Reds vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for May 14

Odds updated as of 5:14 a.m.

The Wednesday slate in MLB includes a matchup between the Cincinnati Reds and the Chicago White Sox.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Reds vs White Sox Game Info

• Cincinnati Reds (20-23) vs. Chicago White Sox (13-29)
• Date: Wednesday, May 14, 2025
• Time: 7:14 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: FDSOH and CHSN

Reds vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CIN: (-225) | CHW: (+188)
• Spread: CIN: -1.5 (-110) | CHW: +1.5 (-110)
• Total: 9 -- Over: (-105) | Under: (-115)

Reds vs White Sox Probable Starting Pitchers

Probable Pitchers: Nick Lodolo (Reds) - 3-3, 3.23 ERA vs Davis Martin (White Sox) - 1-4, 4.01 ERA

The Reds will give the ball to Nick Lodolo (3-3, 3.23 ERA), who is eyeing win No. 4 on the season, and the White Sox will counter with Davis Martin (1-4, 4.01 ERA). Lodolo and his team are 5-3-0 ATS this season when he starts. Lodolo's team has won 50% of his starts when they are favored on the moneyline (2-2). The White Sox are 2-5-0 ATS in Martin's seven starts that had a set spread. The White Sox have been the underdog on the moneyline in seven of Martin's starts this season, and they went 1-6 in those matchups.

Reds vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (68.7%)

Reds vs White Sox Moneyline

• Looking at the moneyline for White Sox-Reds, Chicago is the underdog at +188, and Cincinnati is -225 playing at home.

Reds vs White Sox Spread

• The Reds are hosting the White Sox and are favored by 1.5 runs (-110 to cover) on the runline. Chicago is -110 to cover.

Reds vs White Sox Over/Under

• Reds versus White Sox, on May 14, has an over/under of 9, with the over being -105 and the under -115.

Bet on Cincinnati Reds vs. Chicago White Sox on FanDuel today!

Reds vs White Sox Betting Trends

• The Reds have won in nine, or 56.2%, of the 16 contests they have been named as odds-on favorites in this year.
• Oddsmakers have given Cincinnati the best odds of winning it has seen this season, with a -225 moneyline listed for this contest.
• The Reds and their opponents have gone over in 18 of their 41 games with a total set by sportsbooks this season.
• The Reds have an against the spread mark of 21-20-0 in 41 games with a line this season.
• The White Sox have been the moneyline underdog 40 total times this season. They've finished 12-28 in those games.
• Chicago is 2-13 (winning only 13.3% of its games) when playing as a moneyline underdog of +188 or longer.
• The White Sox have played in 41 games with an over/under set, and have combined with opponents to go over the total 19 times (19-20-2).
• The White Sox have gone 22-19-0 against the spread this season.

Reds Player Leaders

• Elly De La Cruz has 42 hits, which is tops among Cincinnati hitters this season, while batting .250 with 12 extra-base hits. He has an on-base percentage of .324 and a slugging percentage of .405.
• He ranks 89th in batting average, 91st in on-base percentage, and 88th in slugging among all qualifying hitters in the majors.
• TJ Friedl leads Cincinnati in slugging percentage (.382) thanks to 10 extra-base hits. He's batting .274 with an on-base percentage of .359.
• Among qualifying hitters, his batting average ranks him 48th, his on-base percentage 44th, and his slugging percentage 107th.
• Gavin Lux leads Cincinnati in OBP (.370) this season, fueled by 37 hits.
• Jose Trevino has three home runs, 10 RBI and a batting average of .307 this season.

White Sox Player Leaders

• Miguel Vargas has accumulated a team-best OBP (.314), while pacing the White Sox in hits (31). He's batting .221 and slugging.
• Including all qualified hitters, he is 128th in batting average, while his on-base percentage is 102nd and he is 128th in slugging.
• Luis Robert is batting .179 with three doubles, five home runs and 20 walks. He's slugging .313 with an on-base percentage of .284.
• He is currently 156th in batting average, 130th in on-base percentage and 147th in slugging percentage among all qualifying hitters.
• Andrew Vaughn is hitting .192 with seven doubles, five home runs and seven walks.
• Matthew Thaiss is hitting .224 with four doubles, a home run and 19 walks.

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