Reds vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for April 28

Odds updated as of 6:12 p.m.

Tuesday's slate in the MLB includes a matchup between the Cincinnati Reds and the Colorado Rockies.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info regarding this matchup.

Reds vs Rockies Game Info

• Cincinnati Reds (18-10) vs. Colorado Rockies (13-16)
• Date: Tuesday, April 28, 2026
• Time: 6:40 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: Reds.TV and Rockies.TV

Reds vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CIN: (-198) | COL: (+166)
• Spread: CIN: -1.5 (+108) | COL: +1.5 (-130)
• Total: 8.5 -- Over: (-112) | Under: (-108)

Reds vs Rockies Probable Starting Pitchers

Probable Pitchers: Chase Burns (Reds) - 2-1, 2.57 ERA vs Kyle Freeland (Rockies) - 1-1, 2.30 ERA

The Reds will look to Chase Burns (2-1) against the Rockies and Kyle Freeland (1-1). Burns and his team have a record of 2-3-0 against the spread when he starts. Burns' team is 2-2 this season when he starts and they are the moneyline favorite. The Rockies are 3-1-0 against the spread when Freeland starts. The Rockies have been the underdog on the moneyline in four of Freeland's starts this season, and they went 2-2 in those matchups.

Reds vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (66.8%)

Reds vs Rockies Moneyline

• Looking at the moneyline for Rockies-Reds, Colorado is the underdog at +166, and Cincinnati is -198 playing at home.

Reds vs Rockies Spread

• The Reds are hosting the Rockies and are favored by 1.5 runs (+108 to cover) on the runline. Colorado is -130 to cover.

Reds vs Rockies Over/Under

• A combined run total of 8.5 has been set for Reds-Rockies on April 28, with the over at -112 and the under at -108.

Bet on Cincinnati Reds vs. Colorado Rockies on FanDuel today!

Reds vs Rockies Betting Trends

• The Reds have won in four of the seven contests they have been named as odds-on favorites in this year.
• Oddsmakers have given Cincinnati the best odds of winning it has seen this season, with a -198 moneyline listed for this contest.
• Contests with the Reds have gone over the total set by oddsmakers in 16 of 28 chances this season.
• The Reds are 17-11-0 against the spread in their 28 games with a line set by sportsbooks this season.
• The Rockies have put together a 13-16 record in games they were the underdog on the moneyline (winning 44.8% of those games).
• Colorado is 6-5 (winning 54.5% of its games) when playing as a moneyline underdog of +166 or longer.
• In the 29 games bookmakers have set an over/under for the Rockies, they have combined with opponents to go over the total 10 times (10-19-0).
• The Rockies have a 19-10-0 record against the spread this season (covering 65.5% of the time).

Reds Player Leaders

• Sal Stewart has 30 hits and an OBP of .385, both of which rank first among Cincinnati hitters this season. He has a .291 batting average and a slugging percentage of .602.
• Among qualified hitters in baseball, he is 31st in batting average, 21st in on-base percentage, and sixth in slugging.
• Elly De La Cruz has hit nine homers this season while driving in 20 runs. He's batting .274 this season and slugging .558 with an on-base percentage of .349.
• Among all qualified hitters, he ranks 49th in batting average, 61st in on-base percentage and 13th in slugging percentage.
• De La Cruz takes a three-game streak with at least one hit into this matchup. In his last five games he is batting .333 with three home runs, three walks and seven RBIs.
• Matt McLain has collected 21 base hits, an OBP of .339 and a slugging percentage of .327 this season.
• Nathaniel Lowe has four home runs, 10 RBI and a batting average of .256 this season.
• Lowe has hit safely in five straight games. During his last five outings he is hitting .333 with a double, four home runs, a walk and five RBIs.

Rockies Player Leaders

• Mickey Moniak is batting .316 with five doubles, eight home runs and five walks. He's slugging .684 with an on-base percentage of .353.
• Moniak hopes to build on an 11-game hitting streak in this matchup. In his last 10 outings he is batting .385 with four doubles, three home runs, four walks and six RBIs.
• T.J. Rumfield is hitting .250 with four doubles, a triple, three home runs and 11 walks. He's slugging .400 with an on-base percentage of .327.
• He is currently 80th in batting average, 95th in on-base percentage and 92nd in slugging percentage among all qualified hitters.
• Troy Johnston has accumulated a team-high OBP (.371) and slugging percentage (.449).
• Hunter Goodman's 25 hits pace his team.

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