Royals vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for May 7

Odds updated as of 9:11 p.m.

The Kansas City Royals will face the Cleveland Guardians in MLB action on Thursday.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Royals vs Guardians Game Info

• Kansas City Royals (17-19) vs. Cleveland Guardians (18-19)
• Date: Thursday, May 7, 2026
• Time: 2:10 p.m. ET
• Venue: Kauffman Stadium -- Kansas City, Missouri
• Coverage: Royals.TV and CleGuardians.TV

Royals vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: KC: (-146) | CLE: (+124)
• Spread: KC: -1.5 (+134) | CLE: +1.5 (-162)
• Total: 9 -- Over: (-115) | Under: (-105)

Royals vs Guardians Probable Starting Pitchers

Probable Pitchers: Seth Lugo (Royals) - 1-1, 2.68 ERA vs Slade Cecconi (Guardians) - 1-4, 6.56 ERA

The Royals will look to Seth Lugo (1-1) against the Guardians and Slade Cecconi (1-4). Lugo and his team have a record of 5-2-0 against the spread when he starts. Lugo's team is 2-1 this season when he starts and they are the moneyline favorite. The Guardians have a 2-5-0 ATS record in Cecconi's seven starts that had a set spread. The Guardians have been the moneyline underdog in six of Cecconi's starts this season, and they went 1-5 in those games.

Royals vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Royals win (60.9%)

Royals vs Guardians Moneyline

• Cleveland is the underdog, +124 on the moneyline, while Kansas City is a -146 favorite at home.

Royals vs Guardians Spread

• The Royals are favored by 1.5 runs at home versus the Guardians. The Royals are +134 to cover the spread, while the Guardians are -162.

Royals vs Guardians Over/Under

• A total of 9 runs has been set for the Royals-Guardians contest on May 7, with the over available at -115 and the under at -105.

Bet on Kansas City Royals vs. Cleveland Guardians on FanDuel today!

Royals vs Guardians Betting Trends

• The Royals have won in nine, or 60%, of the 15 contests they have been named as odds-on favorites in this year.
• Kansas City has a record of 3-2 when favored by -146 or more this year.
• The Royals and their opponents have gone over the total this season in 14 of their 34 opportunities.
• In 34 games with a line this season, the Royals have a mark of 17-17-0 against the spread.
• The Guardians have won nine of the 19 games they were listed as the moneyline underdog this season (47.4%).
• Cleveland has a record of 4-4 in games it has played as a moneyline underdog with odds of +124 or longer (50%).
• The Guardians have had an over/under set by oddsmakers 36 times, and have combined with opponents to go over the total in 18 of those games (18-18-0).
• The Guardians have covered 50% of their games this season, going 18-18-0 against the spread.

Royals Player Leaders

• Bobby Witt Jr. has 41 hits to go with a slugging percentage of .434, both of which lead Kansas City hitters this season. He has a .287 batting average and an on-base percentage of .358.
• Among qualified batters, he is 35th in batting average, his on-base percentage ranks 53rd, and he is 63rd in slugging.
• Witt will look for his sixth straight game with a hit in this contest. During his last five outings he is hitting .273 with a double, a home run, a walk and an RBI.
• Maikel Garcia is batting .256 with nine doubles, a triple, three home runs and 14 walks, while slugging .406 with an on-base percentage of .322.
• His batting average ranks 76th among qualified players, his on-base percentage 104th, and his slugging percentage 85th.
• Vinnie Pasquantino is batting .192 with a .352 slugging percentage and 18 RBI this year.
• Salvador Perez has been key for Kansas City with 29 hits, an OBP of .245 plus a slugging percentage of .353.
• Perez takes a two-game hitting streak into this matchup. During his last five outings he is hitting .263 with two doubles and five RBIs.

Guardians Player Leaders

• Jose Ramirez is batting .212 with eight doubles, six home runs and 24 walks. He's slugging .401 with an on-base percentage of .329.
• He is 144th in batting average, 93rd in on-base percentage and 89th in slugging percentage among all qualifying batters in the majors.
• Chase DeLauter paces his team with 35 hits and a .388 OBP, with a team-best .543 slugging percentage. He has a batting average of .302.
• Including all qualified hitters, he is 25th in batting average, 22nd in on-base percentage and 15th in slugging percentage.
• Brayan Rocchio has four doubles, three home runs and 11 walks while batting .261.
• Angel Martinez is hitting .271 with seven doubles, five home runs and four walks.

Royals vs Guardians Head to Head

• 5/5/2026: 5-3 KC (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/4/2026: 6-2 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 4/8/2026: 10-2 CLE (Favorite: Royals, Spread: -1.5, Total: 7, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/7/2026: 2-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 6.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 4/6/2026: 4-2 KC (Favorite: Guardians, Spread: -1.5, Total: 7, Favorite Moneyline: -118, Underdog Moneyline: +100)
• 9/11/2025: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/10/2025: 4-3 KC (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/9/2025: 2-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/8/2025: 10-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/27/2025: 4-1 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)

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