Pirates vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for April 30

Odds updated as of 12:13 p.m.

The Pittsburgh Pirates versus the St. Louis Cardinals is on the MLB schedule for Thursday.

We've got you covered, in terms of the most important information regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Pirates vs Cardinals Game Info

• Pittsburgh Pirates (16-15) vs. St. Louis Cardinals (17-13)
• Date: Thursday, April 30, 2026
• Time: 12:35 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: SportsNet PT and Cardinals.TV

Pirates vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PIT: (-245) | STL: (+200)
• Spread: PIT: -1.5 (-110) | STL: +1.5 (-110)
• Total: 7 -- Over: (-112) | Under: (-108)

Pirates vs Cardinals Probable Starting Pitchers

Probable Pitchers: Paul Skenes (Pirates) - 4-1, 2.48 ERA vs Hunter Dobbins (Cardinals) - 0-0, 0.00 ERA

The Pirates will look to Paul Skenes (4-1) versus the Cardinals and Hunter Dobbins. Skenes and his team have a record of 4-2-0 against the spread when he starts. Skenes' team has won 80% of his starts when they are favored on the moneyline (4-1). Last season Dobbins and his team finished 10-1-0 against the spread when he pitched. Dobbins and his team went 5-1 in games he pitched when they were moneyline underdogs a season ago.

Pirates vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Pirates win (67.5%)

Pirates vs Cardinals Moneyline

• Pittsburgh is the favorite, -245 on the moneyline, while St. Louis is a +200 underdog on the road.

Pirates vs Cardinals Spread

• The Pirates are hosting the Cardinals and are favored by 1.5 runs (-110 to cover) on the runline. St. Louis is -110 to cover.

Pirates vs Cardinals Over/Under

• Pirates versus Cardinals on April 30 has an over/under of 7 runs, with the odds on the over -112 and the under set at -108.

Bet on Pittsburgh Pirates vs. St. Louis Cardinals on FanDuel today!

Pirates vs Cardinals Betting Trends

• The Pirates have won in 11, or 61.1%, of the 18 contests they have been named as odds-on favorites in this year.
• Pittsburgh has not played a game this season with better moneyline odds than -245.
• The Pirates' games have gone over the total in 17 of their 31 opportunities.
• The Pirates have posted a record of 17-14-0 against the spread this season.
• The Cardinals have won 55.6% of the games this season they were the moneyline underdog (15-12).
• St. Louis has yet to play a game with moneyline odds of +200 or longer.
• In the 30 games oddsmakers have set an over/under for the Cardinals, they have combined with opponents to go over the total 16 times (16-13-1).
• The Cardinals have gone 18-12-0 ATS this season.

Pirates Player Leaders

• Oneil Cruz leads Pittsburgh in total hits (31) this season while batting .256 with 14 extra-base hits. He has an on-base percentage of .318 and a slugging percentage of .521.
• Among all qualified batters in the majors, his batting average ranks 74th, his on-base percentage ranks 108th, and he is 23rd in slugging.
• Ryan O'Hearn leads the Pirates with an OPS of .902. He has a slash line of .317/.402/.500 this season.
• He is 12th in batting average, 14th in on-base percentage and 30th in slugging in the majors.
• O'Hearn takes a three-game streak with at least one hit into this matchup. During his last five outings he is hitting .250 with a home run, a walk and four RBIs.
• Brandon Lowe has 25 hits this season and has a slash line of .245/.336/.520.
• Lowe has logged a hit or more in two games in a row. In his last five games he is batting .222 with three doubles and a walk.
• Bryan Reynolds is batting .236 with a .380 OBP and 17 RBI for Pittsburgh this season.

Cardinals Player Leaders

• JJ Wetherholt has five doubles, six home runs and 16 walks while batting .248. He's slugging .451 with an on-base percentage of .370.
• Including all the qualifying hitters in the big leagues, he ranks 85th in batting average, 35th in on-base percentage and 57th in slugging percentage.
• Wetherholt enters this matchup on a six-game hitting streak. During his last 10 games he is batting .268 with four doubles, three home runs, two walks and six RBIs.
• Alec Burleson is hitting .263 with eight doubles, four home runs and 15 walks. He's slugging .439 with an on-base percentage of .346.
• Including all qualified hitters, he is 62nd in batting average, 63rd in on-base percentage and 64th in slugging percentage.
• Ivan Herrera has accumulated a team-high .420 on-base percentage.
• Jordan Walker has racked up 31 hits while slugging .532. Both lead his team.

Pirates vs Cardinals Head to Head

• 4/29/2026: 5-4 STL (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 4/28/2026: 11-7 STL (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 4/27/2026: 4-2 STL (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 8/28/2025: 4-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/27/2025: 2-1 PIT (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 8/26/2025: 8-3 PIT (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/25/2025: 7-6 STL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/2/2025: 5-0 PIT (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/1/2025: 1-0 PIT (Favorite: Pirates, Spread: -1.5, Total: 7, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 5/7/2025: 5-0 STL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -188, Underdog Moneyline: +158)

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