins vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIN: (-184) | CHW: (+154)
• Spread: MIN: -1.5 (+112) | CHW: +1.5 (-134)
• Total: 8.5 -- Over: (-115) | Under: (-105)

Twins vs White Sox Probable Starting Pitchers

Probable Pitchers: Zebby Matthews (Twins) - 4-4, 5.06 ERA vs Yoendrys Gomez (White Sox) - 3-2, 5.20 ERA

The probable pitchers are Zebby Matthews (4-4) for the Twins and Yoendrys Gomez (3-2) for the White Sox. When Matthews starts, his team is 5-7-0 against the spread this season. Matthews' team has a record of 4-3 this season when he starts and they are the favorite on the moneyline. The White Sox have a 3-1-0 record against the spread in Gomez's starts. The White Sox have a 3-1 record in Gomez's four starts this season when they were the moneyline underdog.

Twins vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (68.4%)

Twins vs White Sox Moneyline

• Chicago is the underdog, +154 on the moneyline, while Minnesota is a -184 favorite at home.

Twins vs White Sox Spread

• The White Sox are +1.5 on the run line against the Twins. The White Sox are -134 to cover, and the Twins are +112.

Twins vs White Sox Over/Under

• An over/under of 8.5 has been set for Twins-White Sox on Sept. 3, with the over being -115 and the under -105.

Bet on Minnesota Twins vs. Chicago White Sox on FanDuel today!

Twins vs White Sox Betting Trends

• The Twins have been victorious in 39, or 49.4%, of the 79 contests they have been chosen as favorites in this season.
• This season Minnesota has come away with a win eight times in 14 chances when named as a favorite of at least -184 on the moneyline.
• Contests with the Twins have gone over the total set by bookmakers in 63 of 133 chances this season.
• The Twins are 65-68-0 against the spread in their 133 games with a line set by sportsbooks this season.
• The White Sox have won 47 of the 131 games they were listed as the moneyline underdog this season (35.9%).
• In games it has played as a moneyline underdog with odds of +154 or longer, Chicago has a 16-42 record (winning just 27.6% of its games).
• The White Sox have played in 134 games with an over/under set, and have combined with opponents to go over the total 62 times (62-64-8).
• The White Sox have put together a 75-59-0 record against the spread this season (covering 56% of the time).

Twins Player Leaders

• Byron Buxton leads Minnesota in total hits (110) this season while batting .272 with 51 extra-base hits. He has an on-base percentage of .333 and a slugging percentage of .553.
• Among all qualifying hitters in baseball, his batting average ranks 39th, his on-base percentage ranks 70th, and he is fifth in slugging.
• Buxton has picked up at least one hit in six games in a row. During his last 10 games he is batting .282 with two doubles, a triple, four home runs, four walks and 11 RBIs.
• Trevor Larnach has hit 16 homers this season while driving in 55 runs. He's batting .254 this season and slugging .414 with an on-base percentage of .327.
• He is 88th in batting average, 84th in on-base percentage and 90th in slugging among qualifying hitters.
• Larnach has picked up at least one hit in four straight games. In his last five games he is hitting .529 with a double, a walk and four RBIs.
• Brooks Lee has collected 101 base hits, an OBP of .293 and a slugging percentage of .383 this season.
• Lee heads into this matchup with three games in a row with at least one hit. During his last five outings he is hitting .158 with a walk and an RBI.
• Ryan Jeffers has 98 hits this season and a team-best OBP of .349.

White Sox Player Leaders

• Andrew Benintendi is batting .245 with 15 doubles, two triples, 17 home runs and 34 walks. He's slugging .428 with an on-base percentage of .307.
• Lenyn Sosa has collected 118 hits while slugging .436. Both are team-highs. He has a batting average of .265 with an on-base percentage of .296.
• He ranks 57th in batting average, 136th in on-base percentage and 76th in slugging percentage in the majors.
• Chase Meidroth is batting .253 with 14 doubles, four home runs and 38 walks.
• Mike Tauchman is batting .271 with 15 doubles, a triple, eight home runs and 40 walks.

Twins vs White Sox Head to Head

• 9/2/2025: 12-3 CHW (Favorite: Twins, Spread: -1.5, Total: 9.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 9/1/2025: 6-5 CHW (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 8/24/2025: 8-0 CHW (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/23/2025: 7-3 CHW (Favorite: Twins, Spread: -1.5, Total: 9.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 8/22/2025: 9-7 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 4/24/2025: 3-0 CHW (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 4/23/2025: 6-3 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 4/22/2025: 4-2 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -250, Underdog Moneyline: +205)
• 4/2/2025: 6-1 MIN (Favorite: Twins, Spread: -1.5, Total: 7, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 4/1/2025: 8-3 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -164, Underdog Moneyline: +138)

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