Padres vs Angels Prediction, Odds, Moneyline, Spread & Over/Under for May 14

Odds updated as of 7:11 a.m.

The San Diego Padres are among the MLB teams busy on Wednesday, up against the Los Angeles Angels.

All the info you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Padres vs Angels Game Info

• San Diego Padres (26-15) vs. Los Angeles Angels (17-24)
• Date: Wednesday, May 14, 2025
• Time: 9:40 p.m. ET
• Venue: PETCO Park -- San Diego, California
• Coverage: SDPA and FDSW

Padres vs Angels Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-184) | LAA: (+154)
• Spread: SD: -1.5 (+106) | LAA: +1.5 (-128)
• Total: 8.5 -- Over: (-124) | Under: (+102)

Padres vs Angels Probable Starting Pitchers

Probable Pitchers: Randy Vasquez (Padres) - 2-3, 3.76 ERA vs Kyle Hendricks (Angels) - 1-4, 5.30 ERA

This contest's pitching matchup is set, as the Padres will send Randy Vasquez (2-3) to the mound, while Kyle Hendricks (1-4) will get the nod for the Angels. Vasquez's team is 4-3-0 against the spread in his starts this season. Vasquez's team won his only start as a favorite this season. When Hendricks starts, the Angels are 4-3-0 against the spread. The Angels have a 3-4 record in Hendricks' seven starts this season when they were the moneyline underdog.

Padres vs Angels Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (65.7%)

Padres vs Angels Moneyline

• San Diego is the favorite, -184 on the moneyline, while Los Angeles is a +154 underdog on the road.

Padres vs Angels Spread

• The Padres are 1.5-run home favorites on the runline against the Angels. The Padres are +106 to cover, and the Angels are -128.

Padres vs Angels Over/Under

• A combined run total of 8.5 has been set for Padres-Angels on May 14, with the over at -124 and the under at +102.

Bet on San Diego Padres vs. Los Angeles Angels on FanDuel today!

Padres vs Angels Betting Trends

• The Padres have been victorious in 15, or 71.4%, of the 21 contests they have been chosen as favorites in this season.
• This year San Diego has won five of seven games when listed as at least -184 on the moneyline.
• The Padres and their opponents have gone over the total this season in 19 of their 40 opportunities.
• In 40 games with a line this season, the Padres have a mark of 24-16-0 against the spread.
• The Angels have won 13 of the 33 games they were the underdog on the moneyline this season (39.4%).
• Los Angeles has a record of 2-4 when it has played as a moneyline underdog with odds of +154 or longer (33.3%).
• The Angels have combined with opponents to go over the total 23 times this season for a 23-17-1 record against the over/under.
• The Angels have gone 16-25-0 ATS this season.

Padres Player Leaders

• Fernando Tatis Jr. leads San Diego in total hits (49) this season while batting .316 with 17 extra-base hits. He has an on-base percentage of .389 and a slugging percentage of .574.
• Among all qualifying hitters, he ranks ninth in batting average, his on-base percentage ranks 16th, and he is eighth in slugging.
• Tatis has picked up at least one hit in seven straight games. In his last 10 outings he is batting .238 with two doubles, three home runs, four walks and eight RBIs.
• Manny Machado has a slash line of .331/.396/.483 this season and a team-best OPS of .880.
• He is seventh in batting average, 11th in on-base percentage and 35th in slugging in the majors.
• Machado has picked up a hit in 13 games in a row. In his last 10 games he is batting .500 with four doubles, a home run, six walks and seven RBIs.
• Luis Arraez has 41 hits this season and has a slash line of .287/.325/.406.
• Arraez brings a two-game hitting streak into this matchup. During his last five outings he is batting .320 with a triple and three RBIs.
• Xander Bogaerts has two home runs, 17 RBI and a batting average of .243 this season.

Angels Player Leaders

• Nolan Schanuel has put up a team-best OBP (.348) and slugging percentage (.368). He's batting .265.
• Including all qualifying players, he is 62nd in batting average, while his on-base percentage is 57th and he is 119th in slugging.
• Joseph Ward has six doubles, nine home runs and nine walks while hitting .185. He's slugging .395 with an on-base percentage of .226.
• Including all qualifying hitters, he is 153rd in batting average, 160th in on-base percentage and 97th in slugging percentage.
• Zach Neto is hitting .278 with five doubles, six home runs and five walks.
• Jorge Soler has eight doubles, six home runs and 13 walks while batting .221.

Padres vs Angels Head to Head

• 5/13/2025: 6-4 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 5/12/2025: 9-5 LAA (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 6/5/2024: 3-2 LAA (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 6/4/2024: 4-2 LAA (Favorite: Angels, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 6/3/2024: 2-1 LAA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 7/5/2023: 5-3 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 7/4/2023: 8-5 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 7/3/2023: 10-3 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -200, Underdog Moneyline: +168)

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